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2550 related items for PubMed ID: 25733818

  • 1. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Zhou ZW, Pan ST, He ZX, Zhang X, Yang T, Pan SY, Duan W, He SM, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1027-62. PubMed ID: 25733818
    [Abstract] [Full Text] [Related]

  • 2. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [Abstract] [Full Text] [Related]

  • 3. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 4. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [Abstract] [Full Text] [Related]

  • 5. Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.
    Zi D, Zhou ZW, Yang YJ, Huang L, Zhou ZL, He SM, He ZX, Zhou SF.
    Int J Mol Sci; 2015 Nov 13; 16(11):27228-51. PubMed ID: 26580601
    [Abstract] [Full Text] [Related]

  • 6. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 13; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 7. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F, Wang Q, Zhou ZW, Yu SN, Pan ST, He ZX, Zhang X, Wang D, Yang YX, Yang T, Sun T, Li M, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 13; 9():537-60. PubMed ID: 25632222
    [Abstract] [Full Text] [Related]

  • 8. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 13; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 9. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang YX, Zhang X, Duan W, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 13; 9():425-64. PubMed ID: 25624750
    [Abstract] [Full Text] [Related]

  • 10. [Effect of danusertib on cell cycle, apoptosis and autophagy of hepatocellular carcinoma HepG2 cells in vitro].
    Zhu Q, Luo M, Zhou C, Chen Z, Huang W, Huang J, Zhao S, Yu X.
    Nan Fang Yi Ke Da Xue Xue Bao; 2018 Dec 30; 38(12):1476-1484. PubMed ID: 30613017
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells.
    He SJ, Shu LP, Zhou ZW, Yang T, Duan W, Zhang X, He ZX, Zhou SF.
    Cancer Lett; 2016 Nov 28; 382(2):215-230. PubMed ID: 27612557
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 28; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 13. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
    Wang YY, Yang YX, Zhao R, Pan ST, Zhe H, He ZX, Duan W, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 28; 9():993-1026. PubMed ID: 25733817
    [Abstract] [Full Text] [Related]

  • 14. Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
    Ren BJ, Zhou ZW, Zhu DJ, Ju YL, Wu JH, Ouyang MZ, Chen XW, Zhou SF.
    Int J Mol Sci; 2015 Dec 29; 17(1):. PubMed ID: 26729093
    [Abstract] [Full Text] [Related]

  • 15. Epithelial to mesenchymal transition is associated with rapamycin resistance.
    Holder AM, Akcakanat A, Adkins F, Evans K, Chen H, Wei C, Milton DR, Li Y, Do KA, Janku F, Meric-Bernstam F.
    Oncotarget; 2015 Aug 14; 6(23):19500-13. PubMed ID: 25944619
    [Abstract] [Full Text] [Related]

  • 16. Alisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cells.
    Liu Z, Wang F, Zhou ZW, Xia HC, Wang XY, Yang YX, He ZX, Sun T, Zhou SF.
    Am J Transl Res; 2017 Aug 14; 9(3):845-873. PubMed ID: 28386317
    [Abstract] [Full Text] [Related]

  • 17. Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
    Nagappan A, Lee WS, Yun JW, Lu JN, Chang SH, Jeong JH, Kim GS, Jung JM, Hong SC.
    PLoS One; 2017 Aug 14; 12(3):e0174591. PubMed ID: 28355296
    [Abstract] [Full Text] [Related]

  • 18. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 14; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 19. Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis.
    Choi CH, Jung YK, Oh SH.
    Mol Pharmacol; 2010 Jul 14; 78(1):114-25. PubMed ID: 20371669
    [Abstract] [Full Text] [Related]

  • 20. Resveratrol induces apoptosis and autophagy in T-cell acute lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating p38-MAPK.
    Ge J, Liu Y, Li Q, Guo X, Gu L, Ma ZG, Zhu YP.
    Biomed Environ Sci; 2013 Nov 14; 26(11):902-11. PubMed ID: 24331535
    [Abstract] [Full Text] [Related]

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