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Journal Abstract Search


123 related items for PubMed ID: 25742030

  • 1. Functional evaluation of biological neurotoxins in networked cultures of stem cell-derived central nervous system neurons.
    Hubbard K, Beske P, Lyman M, McNutt P.
    J Vis Exp; 2015 Feb 05; (96):. PubMed ID: 25742030
    [Abstract] [Full Text] [Related]

  • 2. Botulinum and Tetanus Neurotoxin-Induced Blockade of Synaptic Transmission in Networked Cultures of Human and Rodent Neurons.
    Beske PH, Bradford AB, Grynovicki JO, Glotfelty EJ, Hoffman KM, Hubbard KS, Tuznik KM, McNutt PM.
    Toxicol Sci; 2016 Feb 05; 149(2):503-15. PubMed ID: 26615023
    [Abstract] [Full Text] [Related]

  • 3. Accelerated intoxication of GABAergic synapses by botulinum neurotoxin A disinhibits stem cell-derived neuron networks prior to network silencing.
    Beske PH, Scheeler SM, Adler M, McNutt PM.
    Front Cell Neurosci; 2015 Feb 05; 9():159. PubMed ID: 25954159
    [Abstract] [Full Text] [Related]

  • 4. Embryonic stem cell-derived neurons are a novel, highly sensitive tissue culture platform for botulinum research.
    McNutt P, Celver J, Hamilton T, Mesngon M.
    Biochem Biophys Res Commun; 2011 Feb 04; 405(1):85-90. PubMed ID: 21215258
    [Abstract] [Full Text] [Related]

  • 5. High yield derivation of enriched glutamatergic neurons from suspension-cultured mouse ESCs for neurotoxicology research.
    Hubbard KS, Gut IM, Lyman ME, Tuznik KM, Mesngon MT, McNutt PM.
    BMC Neurosci; 2012 Oct 24; 13():127. PubMed ID: 23095170
    [Abstract] [Full Text] [Related]

  • 6. Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinum toxin A and C, but not tetanus toxin.
    Capogna M, McKinney RA, O'Connor V, Gähwiler BH, Thompson SM.
    J Neurosci; 1997 Oct 01; 17(19):7190-202. PubMed ID: 9295365
    [Abstract] [Full Text] [Related]

  • 7. [Action mechanisms of botulinum neurotoxins and tetanus neurotoxins].
    Deloye F, Doussau F, Poulain B.
    C R Seances Soc Biol Fil; 1997 Oct 01; 191(3):433-50. PubMed ID: 9295967
    [Abstract] [Full Text] [Related]

  • 8. Alpha-latrotoxin rescues SNAP-25 from BoNT/A-mediated proteolysis in embryonic stem cell-derived neurons.
    Mesngon M, McNutt P.
    Toxins (Basel); 2011 May 01; 3(5):489-503. PubMed ID: 22069721
    [Abstract] [Full Text] [Related]

  • 9. In vitro and ex vivo screening of candidate therapeutics to restore neurotransmission in nerve terminals intoxicated by botulinum neurotoxin serotype A1.
    Beske PH, Bradford AB, Hoffman KM, Mason SJ, McNutt PM.
    Toxicon; 2018 Jun 01; 147():47-53. PubMed ID: 29054436
    [Abstract] [Full Text] [Related]

  • 10. [Analysis of synaptic neurotransmitter release mechanisms using bacterial toxins].
    Doussau F, Humeau Y, Vitiello F, Popoff MR, Poulain B.
    J Soc Biol; 1999 Jun 01; 193(6):457-67. PubMed ID: 10783704
    [Abstract] [Full Text] [Related]

  • 11. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 12. Effects of tetanus toxin on spontaneous and evoked transmitter release at inhibitory and excitatory synapses in the rat SDCN neurons.
    Shin MC, Nonaka K, Wakita M, Yamaga T, Torii Y, Harakawa T, Ginnaga A, Ito Y, Akaike N.
    Toxicon; 2012 Mar 01; 59(3):385-92. PubMed ID: 22227157
    [Abstract] [Full Text] [Related]

  • 13. Distinct effects of clostridial toxins on activity-dependent modulation of autaptic responses in cultured hippocampal neurons.
    Owe-Larsson B, Kristensson K, Hill RH, Brodin L.
    Eur J Neurosci; 1997 Aug 01; 9(8):1773-7. PubMed ID: 9283832
    [Abstract] [Full Text] [Related]

  • 14. Botulinum A neurotoxin unlike tetanus toxin acts via a neuraminidase sensitive structure.
    Bigalke H, Müller H, Dreyer F.
    Toxicon; 1986 Aug 01; 24(11-12):1065-74. PubMed ID: 3564058
    [Abstract] [Full Text] [Related]

  • 15. Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discovery.
    Kiris E, Nuss JE, Burnett JC, Kota KP, Koh DC, Wanner LM, Torres-Melendez E, Gussio R, Tessarollo L, Bavari S.
    Stem Cell Res; 2011 May 01; 6(3):195-205. PubMed ID: 21353660
    [Abstract] [Full Text] [Related]

  • 16. Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses.
    Pellizzari R, Rossetto O, Schiavo G, Montecucco C.
    Philos Trans R Soc Lond B Biol Sci; 1999 Feb 28; 354(1381):259-68. PubMed ID: 10212474
    [Abstract] [Full Text] [Related]

  • 17. Botulinum A neurotoxin inhibits non-cholinergic synaptic transmission in mouse spinal cord neurons in culture.
    Bigalke H, Dreyer F, Bergey G.
    Brain Res; 1985 Dec 23; 360(1-2):318-24. PubMed ID: 3000532
    [Abstract] [Full Text] [Related]

  • 18. Uptake of botulinum neurotoxin into cultured neurons.
    Keller JE, Cai F, Neale EA.
    Biochemistry; 2004 Jan 20; 43(2):526-32. PubMed ID: 14717608
    [Abstract] [Full Text] [Related]

  • 19. Botulinum neurotoxins: mechanism of action.
    Tighe AP, Schiavo G.
    Toxicon; 2013 Jun 01; 67():87-93. PubMed ID: 23201505
    [Abstract] [Full Text] [Related]

  • 20. Synaptic structural modification following changes in activity induced by tetanus neurotoxin in cat abducens neurons.
    González-Forero D, Pastor AM, Delgado-García JM, de la Cruz RR, Alvarez FJ.
    J Comp Neurol; 2004 Mar 29; 471(2):201-18. PubMed ID: 14986313
    [Abstract] [Full Text] [Related]


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