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Journal Abstract Search

138 related items for PubMed ID: 25746794

  • 1. An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics.
    Reed DM, Paschalaki KE, Starke RD, Mohamed NA, Sharp G, Fox B, Eastwood D, Bristow A, Ball C, Vessillier S, Hansel TT, Thorpe SJ, Randi AM, Stebbings R, Mitchell JA.
    FASEB J; 2015 Jun; 29(6):2595-602. PubMed ID: 25746794
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  • 3. A simple whole blood bioassay detects cytokine responses to anti-CD28SA and anti-CD52 antibodies.
    Bailey L, Moreno L, Manigold T, Krasniqi S, Kropshofer H, Hinton H, Singer T, Suter L, Hansel TT, Mitchell JA.
    J Pharmacol Toxicol Methods; 2013 Jun; 68(2):231-239. PubMed ID: 23280407
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  • 4. A predictive biomimetic model of cytokine release induced by TGN1412 and other therapeutic monoclonal antibodies.
    Dhir V, Fort M, Mahmood A, Higbee R, Warren W, Narayanan P, Wittman V.
    J Immunotoxicol; 2012 Jun; 9(1):34-42. PubMed ID: 22074378
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  • 5. Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials--Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm.
    Vessillier S, Eastwood D, Fox B, Sathish J, Sethu S, Dougall T, Thorpe SJ, Thorpe R, Stebbings R.
    J Immunol Methods; 2015 Sep; 424():43-52. PubMed ID: 25960173
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  • 6. Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412.
    Findlay L, Eastwood D, Stebbings R, Sharp G, Mistry Y, Ball C, Hood J, Thorpe R, Poole S.
    J Immunol Methods; 2010 Jan 31; 352(1-2):1-12. PubMed ID: 19895813
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  • 10. Severity of the TGN1412 trial disaster cytokine storm correlated with IL-2 release.
    Eastwood D, Bird C, Dilger P, Hockley J, Findlay L, Poole S, Thorpe SJ, Wadhwa M, Thorpe R, Stebbings R.
    Br J Clin Pharmacol; 2013 Aug 31; 76(2):299-315. PubMed ID: 23701319
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  • 11. A bioassay system of autologous human endothelial, smooth muscle cells, and leukocytes for use in drug discovery, phenotyping, and tissue engineering.
    Ahmetaj-Shala B, Kawai R, Marei I, Nikolakopoulou Z, Shih CC, Konain B, Reed DM, Mongey R, Kirkby NS, Mitchell JA.
    FASEB J; 2020 Jan 31; 34(1):1745-1754. PubMed ID: 31914612
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  • 15. After TGN1412: recent developments in cytokine release assays.
    Stebbings R, Eastwood D, Poole S, Thorpe R.
    J Immunotoxicol; 2013 Jan 31; 10(1):75-82. PubMed ID: 22967038
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  • 16. Cytokines and vascular permeability: an in vitro study on human endothelial cells in relation to tumor necrosis factor-alpha-primed peripheral blood mononuclear cells.
    Seynhaeve AL, Vermeulen CE, Eggermont AM, ten Hagen TL.
    Cell Biochem Biophys; 2006 Jan 31; 44(1):157-69. PubMed ID: 16456244
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  • 17. Cytokine-mediated effects of peripheral blood mononuclear cells from patients with atopic eczema on keratinocytes (HaCaT) in a new coculture system.
    Neuber K, Steinrücke K, Kowalzick L, Köhler I, Ring J.
    Br J Dermatol; 1995 Nov 31; 133(5):750-6. PubMed ID: 8555028
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  • 18. Anti-class II -DR humanized monoclonal antibody, IMMU-114, blocks allogeneic immune response.
    Park KH, Sawada T, Murakami T, Ishii Y, Yasuo M, Fuchinoue S, Goldenberg DM, Kubota K.
    Am J Surg; 2012 Oct 31; 204(4):527-34. PubMed ID: 22658578
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  • 19. The blood endothelial cell chamber - An innovative system to study immune responses in drug development.
    Stančič B, Qvarfordt B, Berglund MM, Brenden N, Sydow Bäckman M, Fransson M, Nordling S, Magnusson PU.
    Int Immunopharmacol; 2021 Jan 31; 90():107237. PubMed ID: 33310662
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  • 20. Antibody C region influences TGN1412-like functional activity in vitro.
    Ball C, Fox B, Hufton S, Sharp G, Poole S, Stebbings R, Eastwood D, Findlay L, Parren PW, Thorpe R, Bristow A, Thorpe SJ.
    J Immunol; 2012 Dec 15; 189(12):5831-40. PubMed ID: 23150712
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