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Journal Abstract Search

160 related items for PubMed ID: 25750987

  • 1. Synthesis and evaluation of hydroxymethylaminocyclitols as glycosidase inhibitors.
    Trapero A, Egido-Gabás M, Bujons J, Llebaria A.
    J Org Chem; 2015 Apr 03; 80(7):3512-29. PubMed ID: 25750987
    [Abstract] [Full Text] [Related]

  • 2. Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors.
    Li KY, Jiang J, Witte MD, Kallemeijn WW, Donker-Koopman WE, Boot RG, Aerts JM, Codée JD, van der Marel GA, Overkleeft HS.
    Org Biomol Chem; 2014 Oct 21; 12(39):7786-91. PubMed ID: 25156485
    [Abstract] [Full Text] [Related]

  • 3. New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening.
    Díaz L, Casas J, Bujons J, Llebaria A, Delgado A.
    J Med Chem; 2011 Apr 14; 54(7):2069-79. PubMed ID: 21370884
    [Abstract] [Full Text] [Related]

  • 4. Potent aminocyclitol glucocerebrosidase inhibitors are subnanomolar pharmacological chaperones for treating gaucher disease.
    Trapero A, González-Bulnes P, Butters TD, Llebaria A.
    J Med Chem; 2012 May 10; 55(9):4479-88. PubMed ID: 22512696
    [Abstract] [Full Text] [Related]

  • 5. Computational prediction of structure-activity relationships for the binding of aminocyclitols to β-glucocerebrosidase.
    Díaz L, Bujons J, Delgado A, Gutiérrez-de-Terán H, Åqvist J.
    J Chem Inf Model; 2011 Mar 28; 51(3):601-11. PubMed ID: 21384831
    [Abstract] [Full Text] [Related]

  • 6. In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling.
    Kuo CL, Kallemeijn WW, Lelieveld LT, Mirzaian M, Zoutendijk I, Vardi A, Futerman AH, Meijer AH, Spaink HP, Overkleeft HS, Aerts JMFG, Artola M.
    FEBS J; 2019 Feb 28; 286(3):584-600. PubMed ID: 30600575
    [Abstract] [Full Text] [Related]

  • 7. Click chemistry approach to new N-substituted aminocyclitols as potential pharmacological chaperones for Gaucher disease.
    Díaz L, Bujons J, Casas J, Llebaria A, Delgado A.
    J Med Chem; 2010 Jul 22; 53(14):5248-55. PubMed ID: 20557054
    [Abstract] [Full Text] [Related]

  • 8. Five-membered iminocyclitol α-glucosidase inhibitors: synthetic, biological screening and in silico studies.
    Guerreiro LR, Carreiro EP, Fernandes L, Cardote TA, Moreira R, Caldeira AT, Guedes RC, Burke AJ.
    Bioorg Med Chem; 2013 Apr 01; 21(7):1911-7. PubMed ID: 23419323
    [Abstract] [Full Text] [Related]

  • 9. Biological properties of D- and L-1-deoxyazasugars.
    Kato A, Kato N, Kano E, Adachi I, Ikeda K, Yu L, Okamoto T, Banba Y, Ouchi H, Takahata H, Asano N.
    J Med Chem; 2005 Mar 24; 48(6):2036-44. PubMed ID: 15771446
    [Abstract] [Full Text] [Related]

  • 10. A short synthesis of (+)-cyclophellitol.
    Hansen FG, Bundgaard E, Madsen R.
    J Org Chem; 2005 Nov 25; 70(24):10139-42. PubMed ID: 16292857
    [Abstract] [Full Text] [Related]

  • 11. Xylose-Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase.
    Su Q, Schröder SP, Lelieveld LT, Ferraz MJ, Verhoek M, Boot RG, Overkleeft HS, Aerts JMFG, Artola M, Kuo CL.
    Chembiochem; 2021 Nov 03; 22(21):3090-3098. PubMed ID: 34459538
    [Abstract] [Full Text] [Related]

  • 12. Biological activities of cyclophellitol.
    Atsumi S, Iinuma H, Nosaka C, Umezawa K.
    J Antibiot (Tokyo); 1990 Dec 03; 43(12):1579-85. PubMed ID: 2148935
    [Abstract] [Full Text] [Related]

  • 13. Structural basis for cyclophellitol inhibition of a beta-glucosidase.
    Gloster TM, Madsen R, Davies GJ.
    Org Biomol Chem; 2007 Feb 07; 5(3):444-6. PubMed ID: 17252125
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice.
    Atsumi S, Nosaka C, Iinuma H, Umezawa K.
    Arch Biochem Biophys; 1992 Sep 07; 297(2):362-7. PubMed ID: 1386724
    [Abstract] [Full Text] [Related]

  • 15. N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.
    Désiré J, Mondon M, Fontelle N, Nakagawa S, Hirokami Y, Adachi I, Iwaki R, Fleet GW, Alonzi DS, Twigg G, Butters TD, Bertrand J, Cendret V, Becq F, Norez C, Marrot J, Kato A, Blériot Y.
    Org Biomol Chem; 2014 Nov 28; 12(44):8977-96. PubMed ID: 25277226
    [Abstract] [Full Text] [Related]

  • 16. Chemoenzymatic synthesis of 6-phospho-cyclophellitol as a novel probe of 6-phospho-β-glucosidases.
    Kwan DH, Jin Y, Jiang J, Chen HM, Kötzler MP, Overkleeft HS, Davies GJ, Withers SG.
    FEBS Lett; 2016 Feb 28; 590(4):461-8. PubMed ID: 26790390
    [Abstract] [Full Text] [Related]

  • 17. Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring.
    Aguilar-Moncayo M, Gloster TM, Turkenburg JP, García-Moreno MI, Ortiz Mellet C, Davies GJ, García Fernández JM.
    Org Biomol Chem; 2009 Jul 07; 7(13):2738-47. PubMed ID: 19532990
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of experimental metastasis by an alpha-glucosidase inhibitor, 1,6-epi-cyclophellitol.
    Atsumi S, Nosaka C, Ochi Y, Iinuma H, Umezawa K.
    Cancer Res; 1993 Oct 15; 53(20):4896-9. PubMed ID: 8402678
    [Abstract] [Full Text] [Related]

  • 19. Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
    Asano N, Nishida M, Kato A, Kizu H, Matsui K, Shimada Y, Itoh T, Baba M, Watson AA, Nash RJ, Lilley PM, Watkin DJ, Fleet GW.
    J Med Chem; 1998 Jul 02; 41(14):2565-71. PubMed ID: 9651160
    [Abstract] [Full Text] [Related]

  • 20. Voglibose-inspired synthesis of new potent α-glucosidase inhibitors N-1,3-dihydroxypropylaminocyclitols.
    Worawalai W, Sompornpisut P, Wacharasindhu S, Phuwapraisirisan P.
    Carbohydr Res; 2016 Jun 24; 429():155-62. PubMed ID: 27140506
    [Abstract] [Full Text] [Related]

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