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461 related items for PubMed ID: 25752454

  • 1. mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
    Nguyen LH, Brewster AL, Clark ME, Regnier-Golanov A, Sunnen CN, Patil VV, D'Arcangelo G, Anderson AE.
    Epilepsia; 2015 Apr; 56(4):636-46. PubMed ID: 25752454
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  • 3. Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice.
    Sunnen CN, Brewster AL, Lugo JN, Vanegas F, Turcios E, Mukhi S, Parghi D, D'Arcangelo G, Anderson AE.
    Epilepsia; 2011 Nov; 52(11):2065-75. PubMed ID: 21973019
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  • 4. Rapamycin improves social and stereotypic behavior abnormalities induced by pre-mitotic neuronal subset specific Pten deletion.
    Narvaiz DA, Nolan SO, Smith GD, Holley AJ, Reynolds CD, Blandin KJ, Nguyen PH, Tran DLK, Lugo JN.
    Genes Brain Behav; 2023 Aug; 22(4):e12854. PubMed ID: 37376966
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  • 5. Targeting the Mammalian Target of Rapamycin for Epileptic Encephalopathies and Malformations of Cortical Development.
    Jeong A, Wong M.
    J Child Neurol; 2018 Jan; 33(1):55-63. PubMed ID: 29246093
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  • 6. Commentary: mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
    Wong M.
    Epilepsia; 2016 Sep; 57(9):1349-50. PubMed ID: 27522175
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  • 7. mTOR Hyperactivity Levels Influence the Severity of Epilepsy and Associated Neuropathology in an Experimental Model of Tuberous Sclerosis Complex and Focal Cortical Dysplasia.
    Nguyen LH, Mahadeo T, Bordey A.
    J Neurosci; 2019 Apr 03; 39(14):2762-2773. PubMed ID: 30700531
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  • 12. mTOR pathway inhibition as a new therapeutic strategy in epilepsy and epileptogenesis.
    Citraro R, Leo A, Constanti A, Russo E, De Sarro G.
    Pharmacol Res; 2016 May 03; 107():333-343. PubMed ID: 27049136
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  • 13. Inhibition of mammalian target of rapamycin with rapamycin reverses hypertrophic cardiomyopathy in mice with cardiomyocyte-specific knockout of PTEN.
    Xu X, Roe ND, Weiser-Evans MC, Ren J.
    Hypertension; 2014 Apr 03; 63(4):729-39. PubMed ID: 24446058
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  • 14. Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
    LaSarge CL, Pun RYK, Gu Z, Santos VR, Danzer SC.
    Exp Neurol; 2019 Nov 03; 321():113029. PubMed ID: 31377403
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  • 15. Intermittent dosing of rapamycin maintains antiepileptogenic effects in a mouse model of tuberous sclerosis complex.
    Rensing N, Han L, Wong M.
    Epilepsia; 2015 Jul 03; 56(7):1088-97. PubMed ID: 26122303
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  • 16. Hypervascularization in mTOR-dependent focal and global cortical malformations displays differential rapamycin sensitivity.
    Zhang L, Huang T, Teaw S, Bordey A.
    Epilepsia; 2019 Jun 03; 60(6):1255-1265. PubMed ID: 31125447
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  • 18. Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons.
    Getz SA, DeSpenza T, Li M, Luikart BW.
    Neurobiol Dis; 2016 Sep 03; 93():12-20. PubMed ID: 26992888
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  • 20. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility.
    Yuskaitis CJ, Jones BM, Wolfson RL, Super CE, Dhamne SC, Rotenberg A, Sabatini DM, Sahin M, Poduri A.
    Neurobiol Dis; 2018 Mar 03; 111():91-101. PubMed ID: 29274432
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