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9. APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer's mice via cyclophilin A independently of amyloid-β. Montagne A, Nikolakopoulou AM, Huuskonen MT, Sagare AP, Lawson EJ, Lazic D, Rege SV, Grond A, Zuniga E, Barnes SR, Prince J, Sagare M, Hsu CJ, LaDu MJ, Jacobs RE, Zlokovic BV. Nat Aging; 2021 Jun 19; 1(6):506-520. PubMed ID: 35291561 [Abstract] [Full Text] [Related]
10. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV. J Clin Invest; 2008 Dec 19; 118(12):4002-13. PubMed ID: 19033669 [Abstract] [Full Text] [Related]
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12. Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Nat Med; 2020 Jun 19; 26(6):952-963. PubMed ID: 32514169 [Abstract] [Full Text] [Related]
13. LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. Oue H, Yamazaki Y, Qiao W, Yuanxin C, Ren Y, Kurti A, Shue F, Parsons TM, Perkerson RB, Kawatani K, Wang N, Starling SC, Roy B, Mosneag IE, Aikawa T, Holm ML, Liu CC, Inoue Y, Sullivan PM, Asmann YW, Kim BY, Bu G, Kanekiyo T. JCI Insight; 2023 Apr 10; 8(7):. PubMed ID: 37036005 [Abstract] [Full Text] [Related]
14. ApoE4-mediated blood-brain barrier damage in Alzheimer's disease: Progress and prospects. Zhou X, Shi Q, Zhang X, Gu L, Li J, Quan S, Zhao X, Li Q. Brain Res Bull; 2023 Jul 10; 199():110670. PubMed ID: 37224887 [Abstract] [Full Text] [Related]
15. Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease. Sengillo JD, Winkler EA, Walker CT, Sullivan JS, Johnson M, Zlokovic BV. Brain Pathol; 2013 May 10; 23(3):303-10. PubMed ID: 23126372 [Abstract] [Full Text] [Related]
16. In Thai Nationals, the ApoE4 Allele Affects Multiple Domains of Neuropsychological, Biobehavioral, and Social Functioning Thereby Contributing to Alzheimer's Disorder, while the ApoE3 Allele Protects Against Neuropsychiatric Symptoms and Psychosocial Deficits. Tangwongchai S, Supasitthumrong T, Hemrunroj S, Tunvirachaisakul C, Chuchuen P, Houngngam N, Snabboon T, Tawankanjanachot I, Likitchareon Y, Phanthumchindad K, Maes M. Mol Neurobiol; 2018 Aug 10; 55(8):6449-6462. PubMed ID: 29307083 [Abstract] [Full Text] [Related]
17. Impairment of pericyte-endothelium crosstalk leads to blood-brain barrier dysfunction following traumatic brain injury. Bhowmick S, D'Mello V, Caruso D, Wallerstein A, Abdul-Muneer PM. Exp Neurol; 2019 Jul 10; 317():260-270. PubMed ID: 30926390 [Abstract] [Full Text] [Related]
18. Disruption of Bmal1 Impairs Blood-Brain Barrier Integrity via Pericyte Dysfunction. Nakazato R, Kawabe K, Yamada D, Ikeno S, Mieda M, Shimba S, Hinoi E, Yoneda Y, Takarada T. J Neurosci; 2017 Oct 18; 37(42):10052-10062. PubMed ID: 28912161 [Abstract] [Full Text] [Related]
19. Little genomic support for Cyclophilin A-matrix metalloproteinase-9 pathway as a therapeutic target for cognitive impairment in APOE4 carriers. Anderson EL, Williams DM, Walker VM, Davies NM. Sci Rep; 2022 Jan 20; 12(1):1057. PubMed ID: 35058547 [Abstract] [Full Text] [Related]
20. Effect of Vascular Risk Factors on Blood-Brain Barrier and Cerebrospinal Fluid Biomarkers Along the Alzheimer's Disease Continuum: A Retrospective Observational Study. Ricci F, Martorana A, Bonomi CG, Serafini C, Mercuri NB, Koch G, Motta C. J Alzheimers Dis; 2024 Jan 20; 97(2):599-607. PubMed ID: 38160356 [Abstract] [Full Text] [Related] Page: [Next] [New Search]