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356 related items for PubMed ID: 25763681
1. Uncovering the formation and selection of benzylmalonyl-CoA from the biosynthesis of splenocin and enterocin reveals a versatile way to introduce amino acids into polyketide carbon scaffolds. Chang C, Huang R, Yan Y, Ma H, Dai Z, Zhang B, Deng Z, Liu W, Qu X. J Am Chem Soc; 2015 Apr 01; 137(12):4183-90. PubMed ID: 25763681 [Abstract] [Full Text] [Related]
2. Structural Basis of a Broadly Selective Acyltransferase from the Polyketide Synthase of Splenocin. Li Y, Zhang W, Zhang H, Tian W, Wu L, Wang S, Zheng M, Zhang J, Sun C, Deng Z, Sun Y, Qu X, Zhou J. Angew Chem Int Ed Engl; 2018 May 14; 57(20):5823-5827. PubMed ID: 29536601 [Abstract] [Full Text] [Related]
3. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit. Miyazawa T, Takahashi S, Kawata A, Panthee S, Hayashi T, Shimizu T, Nogawa T, Osada H. J Biol Chem; 2015 Nov 06; 290(45):26994-27011. PubMed ID: 26378232 [Abstract] [Full Text] [Related]
4. A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units. Ray L, Valentic TR, Miyazawa T, Withall DM, Song L, Milligan JC, Osada H, Takahashi S, Tsai SC, Challis GL. Nat Commun; 2016 Dec 21; 7():13609. PubMed ID: 28000660 [Abstract] [Full Text] [Related]
5. Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis. Zhang L, Mori T, Zheng Q, Awakawa T, Yan Y, Liu W, Abe I. Angew Chem Int Ed Engl; 2015 Nov 02; 54(45):13462-5. PubMed ID: 26356484 [Abstract] [Full Text] [Related]
6. Exploring the Promiscuous Enzymatic Activation of Unnatural Polyketide Extender Units in Vitro and in Vivo for Monensin Biosynthesis. Grote M, Schulz F. Chembiochem; 2019 May 02; 20(9):1183-1189. PubMed ID: 30629783 [Abstract] [Full Text] [Related]
7. Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase. Zhang F, Shi T, Ji H, Ali I, Huang S, Deng Z, Min Q, Bai L, Zhao Y, Zheng J. Biochemistry; 2019 Jul 09; 58(27):2978-2986. PubMed ID: 31199122 [Abstract] [Full Text] [Related]
8. Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway. Möller D, Kushnir S, Grote M, Ismail-Ali A, Koopmans KRM, Calo F, Heinrich S, Diehl B, Schulz F. Lett Appl Microbiol; 2018 Sep 09; 67(3):226-234. PubMed ID: 29927502 [Abstract] [Full Text] [Related]
9. Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB. Hughes AJ, Keatinge-Clay A. Chem Biol; 2011 Feb 25; 18(2):165-76. PubMed ID: 21338915 [Abstract] [Full Text] [Related]
10. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases. Dunn BJ, Watts KR, Robbins T, Cane DE, Khosla C. Biochemistry; 2014 Jun 17; 53(23):3796-806. PubMed ID: 24871074 [Abstract] [Full Text] [Related]
11. Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli. Kalkreuter E, Keeler AM, Malico AA, Bingham KS, Gayen AK, Williams GJ. ACS Synth Biol; 2019 Jun 21; 8(6):1391-1400. PubMed ID: 31134799 [Abstract] [Full Text] [Related]
12. The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. Musiol EM, Greule A, Härtner T, Kulik A, Wohlleben W, Weber T. Chembiochem; 2013 Jul 22; 14(11):1343-52. PubMed ID: 23828654 [Abstract] [Full Text] [Related]
13. Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS. Musiol EM, Härtner T, Kulik A, Moldenhauer J, Piel J, Wohlleben W, Weber T. Chem Biol; 2011 Apr 22; 18(4):438-44. PubMed ID: 21513880 [Abstract] [Full Text] [Related]
14. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. Mo S, Kim DH, Lee JH, Park JW, Basnet DB, Ban YH, Yoo YJ, Chen SW, Park SR, Choi EA, Kim E, Jin YY, Lee SK, Park JY, Liu Y, Lee MO, Lee KS, Kim SJ, Kim D, Park BC, Lee SG, Kwon HJ, Suh JW, Moore BS, Lim SK, Yoon YJ. J Am Chem Soc; 2011 Feb 02; 133(4):976-85. PubMed ID: 21175203 [Abstract] [Full Text] [Related]
15. Biochemical characterization of a malonyl-specific acyltransferase domain of FK506 biosynthetic polyketide synthase. Wang YY, Bai LF, Ran XX, Jiang XH, Wu H, Zhang W, Jin MY, Li YQ, Jiang H. Protein Pept Lett; 2015 Feb 02; 22(1):2-7. PubMed ID: 25267255 [Abstract] [Full Text] [Related]
16. Combining Promiscuous Acyl-CoA Oxidase and Enoyl-CoA Carboxylase/Reductases for Atypical Polyketide Extender Unit Biosynthesis. Vögeli B, Geyer K, Gerlinger PD, Benkstein S, Cortina NS, Erb TJ. Cell Chem Biol; 2018 Jul 19; 25(7):833-839.e4. PubMed ID: 29731424 [Abstract] [Full Text] [Related]
17. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. Koryakina I, Kasey C, McArthur JB, Lowell AN, Chemler JA, Li S, Hansen DA, Sherman DH, Williams GJ. ACS Chem Biol; 2017 Jan 20; 12(1):114-123. PubMed ID: 28103677 [Abstract] [Full Text] [Related]
18. Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units. Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z. J Biol Chem; 2010 Jun 25; 285(26):20097-108. PubMed ID: 20406823 [Abstract] [Full Text] [Related]
19. Structural and computational insights into the substrate specificity of acyltransferase domains from modular polyketide synthases. Huang S, Ji H, Zheng J. FEBS J; 2024 Sep 25; 291(17):3839-3855. PubMed ID: 38922792 [Abstract] [Full Text] [Related]
20. Poly specific trans-acyltransferase machinery revealed via engineered acyl-CoA synthetases. Koryakina I, McArthur J, Randall S, Draelos MM, Musiol EM, Muddiman DC, Weber T, Williams GJ. ACS Chem Biol; 2013 Jan 18; 8(1):200-8. PubMed ID: 23083014 [Abstract] [Full Text] [Related] Page: [Next] [New Search]