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Journal Abstract Search

275 related items for PubMed ID: 25768649

  • 1. Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.
    Bialas J, Groettrup M, Aichem A.
    PLoS One; 2015; 10(3):e0120329. PubMed ID: 25768649
    [Abstract] [Full Text] [Related]

  • 2. Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1.
    Aichem A, Catone N, Groettrup M.
    FEBS J; 2014 Apr; 281(7):1848-59. PubMed ID: 24528925
    [Abstract] [Full Text] [Related]

  • 3. UBA6 and Its Bispecific Pathways for Ubiquitin and FAT10.
    Wang F, Zhao B.
    Int J Mol Sci; 2019 May 07; 20(9):. PubMed ID: 31067743
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  • 5. LMO2 blocks the UBA6-USE1 interaction and downstream FAT10ylation by targeting the ubiquitin fold domain of UBA6.
    Wu C, Liu Y, Gu X, Zhu T, Yang S, Sun W.
    Biochem Biophys Res Commun; 2016 Sep 23; 478(3):1442-8. PubMed ID: 27569286
    [Abstract] [Full Text] [Related]

  • 6. FAT10 : Activated by UBA6 and Functioning in Protein Degradation.
    Pelzer C, Groettrup M.
    Subcell Biochem; 2010 Sep 23; 54():238-46. PubMed ID: 21222287
    [Abstract] [Full Text] [Related]

  • 7. FAT10ylation as a signal for proteasomal degradation.
    Schmidtke G, Aichem A, Groettrup M.
    Biochim Biophys Acta; 2014 Jan 23; 1843(1):97-102. PubMed ID: 23333871
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  • 9. USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis.
    Aichem A, Pelzer C, Lukasiak S, Kalveram B, Sheppard PW, Rani N, Schmidtke G, Groettrup M.
    Nat Commun; 2010 May 04; 1():13. PubMed ID: 20975683
    [Abstract] [Full Text] [Related]

  • 10. The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.
    Aichem A, Anders S, Catone N, Rößler P, Stotz S, Berg A, Schwab R, Scheuermann S, Bialas J, Schütz-Stoffregen MC, Schmidtke G, Peter C, Groettrup M, Wiesner S.
    Nat Commun; 2018 Aug 20; 9(1):3321. PubMed ID: 30127417
    [Abstract] [Full Text] [Related]

  • 11. The ubiquitin-like modifier FAT10 interferes with SUMO activation.
    Aichem A, Sailer C, Ryu S, Catone N, Stankovic-Valentin N, Schmidtke G, Melchior F, Stengel F, Groettrup M.
    Nat Commun; 2019 Oct 01; 10(1):4452. PubMed ID: 31575873
    [Abstract] [Full Text] [Related]

  • 12. The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1.
    Bialas J, Boehm AN, Catone N, Aichem A, Groettrup M.
    J Biol Chem; 2019 Mar 22; 294(12):4315-4330. PubMed ID: 30718280
    [Abstract] [Full Text] [Related]

  • 13. Tumor necrosis factor mediates USE1-independent FAT10ylation under inflammatory conditions.
    Schnell L, Zubrod A, Catone N, Bialas J, Aichem A.
    Life Sci Alliance; 2023 Nov 22; 6(11):. PubMed ID: 37604583
    [Abstract] [Full Text] [Related]

  • 14. Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.
    Gavin JM, Chen JJ, Liao H, Rollins N, Yang X, Xu Q, Ma J, Loke HK, Lingaraj T, Brownell JE, Mallender WD, Gould AE, Amidon BS, Dick LR.
    J Biol Chem; 2012 May 04; 287(19):15512-22. PubMed ID: 22427669
    [Abstract] [Full Text] [Related]

  • 15. Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery.
    Schelpe J, Monté D, Dewitte F, Sixma TK, Rucktooa P.
    J Biol Chem; 2016 Jan 08; 291(2):630-9. PubMed ID: 26555268
    [Abstract] [Full Text] [Related]

  • 16. The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation.
    Boehm AN, Bialas J, Catone N, Sacristan-Reviriego A, van der Spuy J, Groettrup M, Aichem A.
    J Biol Chem; 2020 Oct 16; 295(42):14402-14418. PubMed ID: 32817338
    [Abstract] [Full Text] [Related]

  • 17. Analysis of modification and proteolytic targeting by the ubiquitin-like modifier FAT10.
    Aichem A, Boehm AN, Catone N, Schmidtke G, Groettrup M.
    Methods Enzymol; 2019 Oct 16; 618():229-256. PubMed ID: 30850054
    [Abstract] [Full Text] [Related]

  • 18. Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
    Truongvan N, Li S, Misra M, Kuhn M, Schindelin H.
    Nat Commun; 2022 Aug 15; 13(1):4789. PubMed ID: 35970836
    [Abstract] [Full Text] [Related]

  • 19. Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.
    Jin J, Li X, Gygi SP, Harper JW.
    Nature; 2007 Jun 28; 447(7148):1135-8. PubMed ID: 17597759
    [Abstract] [Full Text] [Related]

  • 20. Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy.
    Roverato ND, Sailer C, Catone N, Aichem A, Stengel F, Groettrup M.
    Cell Rep; 2021 Mar 16; 34(11):108857. PubMed ID: 33730565
    [Abstract] [Full Text] [Related]

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