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Journal Abstract Search

714 related items for PubMed ID: 25779942

  • 1. SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma.
    Tang SW, Bilke S, Cao L, Murai J, Sousa FG, Yamade M, Rajapakse V, Varma S, Helman LJ, Khan J, Meltzer PS, Pommier Y.
    Clin Cancer Res; 2015 Sep 15; 21(18):4184-93. PubMed ID: 25779942
    [Abstract] [Full Text] [Related]

  • 2. Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
    Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schäfer BW, Niggli FK.
    J Biol Chem; 2016 Dec 23; 291(52):26922-26933. PubMed ID: 27875302
    [Abstract] [Full Text] [Related]

  • 3. EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.
    Jiménez JA, Apfelbaum AA, Hawkins AG, Svoboda LK, Kumar A, Ruiz RO, Garcia AX, Haarer E, Nwosu ZC, Bradin J, Purohit T, Chen D, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.
    Mol Cancer Res; 2021 Jul 23; 19(7):1182-1195. PubMed ID: 33741715
    [Abstract] [Full Text] [Related]

  • 4. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
    Hensel T, Giorgi C, Schmidt O, Calzada-Wack J, Neff F, Buch T, Niggli FK, Schäfer BW, Burdach S, Richter GH.
    Oncotarget; 2016 Jan 12; 7(2):1451-63. PubMed ID: 26623725
    [Abstract] [Full Text] [Related]

  • 5. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.
    Niedan S, Kauer M, Aryee DN, Kofler R, Schwentner R, Meier A, Pötschger U, Kontny U, Kovar H.
    Oncogene; 2014 Jul 24; 33(30):3927-38. PubMed ID: 23995784
    [Abstract] [Full Text] [Related]

  • 6. SLFN11: Achilles' Heel or Troublemaker.
    Kovar H.
    Clin Cancer Res; 2015 Sep 15; 21(18):4033-4. PubMed ID: 26034126
    [Abstract] [Full Text] [Related]

  • 7. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.
    Giorgi C, Boro A, Rechfeld F, Lopez-Garcia LA, Gierisch ME, Schäfer BW, Niggli FK.
    Oncotarget; 2015 Oct 06; 6(30):28895-910. PubMed ID: 26336820
    [Abstract] [Full Text] [Related]

  • 8. EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.
    Cidre-Aranaz F, Grünewald TG, Surdez D, García-García L, Carlos Lázaro J, Kirchner T, González-González L, Sastre A, García-Miguel P, López-Pérez SE, Monzón S, Delattre O, Alonso J.
    Oncogene; 2017 Feb 09; 36(6):766-776. PubMed ID: 27375017
    [Abstract] [Full Text] [Related]

  • 9. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.
    He T, Surdez D, Rantala JK, Haapa-Paananen S, Ban J, Kauer M, Tomazou E, Fey V, Alonso J, Kovar H, Delattre O, Iljin K.
    Gene; 2017 Jan 05; 596():137-146. PubMed ID: 27760381
    [Abstract] [Full Text] [Related]

  • 10. Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.
    Grohar PJ, Segars LE, Yeung C, Pommier Y, D'Incalci M, Mendoza A, Helman LJ.
    Clin Cancer Res; 2014 Mar 01; 20(5):1190-203. PubMed ID: 24277455
    [Abstract] [Full Text] [Related]

  • 11. EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma.
    Shimizu R, Tanaka M, Tsutsumi S, Aburatani H, Yamazaki Y, Homme M, Kitagawa Y, Nakamura T.
    Cancer Sci; 2018 Sep 01; 109(9):2907-2918. PubMed ID: 29945296
    [Abstract] [Full Text] [Related]

  • 12. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
    Boro A, Prêtre K, Rechfeld F, Thalhammer V, Oesch S, Wachtel M, Schäfer BW, Niggli FK.
    Int J Cancer; 2012 Nov 01; 131(9):2153-64. PubMed ID: 22323082
    [Abstract] [Full Text] [Related]

  • 13. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J.
    Oncotarget; 2016 Jul 12; 7(28):43504-43517. PubMed ID: 27259270
    [Abstract] [Full Text] [Related]

  • 14. MiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumor.
    Franzetti GA, Laud-Duval K, Bellanger D, Stern MH, Sastre-Garau X, Delattre O.
    Oncogene; 2013 Aug 15; 32(33):3915-21. PubMed ID: 22986530
    [Abstract] [Full Text] [Related]

  • 15. EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
    Apfelbaum AA, Wu F, Hawkins AG, Magnuson B, Jiménez JA, Taylor SD, Wrenn ED, Waltner O, Pfaltzgraff ER, Song JY, Hall C, Wellik DM, Ljungman M, Furlan SN, Ryan RJH, Sarthy JF, Lawlor ER.
    Clin Cancer Res; 2022 Oct 14; 28(20):4466-4478. PubMed ID: 35653119
    [Abstract] [Full Text] [Related]

  • 16. Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor.
    Osgood CL, Maloney N, Kidd CG, Kitchen-Goosen S, Segars L, Gebregiorgis M, Woldemichael GM, He M, Sankar S, Lessnick SL, Kang M, Smith M, Turner L, Madaj ZB, Winn ME, Núñez LE, González-Sabín J, Helman LJ, Morís F, Grohar PJ.
    Clin Cancer Res; 2016 Aug 15; 22(16):4105-18. PubMed ID: 26979396
    [Abstract] [Full Text] [Related]

  • 17. Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis.
    Ma Y, Baltezor M, Rajewski L, Crow J, Samuel G, Staggs VS, Chastain KM, Toretsky JA, Weir SJ, Godwin AK.
    J Mol Med (Berl); 2019 Jul 15; 97(7):957-972. PubMed ID: 31025088
    [Abstract] [Full Text] [Related]

  • 18. Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.
    Wang S, Huo X, Yang Y, Mo Y, Kollipara RK, Kittler R.
    Cancer Lett; 2023 Jan 01; 552():215984. PubMed ID: 36330954
    [Abstract] [Full Text] [Related]

  • 19. EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.
    Sen N, Cross AM, Lorenzi PL, Khan J, Gryder BE, Kim S, Caplen NJ.
    Mol Carcinog; 2018 Oct 01; 57(10):1342-1357. PubMed ID: 29873416
    [Abstract] [Full Text] [Related]

  • 20. The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.
    Mendiola M, Carrillo J, García E, Lalli E, Hernández T, de Alava E, Tirode F, Delattre O, García-Miguel P, López-Barea F, Pestaña A, Alonso J.
    Int J Cancer; 2006 Mar 15; 118(6):1381-9. PubMed ID: 16206264
    [Abstract] [Full Text] [Related]

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