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221 related items for PubMed ID: 25781377

  • 1. Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
    Chofor R, Sooriyaarachchi S, Risseeuw MD, Bergfors T, Pouyez J, Johny C, Haymond A, Everaert A, Dowd CS, Maes L, Coenye T, Alex A, Couch RD, Jones TA, Wouters J, Mowbray SL, Van Calenbergh S.
    J Med Chem; 2015 Apr 09; 58(7):2988-3001. PubMed ID: 25781377
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  • 3. Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR).
    Abdullaziz MA, Takada S, Illarionov B, Pessanha de Carvalho L, Sakamoto Y, Höfmann S, Knak T, Kiffe-Delf AL, Mazzone F, Pfeffer K, Kalscheuer R, Bacher A, Held J, Fischer M, Tanaka N, Kurz T.
    ACS Infect Dis; 2024 May 10; 10(5):1739-1752. PubMed ID: 38647213
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  • 8. α-Substituted β-oxa isosteres of fosmidomycin: synthesis and biological evaluation.
    Brücher K, Illarionov B, Held J, Tschan S, Kunfermann A, Pein MK, Bacher A, Gräwert T, Maes L, Mordmüller B, Fischer M, Kurz T.
    J Med Chem; 2012 Jul 26; 55(14):6566-75. PubMed ID: 22731758
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  • 14. Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors.
    Haemers T, Wiesner J, Van Poecke S, Goeman J, Henschker D, Beck E, Jomaa H, Van Calenbergh S.
    Bioorg Med Chem Lett; 2006 Apr 01; 16(7):1888-91. PubMed ID: 16439126
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  • 20. 1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors.
    Mazzone F, Hoeppner A, Reiners J, Gertzen CGW, Applegate V, Abdullaziz MA, Gottstein J, Degrandi D, Wesemann M, Kurz T, Smits SHJ, Pfeffer K.
    Biochem J; 2024 Aug 21; 481(16):1075-1096. PubMed ID: 39105673
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