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428 related items for PubMed ID: 25784721

  • 1. Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors.
    Gimenez LE, Baameur F, Vayttaden SJ, Clark RB.
    Mol Pharmacol; 2015 Jun; 87(6):954-64. PubMed ID: 25784721
    [Abstract] [Full Text] [Related]

  • 2. Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells.
    Carter AA, Hill SJ.
    J Pharmacol Exp Ther; 2005 Nov; 315(2):839-48. PubMed ID: 16051698
    [Abstract] [Full Text] [Related]

  • 3. Salmeterol stimulation dissociates beta2-adrenergic receptor phosphorylation and internalization.
    Moore RH, Millman EE, Godines V, Hanania NA, Tran TM, Peng H, Dickey BF, Knoll BJ, Clark RB.
    Am J Respir Cell Mol Biol; 2007 Feb; 36(2):254-61. PubMed ID: 16980556
    [Abstract] [Full Text] [Related]

  • 4. Salmeterol-induced desensitization, internalization and phosphorylation of the human beta2-adrenoceptor.
    January B, Seibold A, Allal C, Whaley BS, Knoll BJ, Moore RH, Dickey BF, Barber R, Clark RB.
    Br J Pharmacol; 1998 Feb; 123(4):701-11. PubMed ID: 9517390
    [Abstract] [Full Text] [Related]

  • 5. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins.
    Perry SJ, Baillie GS, Kohout TA, McPhee I, Magiera MM, Ang KL, Miller WE, McLean AJ, Conti M, Houslay MD, Lefkowitz RJ.
    Science; 2002 Oct 25; 298(5594):834-6. PubMed ID: 12399592
    [Abstract] [Full Text] [Related]

  • 6. Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha).
    Finney PA, Donnelly LE, Belvisi MG, Chuang TT, Birrell M, Harris A, Mak JC, Scorer C, Barnes PJ, Adcock IM, Giembycz MA.
    Br J Pharmacol; 2001 Mar 25; 132(6):1261-70. PubMed ID: 11250877
    [Abstract] [Full Text] [Related]

  • 7. Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies.
    Tran TM, Friedman J, Qunaibi E, Baameur F, Moore RH, Clark RB.
    Mol Pharmacol; 2004 Jan 25; 65(1):196-206. PubMed ID: 14722251
    [Abstract] [Full Text] [Related]

  • 8. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.
    Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH.
    J Biol Chem; 2006 Mar 17; 281(11):7684-92. PubMed ID: 16407241
    [Abstract] [Full Text] [Related]

  • 9. Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK.
    Kobayashi H, Narita Y, Nishida M, Kurose H.
    Cell Signal; 2005 Oct 17; 17(10):1248-53. PubMed ID: 16038799
    [Abstract] [Full Text] [Related]

  • 10. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
    Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ.
    J Biol Chem; 2006 Jan 13; 281(2):1261-73. PubMed ID: 16280323
    [Abstract] [Full Text] [Related]

  • 11. Salmeterol, a long-acting beta 2-adrenoceptor agonist mediating cyclic AMP accumulation in a neuronal cell line.
    McCrea KE, Hill SJ.
    Br J Pharmacol; 1993 Oct 13; 110(2):619-26. PubMed ID: 7902176
    [Abstract] [Full Text] [Related]

  • 12. Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes.
    Shi Q, Li M, Mika D, Fu Q, Kim S, Phan J, Shen A, Vandecasteele G, Xiang YK.
    Cardiovasc Res; 2017 May 01; 113(6):656-670. PubMed ID: 28339772
    [Abstract] [Full Text] [Related]

  • 13. Influence of receptor density on the patterns of beta2-adrenocepter desensitization.
    Rousseau G, Guilbault N, Da Silva A, Mouillac B, Chidiac P, Bouvier M.
    Eur J Pharmacol; 1997 May 12; 326(1):75-84. PubMed ID: 9178658
    [Abstract] [Full Text] [Related]

  • 14. Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human beta2-adrenoceptor.
    McDonnell J, Latif ML, Rees ES, Bevan NJ, Hill SJ.
    Br J Pharmacol; 1998 Oct 12; 125(4):717-26. PubMed ID: 9831907
    [Abstract] [Full Text] [Related]

  • 15. Activation of a beta 2-adrenergic receptor/Gs alpha fusion protein elicits a desensitization-resistant cAMP signal capable of inhibiting proliferation of two cancer cell lines.
    Bertin B, Jockers R, Strosberg AD, Marullo S.
    Recept Channels; 1997 Oct 12; 5(1):41-51. PubMed ID: 9272575
    [Abstract] [Full Text] [Related]

  • 16. Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.
    Bolger GB, Baillie GS, Li X, Lynch MJ, Herzyk P, Mohamed A, Mitchell LH, McCahill A, Hundsrucker C, Klussmann E, Adams DR, Houslay MD.
    Biochem J; 2006 Aug 15; 398(1):23-36. PubMed ID: 16689683
    [Abstract] [Full Text] [Related]

  • 17. Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells.
    Pang L, Knox AJ.
    Am J Respir Cell Mol Biol; 2000 Jul 15; 23(1):79-85. PubMed ID: 10873156
    [Abstract] [Full Text] [Related]

  • 18. Development and characterization of pepducins as Gs-biased allosteric agonists.
    Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL.
    J Biol Chem; 2014 Dec 26; 289(52):35668-84. PubMed ID: 25395624
    [Abstract] [Full Text] [Related]

  • 19. Stable activation and desensitization of beta 2-adrenergic receptor stimulation of adenylyl cyclase by salmeterol: evidence for quasi-irreversible binding to an exosite.
    Clark RB, Allal C, Friedman J, Johnson M, Barber R.
    Mol Pharmacol; 1996 Jan 26; 49(1):182-9. PubMed ID: 8569705
    [Abstract] [Full Text] [Related]

  • 20. Kinetic analysis of drug-receptor interactions of long-acting beta2 sympathomimetics in isolated receptor membranes: evidence against prolonged effects of salmeterol and formoterol on receptor-coupled adenylyl cyclase.
    Teschemacher A, Lemoine H.
    J Pharmacol Exp Ther; 1999 Mar 26; 288(3):1084-92. PubMed ID: 10027845
    [Abstract] [Full Text] [Related]

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