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136 related items for PubMed ID: 25786874

  • 1. The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium.
    Fiorani M, Azzolini C, Cerioni L, Scotti M, Guidarelli A, Ciacci C, Cantoni O.
    Biochim Biophys Acta; 2015 Jun; 1848(6):1393-401. PubMed ID: 25786874
    [Abstract] [Full Text] [Related]

  • 2. Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2.
    Muñoz-Montesino C, Roa FJ, Peña E, González M, Sotomayor K, Inostroza E, Muñoz CA, González I, Maldonado M, Soliz C, Reyes AM, Vera JC, Rivas CI.
    Free Radic Biol Med; 2014 May; 70():241-54. PubMed ID: 24594434
    [Abstract] [Full Text] [Related]

  • 3. Sodium-dependent transport of ascorbic acid in U937 cell mitochondria.
    Azzolini C, Fiorani M, Cerioni L, Guidarelli A, Cantoni O.
    IUBMB Life; 2013 Feb; 65(2):149-53. PubMed ID: 23288661
    [Abstract] [Full Text] [Related]

  • 4. Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria.
    Fiorani M, Azzolini C, Guidarelli A, Cerioni L, Scotti M, Cantoni O.
    Pharmacol Res; 2015 Sep; 99():289-95. PubMed ID: 26188149
    [Abstract] [Full Text] [Related]

  • 5. Mechanistic insights and functional determinants of the transport cycle of the ascorbic acid transporter SVCT2. Activation by sodium and absolute dependence on bivalent cations.
    Godoy A, Ormazabal V, Moraga-Cid G, Zúñiga FA, Sotomayor P, Barra V, Vasquez O, Montecinos V, Mardones L, Guzmán C, Villagrán M, Aguayo LG, Oñate SA, Reyes AM, Cárcamo JG, Rivas CI, Vera JC.
    J Biol Chem; 2007 Jan 05; 282(1):615-24. PubMed ID: 17012227
    [Abstract] [Full Text] [Related]

  • 6. SVCT2-Dependent plasma and mitochondrial membrane transport of ascorbic acid in differentiating myoblasts.
    Fiorani M, Scotti M, Guidarelli A, Burattini S, Falcieri E, Cantoni O.
    Pharmacol Res; 2020 Sep 05; 159():105042. PubMed ID: 32580031
    [Abstract] [Full Text] [Related]

  • 7. Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid.
    Scotti M, Fiorani M, Guidarelli A, Cantoni O.
    Oxid Med Cell Longev; 2018 Sep 05; 2018():4194502. PubMed ID: 29576847
    [Abstract] [Full Text] [Related]

  • 8. Increased expression of mitochondrial sodium-coupled ascorbic acid transporter-2 (mitSVCT2) as a central feature in breast cancer.
    Peña E, Roa FJ, Inostroza E, Sotomayor K, González M, Gutierrez-Castro FA, Maurin M, Sweet K, Labrousse C, Gatica M, Aylwin CF, Mendoza P, Maldonado M, Delgado C, Madariaga J, Panes J, Silva-Grecchi T, Concha II, Moraga-Cid G, Reyes AM, Muñoz-Montesino C, Vera JC, Rivas CI.
    Free Radic Biol Med; 2019 May 01; 135():283-292. PubMed ID: 30902760
    [Abstract] [Full Text] [Related]

  • 9. Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells.
    Chothe PP, Chutkan N, Sangani R, Wenger KH, Prasad PD, Thangaraju M, Hamrick MW, Isales CM, Ganapathy V, Fulzele S.
    Spine J; 2013 May 01; 13(5):549-57. PubMed ID: 23415019
    [Abstract] [Full Text] [Related]

  • 10. Histidine residues in the Na+-coupled ascorbic acid transporter-2 (SVCT2) are central regulators of SVCT2 function, modulating pH sensitivity, transporter kinetics, Na+ cooperativity, conformational stability, and subcellular localization.
    Ormazabal V, Zuñiga FA, Escobar E, Aylwin C, Salas-Burgos A, Godoy A, Reyes AM, Vera JC, Rivas CI.
    J Biol Chem; 2010 Nov 19; 285(47):36471-85. PubMed ID: 20843809
    [Abstract] [Full Text] [Related]

  • 11. In silico aided thoughts on mitochondrial vitamin C transport.
    Szarka A, Balogh T.
    J Theor Biol; 2015 Jan 21; 365():181-9. PubMed ID: 25451960
    [Abstract] [Full Text] [Related]

  • 12. The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids.
    Caprile T, Salazar K, Astuya A, Cisternas P, Silva-Alvarez C, Montecinos H, Millán C, de Los Angeles García M, Nualart F.
    J Neurochem; 2009 Feb 21; 108(3):563-77. PubMed ID: 19054284
    [Abstract] [Full Text] [Related]

  • 13. Ascorbic acid transport in brain microvascular pericytes.
    Parker WH, Qu ZC, May JM.
    Biochem Biophys Res Commun; 2015 Mar 06; 458(2):262-7. PubMed ID: 25645015
    [Abstract] [Full Text] [Related]

  • 14. Functional and physiological role of vitamin C transporters.
    Bürzle M, Hediger MA.
    Curr Top Membr; 2012 Mar 06; 70():357-75. PubMed ID: 23177992
    [Abstract] [Full Text] [Related]

  • 15. Sodium-dependent vitamin C transporter-2 mediates vitamin C transport at the cortical nerve terminal.
    Pierce MR, Raj A, Betke KM, Zeidan LN, Matthies HJ, May JM.
    J Neurosci Res; 2015 Dec 06; 93(12):1881-90. PubMed ID: 26366722
    [Abstract] [Full Text] [Related]

  • 16. Mitochondrial Uptake and Accumulation of Vitamin C: What Can We Learn from Cell Culture Studies?
    Cantoni O, Guidarelli A, Fiorani M.
    Antioxid Redox Signal; 2018 Nov 20; 29(15):1502-1515. PubMed ID: 28699359
    [Abstract] [Full Text] [Related]

  • 17. Sodium-dependent ascorbic acid transporter family SLC23.
    Takanaga H, Mackenzie B, Hediger MA.
    Pflugers Arch; 2004 Feb 20; 447(5):677-82. PubMed ID: 12845532
    [Abstract] [Full Text] [Related]

  • 18. Human choroid plexus papilloma cells efficiently transport glucose and vitamin C.
    Ulloa V, García-Robles M, Martínez F, Salazar K, Reinicke K, Pérez F, Godoy DF, Godoy AS, Nualart F.
    J Neurochem; 2013 Nov 20; 127(3):403-14. PubMed ID: 23647458
    [Abstract] [Full Text] [Related]

  • 19. [Cellular and intracellular transport of vitamin C. The physiologic aspects].
    Szarka A, Lőrincz T.
    Orv Hetil; 2013 Oct 20; 154(42):1651-6. PubMed ID: 24121217
    [Abstract] [Full Text] [Related]

  • 20. Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells.
    Mardones L, Zúñiga FA, Villagrán M, Sotomayor K, Mendoza P, Escobar D, González M, Ormazabal V, Maldonado M, Oñate G, Angulo C, Concha II, Reyes AM, Cárcamo JG, Barra V, Vera JC, Rivas CI.
    Free Radic Biol Med; 2012 May 01; 52(9):1874-87. PubMed ID: 22348976
    [Abstract] [Full Text] [Related]

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