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5933 related items for PubMed ID: 25792811

  • 1. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 2. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 3. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():575-601. PubMed ID: 25632225
    [Abstract] [Full Text] [Related]

  • 4. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells.
    Ding YH, Zhou ZW, Ha CF, Zhang XY, Pan ST, He ZX, Edelman JL, Wang D, Yang YX, Zhang X, Duan W, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():425-64. PubMed ID: 25624750
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 6. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1293-318. PubMed ID: 25767376
    [Abstract] [Full Text] [Related]

  • 7. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 8. Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.
    Ren BJ, Zhou ZW, Zhu DJ, Ju YL, Wu JH, Ouyang MZ, Chen XW, Zhou SF.
    Int J Mol Sci; 2015 Dec 29; 17(1):. PubMed ID: 26729093
    [Abstract] [Full Text] [Related]

  • 9. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Zhou ZW, Pan ST, He ZX, Zhang X, Yang T, Pan SY, Duan W, He SM, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Dec 29; 9():1027-62. PubMed ID: 25733818
    [Abstract] [Full Text] [Related]

  • 10. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F, Wang Q, Zhou ZW, Yu SN, Pan ST, He ZX, Zhang X, Wang D, Yang YX, Yang T, Sun T, Li M, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Dec 29; 9():537-60. PubMed ID: 25632222
    [Abstract] [Full Text] [Related]

  • 11. Alisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cells.
    Liu Z, Wang F, Zhou ZW, Xia HC, Wang XY, Yang YX, He ZX, Sun T, Zhou SF.
    Am J Transl Res; 2017 Dec 29; 9(3):845-873. PubMed ID: 28386317
    [Abstract] [Full Text] [Related]

  • 12. Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.
    Zi D, Zhou ZW, Yang YJ, Huang L, Zhou ZL, He SM, He ZX, Zhou SF.
    Int J Mol Sci; 2015 Nov 13; 16(11):27228-51. PubMed ID: 26580601
    [Abstract] [Full Text] [Related]

  • 13. Alisertib induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells.
    Fu Y, Zhang Y, Gao M, Quan L, Gui R, Liu J.
    Mol Med Rep; 2016 Jul 13; 14(1):394-8. PubMed ID: 27177156
    [Abstract] [Full Text] [Related]

  • 14. Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.
    Zhou ZW, Li XX, He ZX, Pan ST, Yang Y, Zhang X, Chow K, Yang T, Qiu JX, Zhou Q, Tan J, Wang D, Zhou SF.
    Drug Des Devel Ther; 2015 Jul 13; 9():1511-54. PubMed ID: 25834399
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.
    Kim KY, Park KI, Kim SH, Yu SN, Park SG, Kim YW, Seo YK, Ma JY, Ahn SC.
    Int J Mol Sci; 2017 May 18; 18(5):. PubMed ID: 28524116
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of Aurora A Kinase by Alisertib Induces Autophagy and Cell Cycle Arrest and Increases Chemosensitivity in Human Hepatocellular Carcinoma HepG2 Cells.
    Zhu Q, Yu X, Zhou ZW, Zhou C, Chen XW, Zhou SF.
    Curr Cancer Drug Targets; 2017 May 18; 17(4):386-401. PubMed ID: 27396604
    [Abstract] [Full Text] [Related]

  • 17. Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with imatinib mesylate against chronic myelogenous leukemia cell lines.
    Xin P, Li C, Zheng Y, Peng Q, Xiao H, Huang Y, Zhu X.
    Drug Des Devel Ther; 2017 May 18; 11():1115-1126. PubMed ID: 28435223
    [Abstract] [Full Text] [Related]

  • 18. Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells.
    Kim SY, Hwangbo H, Kim MY, Ji SY, Lee H, Kim GY, Kwon CY, Leem SH, Hong SH, Cheong J, Choi YH.
    Arch Biochem Biophys; 2021 Jan 15; 697():108688. PubMed ID: 33227289
    [Abstract] [Full Text] [Related]

  • 19. Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
    Nagappan A, Lee WS, Yun JW, Lu JN, Chang SH, Jeong JH, Kim GS, Jung JM, Hong SC.
    PLoS One; 2017 Jan 15; 12(3):e0174591. PubMed ID: 28355296
    [Abstract] [Full Text] [Related]

  • 20. Luteoloside induces G0/G1 arrest and pro-death autophagy through the ROS-mediated AKT/mTOR/p70S6K signalling pathway in human non-small cell lung cancer cell lines.
    Zhou M, Shen S, Zhao X, Gong X.
    Biochem Biophys Res Commun; 2017 Dec 09; 494(1-2):263-269. PubMed ID: 29024631
    [Abstract] [Full Text] [Related]

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