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Journal Abstract Search

119 related items for PubMed ID: 2579548

  • 1. Tetrahydrouridine, cytidine analogues, and hemoglobin F.
    DeSimone J, Heller P, Molokie RE, Hall L, Zwiers D.
    Am J Hematol; 1985 Mar; 18(3):283-8. PubMed ID: 2579548
    [Abstract] [Full Text] [Related]

  • 2. Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.
    Molokie R, Lavelle D, Gowhari M, Pacini M, Krauz L, Hassan J, Ibanez V, Ruiz MA, Ng KP, Woost P, Radivoyevitch T, Pacelli D, Fada S, Rump M, Hsieh M, Tisdale JF, Jacobberger J, Phelps M, Engel JD, Saraf S, Hsu LL, Gordeuk V, DeSimone J, Saunthararajah Y.
    PLoS Med; 2017 Sep; 14(9):e1002382. PubMed ID: 28880867
    [Abstract] [Full Text] [Related]

  • 3. On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation.
    Lavelle D, DeSimone J, Heller P, Zwiers D, Hall L.
    Blood; 1986 Apr; 67(4):1083-9. PubMed ID: 2420395
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase.
    Ferraris D, Duvall B, Delahanty G, Mistry B, Alt J, Rojas C, Rowbottom C, Sanders K, Schuck E, Huang KC, Redkar S, Slusher BB, Tsukamoto T.
    J Med Chem; 2014 Mar 27; 57(6):2582-8. PubMed ID: 24520856
    [Abstract] [Full Text] [Related]

  • 5. Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.
    Lavelle D, Vaitkus K, Ling Y, Ruiz MA, Mahfouz R, Ng KP, Negrotto S, Smith N, Terse P, Engelke KJ, Covey J, Chan KK, Desimone J, Saunthararajah Y.
    Blood; 2012 Feb 02; 119(5):1240-7. PubMed ID: 22160381
    [Abstract] [Full Text] [Related]

  • 6. On the interaction of 3,4,5,6-tetrahydrouridine with human liver cytidine deaminase.
    Wentworth DF, Wolfenden R.
    Biochemistry; 1975 Nov 18; 14(23):5099-105. PubMed ID: 53069
    [Abstract] [Full Text] [Related]

  • 7. Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase.
    Laliberté J, Marquez VE, Momparler RL.
    Cancer Chemother Pharmacol; 1992 Nov 18; 30(1):7-11. PubMed ID: 1375134
    [Abstract] [Full Text] [Related]

  • 8. Fetal hemoglobin production in adult baboons by 5-azacytidine or by phenylhydrazine-induced hemolysis is associated with hypomethylation of globin gene DNA.
    DeSimone J, Heller P, Schimenti JC, Duncan CH.
    Prog Clin Biol Res; 1983 Nov 18; 134():489-500. PubMed ID: 6198662
    [Abstract] [Full Text] [Related]

  • 9. 5-Azacytidine and fetal hemoglobin.
    Heller P, DeSimone J.
    Am J Hematol; 1984 Nov 18; 17(4):439-47. PubMed ID: 6208778
    [Abstract] [Full Text] [Related]

  • 10. On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC.
    Constantoulakis P, Knitter G, Stamatoyannopoulos G.
    Blood; 1989 Nov 01; 74(6):1963-71. PubMed ID: 2478217
    [Abstract] [Full Text] [Related]

  • 11. Promoter sequence differences may determine maximal hemoglobin F levels in 5-azacytidine treated baboons.
    Lavelle DE, DeSimone J.
    Prog Clin Biol Res; 1989 Nov 01; 316A():261-8. PubMed ID: 2480610
    [No Abstract] [Full Text] [Related]

  • 12. 5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.
    DeSimone J, Heller P, Hall L, Zwiers D.
    Proc Natl Acad Sci U S A; 1982 Jul 01; 79(14):4428-31. PubMed ID: 6181507
    [Abstract] [Full Text] [Related]

  • 13. Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice.
    Beumer JH, Eiseman JL, Parise RA, Florian JA, Joseph E, D'Argenio DZ, Parker RS, Kay B, Covey JM, Egorin MJ.
    Cancer Chemother Pharmacol; 2008 Aug 01; 62(3):457-64. PubMed ID: 18008070
    [Abstract] [Full Text] [Related]

  • 14. Subchronic oral toxicity study of decitabine in combination with tetrahydrouridine in CD-1 mice.
    Terse P, Engelke K, Chan K, Ling Y, Sharpnack D, Saunthararajah Y, Covey JM.
    Int J Toxicol; 2014 Aug 01; 33(2):75-85. PubMed ID: 24639139
    [Abstract] [Full Text] [Related]

  • 15. Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
    Voytek P, Beisler JA, Abbasi MM, Wolpert-DeFilippes MK.
    Cancer Res; 1977 Jul 01; 37(7 Pt 1):1956-61. PubMed ID: 67884
    [Abstract] [Full Text] [Related]

  • 16. Influence of tetrahydrouridine on the pharmacokinetics of intrathecally administered 1-beta-D-arabinofuranosylcytosine.
    Riccardi R, Chabner B, Glaubiger DL, Wood J, Poplack DG.
    Cancer Res; 1982 May 01; 42(5):1736-9. PubMed ID: 6896013
    [Abstract] [Full Text] [Related]

  • 17. Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
    Kreis W, Hession C, Soricelli A, Scully K.
    Cancer Treat Rep; 1977 Oct 01; 61(7):1355-64. PubMed ID: 589601
    [Abstract] [Full Text] [Related]

  • 18. Epimer interconversion, isomerization, and hydrolysis of tetrahydrouridine: implications for cytidine deaminase inhibition.
    Xiang TX, Niemi R, Bummer P, Anderson BD.
    J Pharm Sci; 2003 Oct 01; 92(10):2027-39. PubMed ID: 14502542
    [Abstract] [Full Text] [Related]

  • 19. Induction of hemoglobin F synthesis in patients with beta thalassemia.
    Ley TJ, Nienhuis AW.
    Annu Rev Med; 1985 Oct 01; 36():485-98. PubMed ID: 2581500
    [Abstract] [Full Text] [Related]

  • 20. Combined inhibition of histone deacetylase and cytidine deaminase improves epigenetic potency of decitabine in colorectal adenocarcinomas.
    Tang Z, Liu L, Borlak J.
    Clin Epigenetics; 2023 May 19; 15(1):89. PubMed ID: 37208732
    [Abstract] [Full Text] [Related]

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