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Journal Abstract Search

365 related items for PubMed ID: 25803559

  • 1.
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  • 2. Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactions.
    Boelsterli UA.
    Curr Drug Metab; 2002 Aug; 3(4):439-50. PubMed ID: 12093359
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  • 5. Acyl glucuronide metabolites: Implications for drug safety assessment.
    Van Vleet TR, Liu H, Lee A, Blomme EAG.
    Toxicol Lett; 2017 Apr 15; 272():1-7. PubMed ID: 28286018
    [Abstract] [Full Text] [Related]

  • 6. Bioactivation of GPR40 Agonist MK-8666: Formation of Protein Adducts in Vitro from Reactive Acyl Glucuronide and Acyl CoA Thioester.
    Shang J, Tschirret-Guth R, Cancilla M, Samuel K, Chen Q, Chobanian HR, Thomas A, Tong W, Josien H, Buevich AV, Mitra K.
    Chem Res Toxicol; 2020 Jan 21; 33(1):191-201. PubMed ID: 31566356
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  • 7. Safety Assessment of Acyl Glucuronides-A Simplified Paradigm.
    Smith DA, Hammond T, Baillie TA.
    Drug Metab Dispos; 2018 Jun 21; 46(6):908-912. PubMed ID: 29559442
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  • 8. Toxicity of Carboxylic Acid-Containing Drugs: The Role of Acyl Migration and CoA Conjugation Investigated.
    Lassila T, Hokkanen J, Aatsinki SM, Mattila S, Turpeinen M, Tolonen A.
    Chem Res Toxicol; 2015 Dec 21; 28(12):2292-303. PubMed ID: 26558897
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  • 9. Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme A thioester intermediate in rats.
    Olsen J, Li C, Skonberg C, Bjørnsdottir I, Sidenius U, Benet LZ, Hansen SH.
    Drug Metab Dispos; 2007 May 21; 35(5):758-64. PubMed ID: 17303625
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  • 10. Acyl glucuronides: the good, the bad and the ugly.
    Regan SL, Maggs JL, Hammond TG, Lambert C, Williams DP, Park BK.
    Biopharm Drug Dispos; 2010 Oct 21; 31(7):367-95. PubMed ID: 20830700
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  • 11. Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.
    Li C, Benet LZ, Grillo MP.
    Chem Res Toxicol; 2002 Oct 21; 15(10):1309-17. PubMed ID: 12387630
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  • 12. Acyl glucuronide reactivity in perspective: biological consequences.
    Bailey MJ, Dickinson RG.
    Chem Biol Interact; 2003 May 06; 145(2):117-37. PubMed ID: 12686489
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  • 13. Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin.
    Bolze S, Bromet N, Gay-Feutry C, Massiere F, Boulieu R, Hulot T.
    Drug Metab Dispos; 2002 Apr 06; 30(4):404-13. PubMed ID: 11901094
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  • 14. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ, Dickinson RG.
    Chem Res Toxicol; 1996 Apr 06; 9(3):659-66. PubMed ID: 8728513
    [Abstract] [Full Text] [Related]

  • 15. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides.
    Zhong S, Jones R, Lu W, Schadt S, Ottaviani G.
    Drug Metab Dispos; 2015 Nov 06; 43(11):1711-7. PubMed ID: 26276581
    [Abstract] [Full Text] [Related]

  • 16. In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid.
    Rodrigues AV, Rollison HE, Martin S, Sarda S, Schulz-Utermoehl T, Stahl S, Gustafsson F, Eakins J, Kenna JG, Wilson ID.
    Arch Toxicol; 2013 Aug 06; 87(8):1569-79. PubMed ID: 23609606
    [Abstract] [Full Text] [Related]

  • 17. Species differences in the elimination of a peroxisome proliferator-activated receptor agonist highlighted by oxidative metabolism of its acyl glucuronide.
    Kochansky CJ, Xia YQ, Wang S, Cato B, Creighton M, Vincent SH, Franklin RB, Reed JR.
    Drug Metab Dispos; 2005 Dec 06; 33(12):1894-904. PubMed ID: 16183782
    [Abstract] [Full Text] [Related]

  • 18. Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Walker GS, Atherton J, Bauman J, Kohl C, Lam W, Reily M, Lou Z, Mutlib A.
    Chem Res Toxicol; 2007 Jun 06; 20(6):876-86. PubMed ID: 17536843
    [Abstract] [Full Text] [Related]

  • 19. Drug-S-acyl-glutathione thioesters: synthesis, bioanalytical properties, chemical reactivity, biological formation and degradation.
    Grillo MP.
    Curr Drug Metab; 2011 Mar 06; 12(3):229-44. PubMed ID: 20946099
    [Abstract] [Full Text] [Related]

  • 20. Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites.
    Olsen J, Bjørnsdottir I, Honorè Hansen S.
    Xenobiotica; 2003 May 06; 33(5):561-70. PubMed ID: 12746110
    [Abstract] [Full Text] [Related]

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