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128 related items for PubMed ID: 25809564

  • 1. U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin.
    Guidarelli A, Fiorani M, Azzolini C, Cerioni L, Scotti M, Cantoni O.
    Biofactors; 2015; 41(2):101-10. PubMed ID: 25809564
    [Abstract] [Full Text] [Related]

  • 2. Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite.
    Guidarelli A, Cerioni L, Fiorani M, Azzolini C, Cantoni O.
    Biofactors; 2014; 40(2):236-46. PubMed ID: 24105898
    [Abstract] [Full Text] [Related]

  • 3. Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria.
    Fiorani M, Azzolini C, Guidarelli A, Cerioni L, Scotti M, Cantoni O.
    Pharmacol Res; 2015 Sep; 99():289-95. PubMed ID: 26188149
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial ascorbic acid prevents mitochondrial O₂·⁻ formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms.
    Guidarelli A, Carloni S, Balduini W, Fiorani M, Cantoni O.
    Biofactors; 2016 Sep; 42(2):190-200. PubMed ID: 26893200
    [Abstract] [Full Text] [Related]

  • 5. Enhancing effects of intracellular ascorbic acid on peroxynitrite-induced U937 cell death are mediated by mitochondrial events resulting in enhanced sensitivity to peroxynitrite-dependent inhibition of complex III and formation of hydrogen peroxide.
    Guidarelli A, Fiorani M, Cantoni O.
    Biochem J; 2004 Mar 15; 378(Pt 3):959-66. PubMed ID: 14627438
    [Abstract] [Full Text] [Related]

  • 6. Pterostilbene induces mitochondrially derived apoptosis in breast cancer cells in vitro.
    Moon D, McCormack D, McDonald D, McFadden D.
    J Surg Res; 2013 Apr 15; 180(2):208-15. PubMed ID: 22572619
    [Abstract] [Full Text] [Related]

  • 7. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 8. Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells.
    Azzolini C, Fiorani M, Guidarelli A, Cantoni O.
    Br J Nutr; 2012 Mar 22; 107(5):691-6. PubMed ID: 21794197
    [Abstract] [Full Text] [Related]

  • 9. Ascorbic acid, but not dehydroascorbic acid increases intracellular vitamin C content to decrease Hypoxia Inducible Factor -1 alpha activity and reduce malignant potential in human melanoma.
    Fischer AP, Miles SL.
    Biomed Pharmacother; 2017 Feb 22; 86():502-513. PubMed ID: 28012930
    [Abstract] [Full Text] [Related]

  • 10. The compartmentalised nature of the mechanisms governing superoxide formation and scavenging in cells exposed to arsenite.
    Guidarelli A, Fiorani M, Cerioni L, Cantoni O.
    Toxicol Appl Pharmacol; 2019 Dec 01; 384():114766. PubMed ID: 31647942
    [Abstract] [Full Text] [Related]

  • 11. Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling.
    Guidarelli A, Fiorani M, Cerioni L, Cantoni O.
    Redox Biol; 2019 Jan 01; 20():285-295. PubMed ID: 30388683
    [Abstract] [Full Text] [Related]

  • 12. Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury.
    KC S, Cárcamo JM, Golde DW.
    FASEB J; 2005 Oct 01; 19(12):1657-67. PubMed ID: 16195374
    [Abstract] [Full Text] [Related]

  • 13. A novel biological role of dehydroascorbic acid: Inhibition of Na(+)-dependent transport of ascorbic acid.
    Fiorani M, Azzolini C, Guidarelli A, Cerioni L, Cantoni O.
    Pharmacol Res; 2014 Jun 01; 84():12-7. PubMed ID: 24769194
    [Abstract] [Full Text] [Related]

  • 14. Vitamin E protects against the mitochondrial damage caused by cyclosporin A in LLC-PK1 cells.
    de Arriba G, de Hornedo JP, Rubio SR, Fernández MC, Martínez SB, Camarero MM, Cid TP.
    Toxicol Appl Pharmacol; 2009 Sep 15; 239(3):241-50. PubMed ID: 19523970
    [Abstract] [Full Text] [Related]

  • 15. Smac/DIABLO and cytochrome c are released from mitochondria through a similar mechanism during UV-induced apoptosis.
    Zhou LL, Zhou LY, Luo KQ, Chang DC.
    Apoptosis; 2005 Mar 15; 10(2):289-99. PubMed ID: 15843890
    [Abstract] [Full Text] [Related]

  • 16. Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide.
    Bartling B, Lewensohn R, Zhivotovsky B.
    Exp Cell Res; 2004 Aug 01; 298(1):83-95. PubMed ID: 15242764
    [Abstract] [Full Text] [Related]

  • 17. High fluence low-power laser irradiation induces mitochondrial permeability transition mediated by reactive oxygen species.
    Wu S, Xing D, Gao X, Chen WR.
    J Cell Physiol; 2009 Mar 01; 218(3):603-11. PubMed ID: 19006121
    [Abstract] [Full Text] [Related]

  • 18. Hypoxia-reoxygenation-induced mitochondrial damage and apoptosis in human endothelial cells are inhibited by vitamin C.
    Dhar-Mascareño M, Cárcamo JM, Golde DW.
    Free Radic Biol Med; 2005 May 15; 38(10):1311-22. PubMed ID: 15855049
    [Abstract] [Full Text] [Related]

  • 19. Sodium-dependent transport of ascorbic acid in U937 cell mitochondria.
    Azzolini C, Fiorani M, Cerioni L, Guidarelli A, Cantoni O.
    IUBMB Life; 2013 Feb 15; 65(2):149-53. PubMed ID: 23288661
    [Abstract] [Full Text] [Related]

  • 20. The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection.
    Fiorani M, Guidarelli A, Capellacci V, Cerioni L, Crinelli R, Cantoni O.
    Toxicol Appl Pharmacol; 2018 Apr 15; 345():26-35. PubMed ID: 29526526
    [Abstract] [Full Text] [Related]

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