These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53. Yang MC, Lin RW, Huang SB, Huang SY, Chen WJ, Wang S, Hong YR, Wang C. Cell Cycle; 2016; 15(3):394-402. PubMed ID: 26694174 [Abstract] [Full Text] [Related]
3. Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition. Tamaki H, Harashima N, Hiraki M, Arichi N, Nishimura N, Shiina H, Naora K, Harada M. Oncotarget; 2014 Nov 30; 5(22):11399-412. PubMed ID: 25333266 [Abstract] [Full Text] [Related]
4. Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Shi J, Zhou Y, Huang HC, Mitchison TJ. Cancer Res; 2011 Jul 01; 71(13):4518-26. PubMed ID: 21546570 [Abstract] [Full Text] [Related]
5. Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells. Okamoto K, Zaanan A, Kawakami H, Huang S, Sinicrope FA. Mol Cancer Res; 2015 Apr 01; 13(4):659-69. PubMed ID: 25548100 [Abstract] [Full Text] [Related]
6. A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells. Yamanaka K, Rocchi P, Miyake H, Fazli L, Vessella B, Zangemeister-Wittke U, Gleave ME. Mol Cancer Ther; 2005 Nov 01; 4(11):1689-98. PubMed ID: 16275990 [Abstract] [Full Text] [Related]
7. Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells. Li X, Li B, Ni Z, Zhou P, Wang B, He J, Xiong H, Yang F, Wu Y, Lyu X, Zhang Y, Zeng Y, Lian J, He F. Mol Cancer Ther; 2017 Sep 01; 16(9):1806-1818. PubMed ID: 28533436 [Abstract] [Full Text] [Related]
10. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N. Biochem Biophys Res Commun; 2016 Apr 29; 473(2):490-6. PubMed ID: 26996126 [Abstract] [Full Text] [Related]
11. Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. Inoue-Yamauchi A, Jeng PS, Kim K, Chen HC, Han S, Ganesan YT, Ishizawa K, Jebiwott S, Dong Y, Pietanza MC, Hellmann MD, Kris MG, Hsieh JJ, Cheng EH. Nat Commun; 2017 Jul 17; 8():16078. PubMed ID: 28714472 [Abstract] [Full Text] [Related]
15. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib. Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N. Hepatology; 2010 Oct 17; 52(4):1310-21. PubMed ID: 20799354 [Abstract] [Full Text] [Related]
16. Apigenin sensitizes colon cancer cells to antitumor activity of ABT-263. Shao H, Jing K, Mahmoud E, Huang H, Fang X, Yu C. Mol Cancer Ther; 2013 Dec 17; 12(12):2640-50. PubMed ID: 24126433 [Abstract] [Full Text] [Related]
17. Down-modulation of Bcl-2 sensitizes PTEN-mutated prostate cancer cells to starvation and taxanes. Calastretti A, Gatti G, Quaresmini C, Bevilacqua A. Prostate; 2014 Oct 17; 74(14):1411-22. PubMed ID: 25111376 [Abstract] [Full Text] [Related]
18. Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel. Wang Z, Goulet R, Stanton KJ, Sadaria M, Nakshatri H. Anticancer Res; 2005 Oct 17; 25(3c):2367-79. PubMed ID: 16080463 [Abstract] [Full Text] [Related]
19. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, Taub JW, Lin H, Ge Y. Oncotarget; 2016 Jun 07; 7(23):34785-99. PubMed ID: 27166183 [Abstract] [Full Text] [Related]