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Journal Abstract Search

377 related items for PubMed ID: 25825738

  • 1. Autoinhibition of MDMX by intramolecular p53 mimicry.
    Chen L, Borcherds W, Wu S, Becker A, Schonbrunn E, Daughdrill GW, Chen J.
    Proc Natl Acad Sci U S A; 2015 Apr 14; 112(15):4624-9. PubMed ID: 25825738
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  • 4. Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX.
    Borcherds W, Becker A, Chen L, Chen J, Chemes LB, Daughdrill GW.
    Biophys J; 2017 May 23; 112(10):2038-2042. PubMed ID: 28487147
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  • 5. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors.
    Chen R, Zhou J, Qin L, Chen Y, Huang Y, Liu H, Su Z.
    Biochemistry; 2017 Jun 27; 56(25):3273-3282. PubMed ID: 28581721
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  • 6. Molecular basis for the inhibition of p53 by Mdmx.
    Popowicz GM, Czarna A, Rothweiler U, Szwagierczak A, Krajewski M, Weber L, Holak TA.
    Cell Cycle; 2007 Oct 01; 6(19):2386-92. PubMed ID: 17938582
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  • 7. Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.
    Zdzalik M, Pustelny K, Kedracka-Krok S, Huben K, Pecak A, Wladyka B, Jankowski S, Dubin A, Potempa J, Dubin G.
    Cell Cycle; 2010 Nov 15; 9(22):4584-91. PubMed ID: 21088494
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  • 8. Competitive binding between dynamic p53 transactivation subdomains to human MDM2 protein: implications for regulating the p53·MDM2/MDMX interaction.
    Shan B, Li DW, Brüschweiler-Li L, Brüschweiler R.
    J Biol Chem; 2012 Aug 31; 287(36):30376-84. PubMed ID: 22807444
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  • 9. Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding.
    Wu S, Chen L, Becker A, Schonbrunn E, Chen J.
    Mol Cell Biol; 2012 Dec 31; 32(23):4821-32. PubMed ID: 23028042
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  • 10. Computational studies of difference in binding modes of peptide and non-peptide inhibitors to MDM2/MDMX based on molecular dynamics simulations.
    Chen J, Zhang D, Zhang Y, Li G.
    Int J Mol Sci; 2012 Dec 31; 13(2):2176-2195. PubMed ID: 22408446
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  • 11. The MDMX acidic domain competes with the p53 transactivation domain for MDM2 N-terminal domain binding.
    Song Q, Liu XQ, Rainey JK.
    Biochim Biophys Acta Mol Cell Res; 2022 Oct 31; 1869(10):119319. PubMed ID: 35780910
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  • 12. The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization.
    Leslie PL, Ke H, Zhang Y.
    J Biol Chem; 2015 May 15; 290(20):12941-50. PubMed ID: 25809483
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  • 13. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
    Shin JS, Ha JH, Chi SW.
    Biochem Biophys Res Commun; 2014 Jan 17; 443(3):882-7. PubMed ID: 24342622
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  • 14. On the interaction mechanisms of a p53 peptide and nutlin with the MDM2 and MDMX proteins: a Brownian dynamics study.
    ElSawy KM, Verma CS, Joseph TL, Lane DP, Twarock R, Caves LS.
    Cell Cycle; 2013 Feb 01; 12(3):394-404. PubMed ID: 23324352
    [Abstract] [Full Text] [Related]

  • 15. Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.
    Li C, Pazgier M, Li C, Yuan W, Liu M, Wei G, Lu WY, Lu W.
    J Mol Biol; 2010 Apr 30; 398(2):200-13. PubMed ID: 20226197
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  • 16. Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding.
    Wei X, Wu S, Song T, Chen L, Gao M, Borcherds W, Daughdrill GW, Chen J.
    Proc Natl Acad Sci U S A; 2016 May 10; 113(19):E2558-63. PubMed ID: 27114532
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  • 17. Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
    Popowicz GM, Czarna A, Holak TA.
    Cell Cycle; 2008 Aug 10; 7(15):2441-3. PubMed ID: 18677113
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  • 18. MDMX: a novel p53-binding protein with some functional properties of MDM2.
    Shvarts A, Steegenga WT, Riteco N, van Laar T, Dekker P, Bazuine M, van Ham RC, van der Houven van Oordt W, Hateboer G, van der Eb AJ, Jochemsen AG.
    EMBO J; 1996 Oct 01; 15(19):5349-57. PubMed ID: 8895579
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  • 19. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
    Okamoto K, Taya Y, Nakagama H.
    FEBS Lett; 2009 Sep 03; 583(17):2710-4. PubMed ID: 19619542
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  • 20. Comparative study of the p53-mdm2 and p53-MDMX interfaces.
    Böttger V, Böttger A, Garcia-Echeverria C, Ramos YF, van der Eb AJ, Jochemsen AG, Lane DP.
    Oncogene; 1999 Jan 07; 18(1):189-99. PubMed ID: 9926934
    [Abstract] [Full Text] [Related]

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