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Journal Abstract Search

454 related items for PubMed ID: 25829540

  • 1. Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.
    Pereira L, Rehmann H, Lao DH, Erickson JR, Bossuyt J, Chen J, Bers DM.
    Proc Natl Acad Sci U S A; 2015 Mar 31; 112(13):3991-6. PubMed ID: 25829540
    [Abstract] [Full Text] [Related]

  • 2. EPAC1 and 2 inhibit K+ currents via PLC/PKC and NOS/PKG pathways in rat ventricular cardiomyocytes.
    Boileve A, Romito O, Hof T, Levallois A, Brard L, d'Hers S, Fouchet A, Simard C, Guinamard R, Brette F, Sallé L.
    Am J Physiol Cell Physiol; 2024 Sep 01; 327(3):C557-C570. PubMed ID: 38985989
    [Abstract] [Full Text] [Related]

  • 3. Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.
    Pereira L, Cheng H, Lao DH, Na L, van Oort RJ, Brown JH, Wehrens XH, Chen J, Bers DM.
    Circulation; 2013 Feb 26; 127(8):913-22. PubMed ID: 23363625
    [Abstract] [Full Text] [Related]

  • 4. β-Adrenergic induced SR Ca2+ leak is mediated by an Epac-NOS pathway.
    Pereira L, Bare DJ, Galice S, Shannon TR, Bers DM.
    J Mol Cell Cardiol; 2017 Jul 26; 108():8-16. PubMed ID: 28476660
    [Abstract] [Full Text] [Related]

  • 5. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.
    Roscioni SS, Kistemaker LE, Menzen MH, Elzinga CR, Gosens R, Halayko AJ, Meurs H, Schmidt M.
    Respir Res; 2009 Sep 29; 10(1):88. PubMed ID: 19788733
    [Abstract] [Full Text] [Related]

  • 6. Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A.
    Yokoyama U, Minamisawa S, Quan H, Akaike T, Suzuki S, Jin M, Jiao Q, Watanabe M, Otsu K, Iwasaki S, Nishimaki S, Sato M, Ishikawa Y.
    J Biol Chem; 2008 Oct 17; 283(42):28702-9. PubMed ID: 18697745
    [Abstract] [Full Text] [Related]

  • 7. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
    Courilleau D, Bouyssou P, Fischmeister R, Lezoualc'h F, Blondeau JP.
    Biochem Biophys Res Commun; 2013 Oct 25; 440(3):443-8. PubMed ID: 24099776
    [Abstract] [Full Text] [Related]

  • 8. The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes.
    Pereira L, Métrich M, Fernández-Velasco M, Lucas A, Leroy J, Perrier R, Morel E, Fischmeister R, Richard S, Bénitah JP, Lezoualc'h F, Gómez AM.
    J Physiol; 2007 Sep 01; 583(Pt 2):685-94. PubMed ID: 17599964
    [Abstract] [Full Text] [Related]

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  • 10. CD44 regulates Epac1-mediated β-adrenergic-receptor-induced Ca2+-handling abnormalities: implication in cardiac arrhythmias.
    Chan YH, Tsai FC, Chang GJ, Lai YJ, Chang SH, Chen WJ, Yeh YH.
    J Biomed Sci; 2023 Jul 14; 30(1):55. PubMed ID: 37452346
    [Abstract] [Full Text] [Related]

  • 11. Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress.
    Laudette M, Coluccia A, Sainte-Marie Y, Solari A, Fazal L, Sicard P, Silvestri R, Mialet-Perez J, Pons S, Ghaleh B, Blondeau JP, Lezoualc'h F.
    Cardiovasc Res; 2019 Oct 01; 115(12):1766-1777. PubMed ID: 30873562
    [Abstract] [Full Text] [Related]

  • 12. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L, Nygaard G, Kopperud R, Krakstad C, Døskeland SO, Selheim F.
    Biochem Biophys Res Commun; 2013 Aug 09; 437(4):603-8. PubMed ID: 23850619
    [Abstract] [Full Text] [Related]

  • 13. Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.
    Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita K, Kawakami Y, Hamaguchi S, Abe T, Kiyonari H, Tsunematsu T, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, Ishikawa Y.
    J Clin Invest; 2014 Jun 09; 124(6):2785-801. PubMed ID: 24892712
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  • 15. Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy.
    Laurent AC, Bisserier M, Lucas A, Tortosa F, Roumieux M, De Régibus A, Swiader A, Sainte-Marie Y, Heymes C, Vindis C, Lezoualc'h F.
    Cardiovasc Res; 2015 Jan 01; 105(1):55-64. PubMed ID: 25411381
    [Abstract] [Full Text] [Related]

  • 16. The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
    Misra UK, Kaczowka S, Pizzo SV.
    Cell Signal; 2008 Aug 01; 20(8):1459-70. PubMed ID: 18495429
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  • 18. Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes.
    Lezcano N, Mariángelo JIE, Vittone L, Wehrens XHT, Said M, Mundiña-Weilenmann C.
    J Mol Cell Cardiol; 2018 Jan 01; 114():1-9. PubMed ID: 29037982
    [Abstract] [Full Text] [Related]

  • 19. EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.
    Yang Y, Yang F, Wu X, Lv X, Li J.
    Can J Physiol Pharmacol; 2016 May 01; 94(5):498-507. PubMed ID: 26854595
    [Abstract] [Full Text] [Related]

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