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Journal Abstract Search

197 related items for PubMed ID: 25845909

  • 1. Universality of Oxime K203 for Reactivation of Nerve Agent-Inhibited AChE.
    Kuca K, Hrabinova M, Jun D, Musilek K, Penhaker M, Krejcar O, Soukup O.
    Med Chem; 2015; 11(7):683-6. PubMed ID: 25845909
    [Abstract] [Full Text] [Related]

  • 2. A comparison of the ability of a new bispyridinium oxime--1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Kassa J.
    J Enzyme Inhib Med Chem; 2003 Dec; 18(6):529-35. PubMed ID: 15008517
    [Abstract] [Full Text] [Related]

  • 3. Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.
    Kuca K, Musilek K, Jun D, Pohanka M, Ghosh KK, Hrabinova M.
    J Enzyme Inhib Med Chem; 2010 Aug; 25(4):509-12. PubMed ID: 20192902
    [Abstract] [Full Text] [Related]

  • 4. A comparison of the efficacy of a bispyridinium oxime--1,4-bis-(2-hydroxyiminomethylpyridinium) butane dibromide and currently used oximes to reactivate sarin, tabun or cyclosarin-inhibited acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J.
    Pharmazie; 2004 Oct; 59(10):795-8. PubMed ID: 15544060
    [Abstract] [Full Text] [Related]

  • 5. A comparison of the potency of the oxime HLö-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods.
    Kuca K, Cabal J, Kassa J, Jun D, Hrabinová M.
    Acta Medica (Hradec Kralove); 2005 Oct; 48(2):81-6. PubMed ID: 16259317
    [Abstract] [Full Text] [Related]

  • 6. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity.
    Calić M, Vrdoljak AL, Radić B, Jelić D, Jun D, Kuca K, Kovarik Z.
    Toxicology; 2006 Feb 15; 219(1-3):85-96. PubMed ID: 16332406
    [Abstract] [Full Text] [Related]

  • 7. Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics.
    Worek F, Koller M, Thiermann H, Wille T.
    Toxicology; 2016 Mar 28; 350-352():25-30. PubMed ID: 27153754
    [Abstract] [Full Text] [Related]

  • 8. Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents.
    Zorbaz T, Malinak D, Maraković N, Maček Hrvat N, Zandona A, Novotny M, Skarka A, Andrys R, Benkova M, Soukup O, Katalinić M, Kuca K, Kovarik Z, Musilek K.
    J Med Chem; 2018 Dec 13; 61(23):10753-10766. PubMed ID: 30383374
    [Abstract] [Full Text] [Related]

  • 9. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J, Karasova J, Musilek K, Kuca K.
    Toxicology; 2008 Jan 20; 243(3):311-6. PubMed ID: 18054821
    [Abstract] [Full Text] [Related]

  • 10. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM, Brecht KM, Sweeney RE.
    Chem Biol Interact; 2013 Mar 25; 203(1):72-6. PubMed ID: 22982773
    [Abstract] [Full Text] [Related]

  • 11. Reactivation of organophosphate-inhibited acetylcholinesterase by quaternary pyridinium aldoximes.
    Kuca K, Patocka J, Cabal J, Jun D.
    Neurotox Res; 2004 Mar 25; 6(7-8):565-70. PubMed ID: 15639788
    [Abstract] [Full Text] [Related]

  • 12. Potency of new structurally different oximes to reactivate cyclosarin-inhibited human brain acetylcholinesterases.
    Kuca K, Cabal J, Jun D, Bajgar J, Hrabinova M.
    J Enzyme Inhib Med Chem; 2006 Dec 25; 21(6):663-6. PubMed ID: 17252938
    [Abstract] [Full Text] [Related]

  • 13. Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes.
    Kuca K, Jun D.
    J Med Toxicol; 2006 Dec 25; 2(4):141-6. PubMed ID: 18072133
    [Abstract] [Full Text] [Related]

  • 14. A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice.
    Kassa J, Karasova JZ, Caisberger F, Musilek K, Kuca K, Jung YS.
    J Enzyme Inhib Med Chem; 2010 Aug 25; 25(4):480-4. PubMed ID: 20233085
    [Abstract] [Full Text] [Related]

  • 15. In vitro reactivation potency of acetylcholinesterase reactivators--K074 and K075--to reactivate tabun-inhibited human brain cholinesterases.
    Kuca K, Cabal J, Jun D, Musilek K.
    Neurotox Res; 2007 Feb 25; 11(2):101-6. PubMed ID: 17449453
    [Abstract] [Full Text] [Related]

  • 16. Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase.
    Sahu AK, Sharma R, Gupta B, Musilek K, Kuca K, Acharya J, Ghosh KK.
    Toxicol Mech Methods; 2016 Jun 25; 26(5):319-26. PubMed ID: 27101948
    [Abstract] [Full Text] [Related]

  • 17. Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Kuca K, Jun D, Bajgar J.
    Drug Chem Toxicol; 2007 Jun 25; 30(1):31-40. PubMed ID: 17364862
    [Abstract] [Full Text] [Related]

  • 18. A comparison of reactivating and therapeutic efficacy of bispyridinium acetylcholinesterase reactivator KR-22934 with the oxime K203 and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J, Karasova JZ, Pavlikova R, Musilek K, Kuca K, Bajgar J, Jung YS.
    Toxicol Mech Methods; 2011 Mar 25; 21(3):241-5. PubMed ID: 21142778
    [Abstract] [Full Text] [Related]

  • 19. New quaternary pyridine aldoximes as casual antidotes against nerve agents intoxications.
    Kuca K, Bartosová L, Jun D, Patocka J, Cabal J, Kassa J, Kunesová G.
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Jun 25; 149(1):75-82. PubMed ID: 16170392
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase.
    de Koning MC, Horn G, Worek F, van Grol M.
    Chem Biol Interact; 2020 Aug 01; 326():109139. PubMed ID: 32454005
    [Abstract] [Full Text] [Related]

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