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607 related items for PubMed ID: 25846811

  • 1. Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells.
    Kawashima I, Mitsumori T, Nozaki Y, Yamamoto T, Shobu-Sueki Y, Nakajima K, Kirito K.
    Exp Hematol; 2015 Jul; 43(7):524-33.e1. PubMed ID: 25846811
    [Abstract] [Full Text] [Related]

  • 2. Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway.
    Lin CC, Yeh HH, Huang WL, Yan JJ, Lai WW, Su WP, Chen HH, Su WC.
    Am J Respir Cell Mol Biol; 2013 Aug; 49(2):241-50. PubMed ID: 23526220
    [Abstract] [Full Text] [Related]

  • 3. Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling.
    Fumarola C, Caffarra C, La Monica S, Galetti M, Alfieri RR, Cavazzoni A, Galvani E, Generali D, Petronini PG, Bonelli MA.
    Breast Cancer Res Treat; 2013 Aug; 141(1):67-78. PubMed ID: 23963659
    [Abstract] [Full Text] [Related]

  • 4. Metformin inhibits growth of human non-small cell lung cancer cells via liver kinase B-1-independent activation of adenosine monophosphate-activated protein kinase.
    Guo Q, Liu Z, Jiang L, Liu M, Ma J, Yang C, Han L, Nan K, Liang X.
    Mol Med Rep; 2016 Mar; 13(3):2590-6. PubMed ID: 26847819
    [Abstract] [Full Text] [Related]

  • 5. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [Abstract] [Full Text] [Related]

  • 6. LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.
    Li NS, Zou JR, Lin H, Ke R, He XL, Xiao L, Huang D, Luo L, Lv N, Luo Z.
    Tumour Biol; 2016 Jun; 37(6):8249-58. PubMed ID: 26718214
    [Abstract] [Full Text] [Related]

  • 7. PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway.
    Dokladda K, Green KA, Pan DA, Hardie DG.
    FEBS Lett; 2005 Jan 03; 579(1):236-40. PubMed ID: 15620719
    [Abstract] [Full Text] [Related]

  • 8. Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.
    Do MT, Kim HG, Khanal T, Choi JH, Kim DH, Jeong TC, Jeong HG.
    Toxicol Appl Pharmacol; 2013 Sep 01; 271(2):229-38. PubMed ID: 23707609
    [Abstract] [Full Text] [Related]

  • 9. ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer.
    Liu L, Zhang H, Sun L, Gao Y, Jin H, Liang S, Wang Y, Dong M, Shi Y, Li Z, Fan D.
    Int J Cancer; 2010 Aug 15; 127(4):820-9. PubMed ID: 19998339
    [Abstract] [Full Text] [Related]

  • 10. AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma.
    Kim MJ, Park IJ, Yun H, Kang I, Choe W, Kim SS, Ha J.
    J Biol Chem; 2010 May 07; 285(19):14617-27. PubMed ID: 20220132
    [Abstract] [Full Text] [Related]

  • 11. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
    Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H.
    Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093
    [Abstract] [Full Text] [Related]

  • 12. Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells.
    Hwang JT, Kim YM, Surh YJ, Baik HW, Lee SK, Ha J, Park OJ.
    Cancer Res; 2006 Oct 15; 66(20):10057-63. PubMed ID: 17047069
    [Abstract] [Full Text] [Related]

  • 13. Liver Kinase B1/AMP-Activated Protein Kinase Pathway Activation Attenuated the Progression of Endotoxemia in the Diabetic Mice.
    Yang Y, Dong R, Hu D, Chen Z, Fu M, Wang DW, Xu X, Tu L.
    Cell Physiol Biochem; 2017 Oct 15; 42(2):761-779. PubMed ID: 28628912
    [Abstract] [Full Text] [Related]

  • 14. The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL.
    Svojgr K, Kalina T, Kanderova V, Skopcova T, Brdicka T, Zuna J.
    Exp Hematol; 2012 May 15; 40(5):379-85. PubMed ID: 22269118
    [Abstract] [Full Text] [Related]

  • 15. Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties.
    MacDonald AF, Bettaieb A, Donohoe DR, Alani DS, Han A, Zhao Y, Whelan J.
    BMC Complement Altern Med; 2018 Jun 18; 18(1):188. PubMed ID: 29914450
    [Abstract] [Full Text] [Related]

  • 16. Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.
    Calviño E, Estañ MC, Sánchez-Martín C, Brea R, de Blas E, Boyano-Adánez Mdel C, Rial E, Aller P.
    J Pharmacol Exp Ther; 2014 Feb 18; 348(2):324-35. PubMed ID: 24307199
    [Abstract] [Full Text] [Related]

  • 17. Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.
    Sanli T, Rashid A, Liu C, Harding S, Bristow RG, Cutz JC, Singh G, Wright J, Tsakiridis T.
    Int J Radiat Oncol Biol Phys; 2010 Sep 01; 78(1):221-9. PubMed ID: 20615625
    [Abstract] [Full Text] [Related]

  • 18. AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.
    Zhang YL, Guo H, Zhang CS, Lin SY, Yin Z, Peng Y, Luo H, Shi Y, Lian G, Zhang C, Li M, Ye Z, Ye J, Han J, Li P, Wu JW, Lin SC.
    Cell Metab; 2013 Oct 01; 18(4):546-55. PubMed ID: 24093678
    [Abstract] [Full Text] [Related]

  • 19. An investigation of the effects of the MEK inhibitor U0126 on apoptosis in acute leukemia.
    James JA, Smith MA, Court EL, Yip C, Ching Y, Willson C, Smith JG.
    Hematol J; 2003 Oct 01; 4(6):427-32. PubMed ID: 14671615
    [Abstract] [Full Text] [Related]

  • 20. Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.
    Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F.
    Mol Cancer Res; 2008 Jan 01; 6(1):42-52. PubMed ID: 18234961
    [Abstract] [Full Text] [Related]


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