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PUBMED FOR HANDHELDS

Journal Abstract Search


626 related items for PubMed ID: 25852085

  • 1. Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.
    Isidori AM, Cornacchione M, Barbagallo F, Di Grazia A, Barrios F, Fassina L, Monaco L, Giannetta E, Gianfrilli D, Garofalo S, Zhang X, Chen X, Xiang YK, Lenzi A, Pellegrini M, Naro F.
    Cardiovasc Res; 2015 Jun 01; 106(3):408-20. PubMed ID: 25852085
    [Abstract] [Full Text] [Related]

  • 2. Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes.
    Shi Q, Li M, Mika D, Fu Q, Kim S, Phan J, Shen A, Vandecasteele G, Xiang YK.
    Cardiovasc Res; 2017 May 01; 113(6):656-670. PubMed ID: 28339772
    [Abstract] [Full Text] [Related]

  • 3. Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy.
    Perera RK, Sprenger JU, Steinbrecher JH, Hübscher D, Lehnart SE, Abesser M, Schuh K, El-Armouche A, Nikolaev VO.
    Circ Res; 2015 Apr 10; 116(8):1304-11. PubMed ID: 25688144
    [Abstract] [Full Text] [Related]

  • 4. Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts.
    West TM, Wang Q, Deng B, Zhang Y, Barbagallo F, Reddy GR, Chen D, Phan KS, Xu B, Isidori A, Xiang YK.
    J Am Heart Assoc; 2019 Aug 06; 8(15):e012273. PubMed ID: 31311394
    [Abstract] [Full Text] [Related]

  • 5. PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signalling in cardiac myocytes.
    Bedioune I, Lefebvre F, Lechêne P, Varin A, Domergue V, Kapiloff MS, Fischmeister R, Vandecasteele G.
    Cardiovasc Res; 2018 Sep 01; 114(11):1499-1511. PubMed ID: 29733383
    [Abstract] [Full Text] [Related]

  • 6. Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway.
    Zhao CY, Greenstein JL, Winslow RL.
    J Mol Cell Cardiol; 2015 Nov 01; 88():29-38. PubMed ID: 26388264
    [Abstract] [Full Text] [Related]

  • 7. Roles of phosphodiesterases in the regulation of the cardiac cyclic nucleotide cross-talk signaling network.
    Zhao CY, Greenstein JL, Winslow RL.
    J Mol Cell Cardiol; 2016 Feb 01; 91():215-27. PubMed ID: 26773602
    [Abstract] [Full Text] [Related]

  • 8. Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
    Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A.
    J Am Coll Cardiol; 2013 Oct 22; 62(17):1596-606. PubMed ID: 23810893
    [Abstract] [Full Text] [Related]

  • 9. PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.
    Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E, Kass DA.
    Basic Res Cardiol; 2010 May 22; 105(3):337-47. PubMed ID: 20107996
    [Abstract] [Full Text] [Related]

  • 10. Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.
    Wang H, Kohr MJ, Traynham CJ, Ziolo MT.
    J Mol Cell Cardiol; 2009 Aug 22; 47(2):304-14. PubMed ID: 19345227
    [Abstract] [Full Text] [Related]

  • 11. PDE4B mediates local feedback regulation of β₁-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes.
    Mika D, Richter W, Westenbroek RE, Catterall WA, Conti M.
    J Cell Sci; 2014 Mar 01; 127(Pt 5):1033-42. PubMed ID: 24413164
    [Abstract] [Full Text] [Related]

  • 12. A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.
    Fu Q, Kim S, Soto D, De Arcangelis V, DiPilato L, Liu S, Xu B, Shi Q, Zhang J, Xiang YK.
    J Biol Chem; 2014 May 23; 289(21):14771-81. PubMed ID: 24713698
    [Abstract] [Full Text] [Related]

  • 13. Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
    Takimoto E, Belardi D, Tocchetti CG, Vahebi S, Cormaci G, Ketner EA, Moens AL, Champion HC, Kass DA.
    Circulation; 2007 Apr 24; 115(16):2159-67. PubMed ID: 17420342
    [Abstract] [Full Text] [Related]

  • 14. Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway.
    Mongillo M, Tocchetti CG, Terrin A, Lissandron V, Cheung YF, Dostmann WR, Pozzan T, Kass DA, Paolocci N, Houslay MD, Zaccolo M.
    Circ Res; 2006 Feb 03; 98(2):226-34. PubMed ID: 16357307
    [Abstract] [Full Text] [Related]

  • 15. PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β2 adrenoceptor-mediated effects.
    Soler F, Fernández-Belda F, Pérez-Schindler J, Handschin C, Fuente T, Hernandez-Cascales J.
    Exp Biol Med (Maywood); 2015 Sep 03; 240(9):1205-13. PubMed ID: 25432985
    [Abstract] [Full Text] [Related]

  • 16. Dynamic protein kinase a activities induced by beta-adrenoceptors dictate signaling propagation for substrate phosphorylation and myocyte contraction.
    Soto D, De Arcangelis V, Zhang J, Xiang Y.
    Circ Res; 2009 Mar 27; 104(6):770-9. PubMed ID: 19213958
    [Abstract] [Full Text] [Related]

  • 17. Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β1-adrenoceptor-mediated inotropic response.
    Cosson MV, Hiis HG, Moltzau LR, Levy FO, Krobert KA.
    J Mol Cell Cardiol; 2019 Jun 27; 131():132-145. PubMed ID: 31009605
    [Abstract] [Full Text] [Related]

  • 18. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling.
    Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S.
    Circ Res; 2006 Nov 10; 99(10):1084-91. PubMed ID: 17038640
    [Abstract] [Full Text] [Related]

  • 19. Insulin induces IRS2-dependent and GRK2-mediated β2AR internalization to attenuate βAR signaling in cardiomyocytes.
    Fu Q, Xu B, Parikh D, Cervantes D, Xiang YK.
    Cell Signal; 2015 Mar 10; 27(3):707-15. PubMed ID: 25460042
    [Abstract] [Full Text] [Related]

  • 20. PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways.
    Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A.
    Am J Physiol Heart Circ Physiol; 2014 Apr 15; 306(8):H1246-52. PubMed ID: 24531807
    [Abstract] [Full Text] [Related]


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