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Journal Abstract Search

647 related items for PubMed ID: 25866240

  • 1. Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors.
    Chen Z, Wang ZC, Yan XQ, Wang PF, Lu XY, Chen LW, Zhu HL, Zhang HW.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1947-51. PubMed ID: 25866240
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Abdelgawad MA, Bakr RB, Omar HA.
    Bioorg Chem; 2017 Oct 01; 74():82-90. PubMed ID: 28772160
    [Abstract] [Full Text] [Related]

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  • 4. Design, synthesis and biological evaluation of pyridine acyl sulfonamide derivatives as novel COX-2 inhibitors.
    Lu X, Zhang H, Li X, Chen G, Li QS, Luo Y, Ruan BF, Chen XW, Zhu HL.
    Bioorg Med Chem; 2011 Nov 15; 19(22):6827-32. PubMed ID: 22000948
    [Abstract] [Full Text] [Related]

  • 5. 1,3,4-Trisubstituted pyrazole analogues as promising anti-inflammatory agents.
    Alegaon SG, Alagawadi KR, Garg MK, Dushyant K, Vinod D.
    Bioorg Chem; 2014 Jun 15; 54():51-9. PubMed ID: 24793214
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  • 7. Synthesis and biological evaluation of some new 2-pyrazolines bearing benzene sulfonamide moiety as potential anti-inflammatory and anti-cancer agents.
    Bano S, Javed K, Ahmad S, Rathish IG, Singh S, Alam MS.
    Eur J Med Chem; 2011 Dec 15; 46(12):5763-8. PubMed ID: 22019186
    [Abstract] [Full Text] [Related]

  • 8. Exploration of isoxazole analogs: Synthesis, COX inhibition, anticancer screening, 3D multicellular tumor spheroids, and molecular modeling.
    Hawash M, Abdallah S, Abudayyak M, Melhem Y, Abu Shamat M, Aghbar M, Çapan I, Abualhasan M, Kumar A, Kamiński M, Góral T, Dominiak PM, Sobuh S.
    Eur J Med Chem; 2024 May 05; 271():116397. PubMed ID: 38626522
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent anti-inflammatory agents and cyclooxygenase inhibitors.
    Chandna N, Kumar S, Kaushik P, Kaushik D, Roy SK, Gupta GK, Jachak SM, Kapoor JK, Sharma PK.
    Bioorg Med Chem; 2013 Aug 01; 21(15):4581-90. PubMed ID: 23769654
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK, Singh VP, Yadav P, Gupta G, Singh A, Goel RK, Shinde P, Mohan CG.
    Bioorg Chem; 2014 Oct 01; 56():8-15. PubMed ID: 24893208
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2-hydroxyphenyl Moiety: A Series of Novel MMP-2 Inhibitors.
    Wang PF, Qiu HY, Baloch SK, Gong HB, Wang ZC, Zhu HL.
    Chem Biol Drug Des; 2015 Dec 01; 86(6):1405-10. PubMed ID: 26061284
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular docking study.
    Abdel-Aziz AA, El-Azab AS, AlSaif NA, Alanazi MM, El-Gendy MA, Obaidullah AJ, Alkahtani HM, Almehizia AA, Al-Suwaidan IA.
    J Enzyme Inhib Med Chem; 2020 Dec 13; 35(1):610-621. PubMed ID: 32013633
    [Abstract] [Full Text] [Related]

  • 14. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 13; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 15. Design and biological evaluation of novel hybrids of 1, 5-diarylpyrazole and Chrysin for selective COX-2 inhibition.
    Ren SZ, Wang ZC, Zhu XH, Zhu D, Li Z, Shen FQ, Duan YT, Cao H, Zhao J, Zhu HL.
    Bioorg Med Chem; 2018 Aug 07; 26(14):4264-4275. PubMed ID: 30031652
    [Abstract] [Full Text] [Related]

  • 16. Design and synthesis of N-phenylacetyl (sulfonyl) 4,5-dihydropyrazole derivatives as potential antitumor agents.
    Liu XH, Ruan BF, Liu JX, Song BA, Jing LH, Li J, Yang Y, Zhu HL, Qi XB.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):2916-20. PubMed ID: 21486698
    [Abstract] [Full Text] [Related]

  • 17. Coumarin sulfonamides derivatives as potent and selective COX-2 inhibitors with efficacy in suppressing cancer proliferation and metastasis.
    Lu XY, Wang ZC, Ren SZ, Shen FQ, Man RJ, Zhu HL.
    Bioorg Med Chem Lett; 2016 Aug 01; 26(15):3491-8. PubMed ID: 27349331
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities.
    Abd El Razik HA, Mroueh M, Faour WH, Shebaby WN, Daher CF, Ashour HMA, Ragab HM.
    Chem Biol Drug Des; 2017 Jul 01; 90(1):83-96. PubMed ID: 28032452
    [Abstract] [Full Text] [Related]

  • 19. Isomeric acetoxy analogs of celecoxib and their evaluation as cyclooxygenase inhibitors.
    Abdur Rahim M, Praveen Rao PN, Bhardwaj A, Kaur J, Huang Z, Knaus EE.
    Bioorg Med Chem Lett; 2011 Oct 15; 21(20):6074-80. PubMed ID: 21890358
    [Abstract] [Full Text] [Related]

  • 20. 3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.
    Ranatunge RR, Earl RA, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Schwalb DJ, Young DV, Zemtseva IS.
    Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6049-52. PubMed ID: 15546727
    [Abstract] [Full Text] [Related]

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