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298 related items for PubMed ID: 25870278

  • 1. Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase.
    Qvartskhava N, Lang PA, Görg B, Pozdeev VI, Ortiz MP, Lang KS, Bidmon HJ, Lang E, Leibrock CB, Herebian D, Bode JG, Lang F, Häussinger D.
    Proc Natl Acad Sci U S A; 2015 Apr 28; 112(17):5521-6. PubMed ID: 25870278
    [Abstract] [Full Text] [Related]

  • 2. Hepatic glutamine synthetase augmentation enhances ammonia detoxification.
    Soria LR, Nitzahn M, De Angelis A, Khoja S, Attanasio S, Annunziata P, Palmer DJ, Ng P, Lipshutz GS, Brunetti-Pierri N.
    J Inherit Metab Dis; 2019 Nov 28; 42(6):1128-1135. PubMed ID: 30724386
    [Abstract] [Full Text] [Related]

  • 3. Taurine transporter (TauT) deficiency impairs ammonia detoxification in mouse liver.
    Qvartskhava N, Jin CJ, Buschmann T, Albrecht U, Bode JG, Monhasery N, Oenarto J, Bidmon HJ, Görg B, Häussinger D.
    Proc Natl Acad Sci U S A; 2019 Mar 26; 116(13):6313-6318. PubMed ID: 30862735
    [Abstract] [Full Text] [Related]

  • 4. Glutamine synthetase in brain: effect of ammonia.
    Suárez I, Bodega G, Fernández B.
    Neurochem Int; 2002 Mar 26; 41(2-3):123-42. PubMed ID: 12020613
    [Abstract] [Full Text] [Related]

  • 5. Novel aspects of glutamine synthetase in ammonia homeostasis.
    Zhou Y, Eid T, Hassel B, Danbolt NC.
    Neurochem Int; 2020 Nov 26; 140():104809. PubMed ID: 32758585
    [Abstract] [Full Text] [Related]

  • 6. Developmental study of hepatic glutamine synthetase in a mouse model of congenital hyperammonemia.
    Skarpetas A, Mawal Y, Qureshi IA.
    Biochem Mol Biol Int; 1997 Sep 26; 43(1):133-9. PubMed ID: 9315291
    [Abstract] [Full Text] [Related]

  • 7. Ornithine phenylacetate targets alterations in the expression and activity of glutamine synthase and glutaminase to reduce ammonia levels in bile duct ligated rats.
    Jover-Cobos M, Noiret L, Lee K, Sharma V, Habtesion A, Romero-Gomez M, Davies N, Jalan R.
    J Hepatol; 2014 Mar 26; 60(3):545-53. PubMed ID: 24512823
    [Abstract] [Full Text] [Related]

  • 8. Delivery of glutamine synthetase gene by baculovirus vectors: a proof of concept for the treatment of acute hyperammonemia.
    Torres-Vega MA, Vargas-Jerónimo RY, Montiel-Martínez AG, Muñoz-Fuentes RM, Zamorano-Carrillo A, Pastor AR, Palomares LA.
    Gene Ther; 2015 Jan 26; 22(1):58-64. PubMed ID: 25338921
    [Abstract] [Full Text] [Related]

  • 9. Impaired novelty acquisition and synaptic plasticity in congenital hyperammonemia caused by hepatic glutamine synthetase deficiency.
    Chepkova AN, Sergeeva OA, Görg B, Haas HL, Klöcker N, Häussinger D.
    Sci Rep; 2017 Jan 09; 7():40190. PubMed ID: 28067279
    [Abstract] [Full Text] [Related]

  • 10. Gene Therapy for Treatment of Chronic Hyperammonemia in a Rat Model of Hepatic Encephalopathy.
    Espíritu-Ramírez P, Ortega-Balderas NY, Sevilla-Tapia L, Montiel-Martínez AG, Pastor-Flores AR, Palomares LA, Torres-Vega MA.
    Ann Hepatol; 2018 Oct 16; 17(6):1026-1034. PubMed ID: 30600292
    [Abstract] [Full Text] [Related]

  • 11. Lipopolysaccharide-induced tyrosine nitration and inactivation of hepatic glutamine synthetase in the rat.
    Görg B, Wettstein M, Metzger S, Schliess F, Häussinger D.
    Hepatology; 2005 May 16; 41(5):1065-73. PubMed ID: 15830392
    [Abstract] [Full Text] [Related]

  • 12. DNA-Encoded Glutamine Synthetase Enzyme as Ammonia-Lowering Therapeutic for Hyperammonemia.
    Khoshnejad M, Dia Y, Patel A, Xu Z, Zhu X, Yun K, Wojtak K, Qureshi R, Humeau L, Muthumani K, Weiner DB.
    Nucleic Acid Ther; 2020 Dec 16; 30(6):379-391. PubMed ID: 32907467
    [Abstract] [Full Text] [Related]

  • 13. Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapy.
    Brusilow SW, Koehler RC, Traystman RJ, Cooper AJ.
    Neurotherapeutics; 2010 Oct 16; 7(4):452-70. PubMed ID: 20880508
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  • 17. Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.
    Dai W, Shen J, Yan J, Bott AJ, Maimouni S, Daguplo HQ, Wang Y, Khayati K, Guo JY, Zhang L, Wang Y, Valvezan A, Ding WX, Chen X, Su X, Gao S, Zong WX.
    J Clin Invest; 2022 Dec 15; 132(24):. PubMed ID: 36256480
    [Abstract] [Full Text] [Related]

  • 18. Glutamine synthetase deficiency in murine astrocytes results in neonatal death.
    He Y, Hakvoort TB, Vermeulen JL, Labruyère WT, De Waart DR, Van Der Hel WS, Ruijter JM, Uylings HB, Lamers WH.
    Glia; 2010 Apr 15; 58(6):741-54. PubMed ID: 20140959
    [Abstract] [Full Text] [Related]

  • 19. Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle.
    Desjardins P, Rao KV, Michalak A, Rose C, Butterworth RF.
    Metab Brain Dis; 1999 Dec 15; 14(4):273-80. PubMed ID: 10850554
    [Abstract] [Full Text] [Related]

  • 20. Ammonia and autophagy: An emerging relationship with implications for disorders with hyperammonemia.
    Soria LR, Brunetti-Pierri N.
    J Inherit Metab Dis; 2019 Nov 15; 42(6):1097-1104. PubMed ID: 30671986
    [Abstract] [Full Text] [Related]

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