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Journal Abstract Search

246 related items for PubMed ID: 25871012

  • 1. Design, synthesis, and pharmacological evaluation of highly potent and selective dipeptidyl peptidase-4 inhibitors.
    Jiang T, Zhou Y, Zhu J, Chen Z, Sun P, Zhang Q, Wang Z, Shao Q, Jiang X, Li B, Wang H, Zhu W, Shen J.
    Arch Pharm (Weinheim); 2015 Jun; 348(6):399-407. PubMed ID: 25871012
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors.
    Liu Y, Si M, Tang L, Shangguan S, Wu H, Li J, Wu P, Ma X, Liu T, Hu Y.
    Bioorg Med Chem; 2013 Sep 15; 21(18):5679-87. PubMed ID: 23938053
    [Abstract] [Full Text] [Related]

  • 3. Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors.
    Nitta A, Fujii H, Sakami S, Satoh M, Nakaki J, Satoh S, Kumagai H, Kawai H.
    Bioorg Med Chem Lett; 2012 Dec 01; 22(23):7036-40. PubMed ID: 23072865
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin.
    Dong J, Gong Y, Liu J, Chen X, Wen X, Sun H.
    Bioorg Med Chem; 2014 Feb 15; 22(4):1383-93. PubMed ID: 24457090
    [Abstract] [Full Text] [Related]

  • 5. Discovering novel α-aminoacyl-containing proline derivatives with potent and selective inhibitory activity against dipeptidyl peptidase IV: design, synthesis, biological evaluation, and molecular modeling.
    Zhang X, Wang J, Su M, Li Z, Li J, Li J, Liu H.
    Chem Biol Drug Des; 2012 Dec 15; 80(6):843-52. PubMed ID: 22726613
    [Abstract] [Full Text] [Related]

  • 6. Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation.
    Xing J, Li Q, Zhang S, Liu H, Zhao L, Cheng H, Zhang Y, Zhou J, Zhang H.
    Chem Biol Drug Des; 2014 Sep 15; 84(3):364-77. PubMed ID: 24674599
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of triazole based uracil derivatives as novel DPP-4 inhibitors.
    Li Q, Han L, Zhang B, Zhou J, Zhang H.
    Org Biomol Chem; 2016 Oct 12; 14(40):9598-9611. PubMed ID: 27714283
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, structure-activity relationships, and docking studies of 1-(γ-1,2,3-triazol substituted prolyl)-(S)-3,3-difluoropyrrolidines as a novel series of potent and selective dipeptidyl peptidase-4 inhibitors.
    Zhang L, Su M, Li J, Ji X, Wang J, Li Z, Li J, Liu H.
    Chem Biol Drug Des; 2013 Feb 12; 81(2):198-207. PubMed ID: 22994702
    [Abstract] [Full Text] [Related]

  • 9. Design, Synthesis and Biological Evaluation of Spiro Cyclohexane-1,2- Quinazoline Derivatives as Potent Dipeptidyl Peptidase IV Inhibitors.
    Syam YM, El-Karim SSA, Nasr T, Elseginy SA, Anwar MM, Kamel MM, Ali HF.
    Mini Rev Med Chem; 2019 Feb 12; 19(3):250-269. PubMed ID: 28847268
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, biological evaluation, and docking studies of (s)-phenylalanine derivatives with a 2-cyanopyrrolidine moiety as potent dipeptidyl peptidase 4 inhibitors.
    Liu Y, Wu Y, Wu H, Tang L, Wu P, Liu T, Hu Y.
    Chem Biol Drug Des; 2013 Aug 12; 82(2):140-6. PubMed ID: 23530834
    [Abstract] [Full Text] [Related]

  • 11. Discovery of triazole-based uracil derivatives bearing amide moieties as novel dipeptidyl peptidase-IV inhibitors.
    Deng X, Han L, Zhou J, Zhang H, Li Q.
    Bioorg Chem; 2017 Dec 12; 75():357-367. PubMed ID: 29096096
    [Abstract] [Full Text] [Related]

  • 12. Critical role of renal dipeptidyl peptidase-4 in ameliorating kidney injury induced by saxagliptin in Dahl salt-sensitive hypertensive rats.
    Sakai M, Uchii M, Myojo K, Kitayama T, Kunori S.
    Eur J Pharmacol; 2015 Aug 15; 761():109-15. PubMed ID: 25936515
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and potent inhibitory activities of carboxybenzyl-substituted 8-(3-(R)-aminopiperidin-1-yl)-7-(2-chloro/cyanobenzyl)-3-methyl-3,7-dihydro-purine-2,6-diones as dipeptidyl peptidase IV (DPP-IV) inhibitors.
    Mo DW, Dong S, Sun H, Chen JS, Pang JX, Xi BM, Chen WH.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1872-5. PubMed ID: 25838146
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, evaluation and molecular docking of thiazolopyrimidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2012 Dec 01; 80(6):918-28. PubMed ID: 22943413
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, Biological Evaluation, and Molecular Docking of (R)-2-((8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-en-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzonitrile as Dipeptidyl Peptidase IV Inhibitors.
    Ran Y, Pei H, Shao M, Chen L.
    Chem Biol Drug Des; 2016 Feb 01; 87(2):290-5. PubMed ID: 26426933
    [Abstract] [Full Text] [Related]

  • 16. Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.
    Li Q, Zhou M, Han L, Cao Q, Wang X, Zhao L, Zhou J, Zhang H.
    Chem Biol Drug Des; 2015 Oct 01; 86(4):849-56. PubMed ID: 25787859
    [Abstract] [Full Text] [Related]

  • 17. Discovery of highly potent DPP-4 inhibitors by hybrid compound design based on linagliptin and alogliptin.
    Lai ZW, Li C, Liu J, Kong L, Wen X, Sun H.
    Eur J Med Chem; 2014 Aug 18; 83():547-60. PubMed ID: 24996141
    [Abstract] [Full Text] [Related]

  • 18. Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.
    Deng X, Shen J, Zhu H, Xiao J, Sun R, Xie F, Lam C, Wang J, Qiao Y, Tavallaie MS, Hu Y, Du Y, Li J, Fu L, Jiang F.
    Bioorg Med Chem; 2018 Feb 15; 26(4):903-912. PubMed ID: 29373269
    [Abstract] [Full Text] [Related]

  • 19. Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.
    Nordhoff S, Cerezo-Gálvez S, Deppe H, Hill O, López-Canet M, Rummey C, Thiemann M, Matassa VG, Edwards PJ, Feurer A.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4201-3. PubMed ID: 19515557
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
    Patel BD, Bhadada SV, Ghate MD.
    Bioorg Chem; 2017 Jun 01; 72():345-358. PubMed ID: 28302310
    [Abstract] [Full Text] [Related]

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