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Journal Abstract Search

160 related items for PubMed ID: 25882218

  • 1. Mechanisms of bacterial acetohydroxyacid synthase (AHAS) and specific inhibitors of Mycobacterium tuberculosis AHAS as potential drug candidates against tuberculosis.
    Gokhale K, Tilak B.
    Curr Drug Targets; 2015; 16(7):689-99. PubMed ID: 25882218
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  • 2. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ, Yu YG, Hahn HG, Choi JD, Yoon MY.
    FEBS Lett; 2005 Aug 29; 579(21):4903-10. PubMed ID: 16111681
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  • 3. Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases.
    Chipman D, Barak Z, Schloss JV.
    Biochim Biophys Acta; 1998 Jun 29; 1385(2):401-19. PubMed ID: 9655946
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  • 4. Acetohydroxyacid synthase: a target for antimicrobial drug discovery.
    Pue N, Guddat LW.
    Curr Pharm Des; 2014 Jun 29; 20(5):740-53. PubMed ID: 23688082
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  • 5. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status.
    Gedi V, Yoon MY.
    FEBS J; 2012 Mar 29; 279(6):946-63. PubMed ID: 22284339
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  • 6. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY.
    Biosci Biotechnol Biochem; 2010 Mar 29; 74(11):2281-6. PubMed ID: 21071847
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  • 7. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
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  • 8. Development of potent chemical antituberculosis agents targeting Mycobacterium tuberculosis acetohydroxyacid synthase.
    Jung IP, Ha NR, Lee SC, Ryoo SW, Yoon MY.
    Int J Antimicrob Agents; 2016 Sep 01; 48(3):247-58. PubMed ID: 27451857
    [Abstract] [Full Text] [Related]

  • 9. Discovery of novel acetohydroxyacid synthase inhibitors as active agents against Mycobacterium tuberculosis by virtual screening and bioassay.
    Wang D, Zhu X, Cui C, Dong M, Jiang H, Li Z, Liu Z, Zhu W, Wang JG.
    J Chem Inf Model; 2013 Feb 25; 53(2):343-53. PubMed ID: 23316686
    [Abstract] [Full Text] [Related]

  • 10. Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Moon JY, Lee SC, Ryoo SW, Yoon MY.
    Biochim Biophys Acta; 2015 Oct 25; 1854(10 Pt A):1338-50. PubMed ID: 25988243
    [Abstract] [Full Text] [Related]

  • 11. Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Gedi V, Lee SC, Koh SH, Yoon MY.
    Enzyme Microb Technol; 2013 Sep 10; 53(4):243-9. PubMed ID: 23931689
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  • 14. Cloning, characterization and evaluation of potent inhibitors of Shigella sonnei acetohydroxyacid synthase catalytic subunit.
    Lim WM, Baig IJ, La IJ, Choi JD, Kim DE, Kim SK, Hyun JW, Kim G, Kang CH, Kim YJ, Yoon MY.
    Biochim Biophys Acta; 2011 Dec 10; 1814(12):1825-31. PubMed ID: 22015678
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  • 16. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 10; 95(7):1411-21. PubMed ID: 23523771
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  • 18. In vitro and ex vivo activity of new derivatives of acetohydroxyacid synthase inhibitors against Mycobacterium tuberculosis and non-tuberculous mycobacteria.
    Sohn H, Lee KS, Ko YK, Ryu JW, Woo JC, Koo DW, Shin SJ, Ahn SJ, Shin AR, Song CH, Jo EK, Park JK, Kim HJ.
    Int J Antimicrob Agents; 2008 Jun 10; 31(6):567-71. PubMed ID: 18337064
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  • 19. Biochemical and transcription analysis of acetohydroxyacid synthase isoforms in Mycobacterium tuberculosis identifies these enzymes as potential targets for drug development.
    Singh V, Chandra D, Srivastava BS, Srivastava R.
    Microbiology (Reading); 2011 Jan 10; 157(Pt 1):29-37. PubMed ID: 20884690
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