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Journal Abstract Search

200 related items for PubMed ID: 25888115

  • 1. C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.
    Gardner A, Sanguinetti MC.
    Mol Pharmacol; 2015 Jul; 88(1):19-28. PubMed ID: 25888115
    [Abstract] [Full Text] [Related]

  • 2. A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator.
    Perry M, Sanguinetti MC.
    Mol Pharmacol; 2008 Apr; 73(4):1044-51. PubMed ID: 18162604
    [Abstract] [Full Text] [Related]

  • 3. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
    Perry M, Sachse FB, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2007 Aug 21; 104(34):13827-32. PubMed ID: 17693551
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  • 4. Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243.
    Wu W, Gardner A, Sanguinetti MC.
    Mol Pharmacol; 2015 Aug 21; 87(3):401-9. PubMed ID: 25519838
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  • 5. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.
    Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2009 Nov 24; 106(47):20075-80. PubMed ID: 19892732
    [Abstract] [Full Text] [Related]

  • 6. Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel.
    Kang J, Chen XL, Wang H, Ji J, Cheng H, Incardona J, Reynolds W, Viviani F, Tabart M, Rampe D.
    Mol Pharmacol; 2005 Mar 24; 67(3):827-36. PubMed ID: 15548764
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  • 10. Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea].
    Hansen RS, Diness TG, Christ T, Wettwer E, Ravens U, Olesen SP, Grunnet M.
    Mol Pharmacol; 2006 Oct 24; 70(4):1319-29. PubMed ID: 16825484
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  • 11. Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.
    Clarke CE, Hill AP, Zhao J, Kondo M, Subbiah RN, Campbell TJ, Vandenberg JI.
    J Physiol; 2006 Jun 01; 573(Pt 2):291-304. PubMed ID: 16556651
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  • 12. The Link between Inactivation and High-Affinity Block of hERG1 Channels.
    Wu W, Gardner A, Sanguinetti MC.
    Mol Pharmacol; 2015 Jun 01; 87(6):1042-50. PubMed ID: 25855787
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  • 13. An intracellular hydrophobic nexus critical for hERG1 channel slow deactivation.
    Stevens-Sostre WA, Flores-Aldama L, Bustos D, Li J, Morais-Cabral JH, Delemotte L, Robertson GA.
    Biophys J; 2024 Jul 16; 123(14):2024-2037. PubMed ID: 38219015
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  • 14. Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels.
    Larsen AP, Bentzen BH, Grunnet M.
    Br J Pharmacol; 2010 Oct 16; 161(3):614-28. PubMed ID: 20880400
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  • 16. Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.
    Gardner A, Wu W, Thomson S, Zangerl-Plessl EM, Stary-Weinzinger A, Sanguinetti MC.
    Mol Pharmacol; 2017 Oct 16; 92(4):437-450. PubMed ID: 28705808
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  • 18. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
    Durdagi S, Guo J, Lees-Miller JP, Noskov SY, Duff HJ.
    J Pharmacol Exp Ther; 2012 Aug 16; 342(2):441-52. PubMed ID: 22573844
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  • 19. Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.
    Ng CA, Phan K, Hill AP, Vandenberg JI, Perry MD.
    J Biol Chem; 2014 Sep 12; 289(37):25822-32. PubMed ID: 25074935
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