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Journal Abstract Search

184 related items for PubMed ID: 25895103

  • 1.
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  • 2. Mutagenesis analysis of the rGTP-specific binding site of hepatitis C virus RNA-dependent RNA polymerase.
    Cai Z, Yi M, Zhang C, Luo G.
    J Virol; 2005 Sep; 79(18):11607-17. PubMed ID: 16140738
    [Abstract] [Full Text] [Related]

  • 3. A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A.
    Ranjith-Kumar CT, Wen Y, Baxter N, Bhardwaj K, Cheng Kao C.
    PLoS One; 2011 Sep; 6(7):e22575. PubMed ID: 21799903
    [Abstract] [Full Text] [Related]

  • 4. Mutations in NS5B polymerase of hepatitis C virus: impacts on in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture.
    Cheney IW, Naim S, Lai VC, Dempsey S, Bellows D, Walker MP, Shim JH, Horscroft N, Hong Z, Zhong W.
    Virology; 2002 Jun 05; 297(2):298-306. PubMed ID: 12083828
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  • 6. Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo.
    Schult P, Nattermann M, Lauber C, Seitz S, Lohmann V.
    J Virol; 2019 Oct 01; 93(19):. PubMed ID: 31315989
    [Abstract] [Full Text] [Related]

  • 7. Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.
    Han SH, Kim SJ, Kim EJ, Kim TE, Moon JS, Kim GW, Lee SH, Cho K, Yoo JS, Son WS, Rhee JK, Han SH, Oh JW.
    J Virol; 2014 Oct 01; 88(19):11240-52. PubMed ID: 25031343
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  • 8. Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase.
    Kukolj G, McGibbon GA, McKercher G, Marquis M, Lefèbvre S, Thauvette L, Gauthier J, Goulet S, Poupart MA, Beaulieu PL.
    J Biol Chem; 2005 Nov 25; 280(47):39260-7. PubMed ID: 16188890
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  • 10. Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405.
    Scrima N, Caillet-Saguy C, Ventura M, Harrus D, Astier-Gin T, Bressanelli S.
    J Virol; 2012 Jul 25; 86(13):7107-17. PubMed ID: 22532694
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  • 12. Hepatitis C virus RNA replication requires a conserved structural motif within the transmembrane domain of the NS5B RNA-dependent RNA polymerase.
    Brass V, Gouttenoire J, Wahl A, Pal Z, Blum HE, Penin F, Moradpour D.
    J Virol; 2010 Nov 25; 84(21):11580-4. PubMed ID: 20739529
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  • 14. Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor.
    Howe AY, Cheng H, Thompson I, Chunduru SK, Herrmann S, O'Connell J, Agarwal A, Chopra R, Del Vecchio AM.
    Antimicrob Agents Chemother; 2006 Dec 25; 50(12):4103-13. PubMed ID: 16940072
    [Abstract] [Full Text] [Related]

  • 15. Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.
    Dhanak D, Duffy KJ, Johnston VK, Lin-Goerke J, Darcy M, Shaw AN, Gu B, Silverman C, Gates AT, Nonnemacher MR, Earnshaw DL, Casper DJ, Kaura A, Baker A, Greenwood C, Gutshall LL, Maley D, DelVecchio A, Macarron R, Hofmann GA, Alnoah Z, Cheng HY, Chan G, Khandekar S, Keenan RM, Sarisky RT.
    J Biol Chem; 2002 Oct 11; 277(41):38322-7. PubMed ID: 12167642
    [Abstract] [Full Text] [Related]

  • 16. Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus.
    Hang JQ, Yang Y, Harris SF, Leveque V, Whittington HJ, Rajyaguru S, Ao-Ieong G, McCown MF, Wong A, Giannetti AM, Le Pogam S, Talamás F, Cammack N, Nájera I, Klumpp K.
    J Biol Chem; 2009 Jun 05; 284(23):15517-29. PubMed ID: 19246450
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  • 17. De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus.
    Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, Lemm J, Colonno RJ.
    J Virol; 2000 Jan 05; 74(2):851-63. PubMed ID: 10623748
    [Abstract] [Full Text] [Related]

  • 18. A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication.
    You S, Stump DD, Branch AD, Rice CM.
    J Virol; 2004 Feb 05; 78(3):1352-66. PubMed ID: 14722290
    [Abstract] [Full Text] [Related]

  • 19. Development of intergenotypic chimeric replicons to determine the broad-spectrum antiviral activities of hepatitis C virus polymerase inhibitors.
    Herlihy KJ, Graham JP, Kumpf R, Patick AK, Duggal R, Shi ST.
    Antimicrob Agents Chemother; 2008 Oct 05; 52(10):3523-31. PubMed ID: 18694956
    [Abstract] [Full Text] [Related]

  • 20. The hepatitis C virus core protein can modulate RNA-dependent RNA synthesis by the 2a polymerase.
    Wen Y, Cheng Kao C.
    Virus Res; 2014 Aug 30; 189():165-76. PubMed ID: 24874198
    [Abstract] [Full Text] [Related]

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