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2. Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion. Martin JE, Nguyen TT, Grunseich C, Nofziger JH, Lee PR, Fields D, Fischbeck KH, Foran E. J Neurosci; 2017 May 24; 37(21):5309-5318. PubMed ID: 28450545 [Abstract] [Full Text] [Related]
3. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy. Sison SL, Patitucci TN, Seminary ER, Villalon E, Lorson CL, Ebert AD. Hum Mol Genet; 2017 Sep 01; 26(17):3409-3420. PubMed ID: 28637335 [Abstract] [Full Text] [Related]
4. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog. Ohuchi K, Funato M, Kato Z, Seki J, Kawase C, Tamai Y, Ono Y, Nagahara Y, Noda Y, Kameyama T, Ando S, Tsuruma K, Shimazawa M, Hara H, Kaneko H. Stem Cells Transl Med; 2016 Feb 01; 5(2):152-63. PubMed ID: 26683872 [Abstract] [Full Text] [Related]
5. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology. Bowerman M, Murray LM, Beauvais A, Pinheiro B, Kothary R. Neuromuscul Disord; 2012 Mar 01; 22(3):263-76. PubMed ID: 22071333 [Abstract] [Full Text] [Related]
6. Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice. Dominguez E, Marais T, Chatauret N, Benkhelifa-Ziyyat S, Duque S, Ravassard P, Carcenac R, Astord S, Pereira de Moura A, Voit T, Barkats M. Hum Mol Genet; 2011 Feb 15; 20(4):681-93. PubMed ID: 21118896 [Abstract] [Full Text] [Related]
7. Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems. Ohuchi K, Funato M, Yoshino Y, Ando S, Inagaki S, Sato A, Kawase C, Seki J, Saito T, Nishio H, Nakamura S, Shimazawa M, Kaneko H, Hara H. Sci Rep; 2019 Mar 06; 9(1):3701. PubMed ID: 30842449 [Abstract] [Full Text] [Related]
8. Diminished motor neuron activity driven by abnormal astrocytic EAAT1 glutamate transporter activity in spinal muscular atrophy is not fully restored after lentiviral SMN delivery. Welby E, Ebert AD. Glia; 2023 May 06; 71(5):1311-1332. PubMed ID: 36655314 [Abstract] [Full Text] [Related]
9. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration. Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH. PLoS One; 2016 May 06; 11(12):e0167077. PubMed ID: 27907033 [Abstract] [Full Text] [Related]
10. Translational fidelity of intrathecal delivery of self-complementary AAV9-survival motor neuron 1 for spinal muscular atrophy. Passini MA, Bu J, Richards AM, Treleaven CM, Sullivan JA, O'Riordan CR, Scaria A, Kells AP, Samaranch L, San Sebastian W, Federici T, Fiandaca MS, Boulis NM, Bankiewicz KS, Shihabuddin LS, Cheng SH. Hum Gene Ther; 2014 Jul 06; 25(7):619-30. PubMed ID: 24617515 [Abstract] [Full Text] [Related]
11. AAV9-Stathmin1 gene delivery improves disease phenotype in an intermediate mouse model of spinal muscular atrophy. Villalón E, Kline RA, Smith CE, Lorson ZC, Osman EY, O'Day S, Murray LM, Lorson CL. Hum Mol Genet; 2019 Nov 15; 28(22):3742-3754. PubMed ID: 31363739 [Abstract] [Full Text] [Related]
12. AAV9-Mediated Expression of SMN Restricted to Neurons Does Not Rescue the Spinal Muscular Atrophy Phenotype in Mice. Besse A, Astord S, Marais T, Roda M, Giroux B, Lejeune FX, Relaix F, Smeriglio P, Barkats M, Biferi MG. Mol Ther; 2020 Aug 05; 28(8):1887-1901. PubMed ID: 32470325 [Abstract] [Full Text] [Related]
13. Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy. Lee AJ, Awano T, Park GH, Monani UR. PLoS One; 2012 Aug 05; 7(9):e46353. PubMed ID: 23029491 [Abstract] [Full Text] [Related]
14. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy. Deguise MO, De Repentigny Y, Tierney A, Beauvais A, Michaud J, Chehade L, Thabet M, Paul B, Reilly A, Gagnon S, Renaud JM, Kothary R. EBioMedicine; 2020 May 05; 55():102750. PubMed ID: 32339936 [Abstract] [Full Text] [Related]
15. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells. Lin X, Li JJ, Qian WJ, Zhang QJ, Wang ZF, Lu YQ, Dong EL, He J, Wang N, Ma LX, Chen WJ. Oncotarget; 2017 Jun 27; 8(26):42030-42042. PubMed ID: 28159932 [Abstract] [Full Text] [Related]
16. Hypothermia improves disease manifestations in SMA mice via SMN augmentation. Tsai LK, Chen CL, Tsai YC, Ting CH, Chien YH, Lee NC, Hwu WL. Hum Mol Genet; 2016 Feb 15; 25(4):631-41. PubMed ID: 26647309 [Abstract] [Full Text] [Related]
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18. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy. Riessland M, Ackermann B, Förster A, Jakubik M, Hauke J, Garbes L, Fritzsche I, Mende Y, Blumcke I, Hahnen E, Wirth B. Hum Mol Genet; 2010 Apr 15; 19(8):1492-506. PubMed ID: 20097677 [Abstract] [Full Text] [Related]
19. Proteomic assessment of a cell model of spinal muscular atrophy. Wu CY, Whye D, Glazewski L, Choe L, Kerr D, Lee KH, Mason RW, Wang W. BMC Neurosci; 2011 Mar 08; 12():25. PubMed ID: 21385431 [Abstract] [Full Text] [Related]
20. Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy. Hunter G, Powis RA, Jones RA, Groen EJ, Shorrock HK, Lane FM, Zheng Y, Sherman DL, Brophy PJ, Gillingwater TH. Hum Mol Genet; 2016 Jul 01; 25(13):2853-2861. PubMed ID: 27170316 [Abstract] [Full Text] [Related] Page: [Next] [New Search]