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391 related items for PubMed ID: 25918161

  • 1. PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells.
    Yuan Z, Guo W, Yang J, Li L, Wang M, Lei Y, Wan Y, Zhao X, Luo N, Cheng P, Liu X, Nie C, Peng Y, Tong A, Wei Y.
    J Biol Chem; 2015 Jun 12; 290(24):14927-44. PubMed ID: 25918161
    [Abstract] [Full Text] [Related]

  • 2. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
    Ray S, Shyam S, Fraizer GC, Almasan A.
    Mol Cancer Ther; 2007 Apr 12; 6(4):1368-78. PubMed ID: 17431115
    [Abstract] [Full Text] [Related]

  • 3. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR, Aau MY, Zhuang L, Yu Q.
    J Biol Chem; 2009 Feb 13; 284(7):4132-9. PubMed ID: 19060337
    [Abstract] [Full Text] [Related]

  • 4. hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells.
    Li L, Chen DB, Lin C, Cao K, Wan Y, Zhao XY, Nie CL, Yuan Z, Wei YQ.
    Apoptosis; 2013 Apr 13; 18(4):467-79. PubMed ID: 23322088
    [Abstract] [Full Text] [Related]

  • 5. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.
    Oncogene; 2011 Oct 13; 30(41):4261-74. PubMed ID: 21532626
    [Abstract] [Full Text] [Related]

  • 6. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.
    Pabla N, Huang S, Mi QS, Daniel R, Dong Z.
    J Biol Chem; 2008 Mar 07; 283(10):6572-83. PubMed ID: 18162465
    [Abstract] [Full Text] [Related]

  • 7. Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
    Kim JY, Choi HE, Lee HH, Shin JS, Shin DH, Choi JH, Lee YS, Lee KT.
    Oncol Rep; 2015 May 07; 33(5):2639-47. PubMed ID: 25812484
    [Abstract] [Full Text] [Related]

  • 8. NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway.
    Jayachandran G, Ueda K, Wang B, Roth JA, Ji L.
    PLoS One; 2010 Aug 05; 5(8):e11994. PubMed ID: 20700484
    [Abstract] [Full Text] [Related]

  • 9. Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
    Song X, Li L, Shi Q, Lehmler HJ, Fu J, Su C, Xia X, Song E, Song Y.
    Chem Res Toxicol; 2015 Nov 16; 28(11):2160-9. PubMed ID: 26451628
    [Abstract] [Full Text] [Related]

  • 10. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.
    Carcinogenesis; 2005 Nov 16; 26(11):1978-87. PubMed ID: 15975956
    [Abstract] [Full Text] [Related]

  • 11. p53 regulates cellular responses to environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide in human lung cancer cells.
    Xiao H, Singh SV.
    Cell Cycle; 2007 Jul 15; 6(14):1753-61. PubMed ID: 17630511
    [Abstract] [Full Text] [Related]

  • 12. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C, Tyagi A, Agarwal R.
    Mol Cancer Ther; 2006 Dec 15; 5(12):3294-302. PubMed ID: 17172433
    [Abstract] [Full Text] [Related]

  • 13. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.
    Cell Biol Int; 2009 Dec 15; 33(12):1237-44. PubMed ID: 19732843
    [Abstract] [Full Text] [Related]

  • 14. DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G2 arrest can occur independently of Chk1, Chk2 or MAPKAPK2.
    Zhang WH, Poh A, Fanous AA, Eastman A.
    Cell Cycle; 2008 Jun 01; 7(11):1668-77. PubMed ID: 18469532
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine.
    Sampath D, Shi Z, Plunkett W.
    Mol Pharmacol; 2002 Sep 01; 62(3):680-8. PubMed ID: 12181445
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells.
    Jirmanova L, Bulavin DV, Fornace AJ.
    Cell Cycle; 2005 Oct 01; 4(10):1428-34. PubMed ID: 16138010
    [Abstract] [Full Text] [Related]

  • 17. The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.
    Neumann J, Boerries M, Köhler R, Giaisi M, Krammer PH, Busch H, Li-Weber M.
    Int J Cancer; 2014 Apr 15; 134(8):1991-2002. PubMed ID: 24150948
    [Abstract] [Full Text] [Related]

  • 18. Topoisomerase inhibitor coralyne photosensitizes DNA, leading to elicitation of Chk2-dependent S-phase checkpoint and p53-independent apoptosis in cancer cells.
    Patro BS, Maity B, Chattopadhyay S.
    Antioxid Redox Signal; 2010 Apr 15; 12(8):945-60. PubMed ID: 19922265
    [Abstract] [Full Text] [Related]

  • 19. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R.
    J Cancer Res Clin Oncol; 2008 Feb 15; 134(2):245-53. PubMed ID: 17653574
    [Abstract] [Full Text] [Related]

  • 20. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
    Guo N, Faller DV, Vaziri C.
    Cell Growth Differ; 2002 Feb 15; 13(2):77-86. PubMed ID: 11864911
    [Abstract] [Full Text] [Related]

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