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291 related items for PubMed ID: 25934094

  • 1. Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
    Renga B, Bucci M, Cipriani S, Carino A, Monti MC, Zampella A, Gargiulo A, d'Emmanuele di Villa Bianca R, Distrutti E, Fiorucci S.
    Am J Physiol Heart Circ Physiol; 2015 Jul 01; 309(1):H114-26. PubMed ID: 25934094
    [Abstract] [Full Text] [Related]

  • 2. Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: role of gaseous mediators.
    Fiorucci S, Zampella A, Cirino G, Bucci M, Distrutti E.
    Am J Physiol Heart Circ Physiol; 2017 Jan 01; 312(1):H21-H32. PubMed ID: 27765751
    [Abstract] [Full Text] [Related]

  • 3. Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.
    Renga B, Cipriani S, Carino A, Simonetti M, Zampella A, Fiorucci S.
    PLoS One; 2015 Jan 01; 10(11):e0141082. PubMed ID: 26539823
    [Abstract] [Full Text] [Related]

  • 4. Targeting the transsulfuration-H2S pathway by FXR and GPBAR1 ligands in the treatment of portal hypertension.
    Fiorucci S, Distrutti E.
    Pharmacol Res; 2016 Sep 01; 111():749-756. PubMed ID: 27475883
    [Abstract] [Full Text] [Related]

  • 5. Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation.
    Renga B, Mencarelli A, Migliorati M, Distrutti E, Fiorucci S.
    World J Gastroenterol; 2009 May 07; 15(17):2097-108. PubMed ID: 19418582
    [Abstract] [Full Text] [Related]

  • 6. Endogenous hydrogen sulfide-mediated MAPK inhibition preserves endothelial function through TXNIP signaling.
    Tian D, Dong J, Jin S, Teng X, Wu Y.
    Free Radic Biol Med; 2017 Sep 07; 110():291-299. PubMed ID: 28669627
    [Abstract] [Full Text] [Related]

  • 7. Dysregulation of cystathionine γ-lyase (CSE)/hydrogen sulfide pathway contributes to ox-LDL-induced inflammation in macrophage.
    Wang XH, Wang F, You SJ, Cao YJ, Cao LD, Han Q, Liu CF, Hu LF.
    Cell Signal; 2013 Nov 07; 25(11):2255-62. PubMed ID: 23872072
    [Abstract] [Full Text] [Related]

  • 8. Cystathionine γ-Lyase Modulates Flow-Dependent Vascular Remodeling.
    Yuan S, Yurdagul A, Peretik JM, Alfaidi M, Al Yafeai Z, Pardue S, Kevil CG, Orr AW.
    Arterioscler Thromb Vasc Biol; 2018 Sep 07; 38(9):2126-2136. PubMed ID: 30002061
    [Abstract] [Full Text] [Related]

  • 9. NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to intermittent hypoxia.
    Gonzalez Bosc LV, Osmond JM, Giermakowska WK, Pace CE, Riggs JL, Jackson-Weaver O, Kanagy NL.
    Am J Physiol Heart Circ Physiol; 2017 Apr 01; 312(4):H791-H799. PubMed ID: 28130342
    [Abstract] [Full Text] [Related]

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  • 11. Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.
    Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I.
    Circulation; 2019 Jan 02; 139(1):101-114. PubMed ID: 29970364
    [Abstract] [Full Text] [Related]

  • 12. CD4+ T-Cell Endogenous Cystathionine γ Lyase-Hydrogen Sulfide Attenuates Hypertension by Sulfhydrating Liver Kinase B1 to Promote T Regulatory Cell Differentiation and Proliferation.
    Cui C, Fan J, Zeng Q, Cai J, Chen Y, Chen Z, Wang W, Li SY, Cui Q, Yang J, Tang C, Xu G, Cai J, Geng B.
    Circulation; 2020 Nov 03; 142(18):1752-1769. PubMed ID: 32900241
    [Abstract] [Full Text] [Related]

  • 13. MPST but not CSE is the primary regulator of hydrogen sulfide production and function in the coronary artery.
    Kuo MM, Kim DH, Jandu S, Bergman Y, Tan S, Wang H, Pandey DR, Abraham TP, Shoukas AA, Berkowitz DE, Santhanam L.
    Am J Physiol Heart Circ Physiol; 2016 Jan 01; 310(1):H71-9. PubMed ID: 26519030
    [Abstract] [Full Text] [Related]

  • 14. 17β-Estradiol nongenomically induces vascular endothelial H2S release by promoting phosphorylation of cystathionine γ-lyase.
    Xu X, Yan Q, Liu X, Li P, Li X, Chen Y, Simoncini T, Liu J, Zhu D, Fu X.
    J Biol Chem; 2019 Oct 25; 294(43):15577-15592. PubMed ID: 31439665
    [Abstract] [Full Text] [Related]

  • 15. Angiotensin II downregulates vascular endothelial cell hydrogen sulfide production by enhancing cystathionine γ-lyase degradation through ROS-activated ubiquitination pathway.
    Bai L, Qi Y, Chen S, Wang J, Tang C, Du J, Jin H, Huang Y.
    Biochem Biophys Res Commun; 2019 Jun 30; 514(3):907-912. PubMed ID: 31084929
    [Abstract] [Full Text] [Related]

  • 16. Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment.
    Kolluru GK, Bir SC, Yuan S, Shen X, Pardue S, Wang R, Kevil CG.
    Cardiovasc Res; 2015 Sep 01; 107(4):590-600. PubMed ID: 26194202
    [Abstract] [Full Text] [Related]

  • 17. The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
    Carino A, Marchianò S, Biagioli M, Scarpelli P, Bordoni M, Di Giorgio C, Roselli R, Fiorucci C, Monti MC, Distrutti E, Zampella A, Fiorucci S.
    FASEB J; 2021 Jan 01; 35(1):e21271. PubMed ID: 33368684
    [Abstract] [Full Text] [Related]

  • 18. Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6.
    Leucker TM, Nomura Y, Kim JH, Bhatta A, Wang V, Wecker A, Jandu S, Santhanam L, Berkowitz D, Romer L, Pandey D.
    Am J Physiol Heart Circ Physiol; 2017 Apr 01; 312(4):H711-H720. PubMed ID: 28188215
    [Abstract] [Full Text] [Related]

  • 19. Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury.
    Xia H, Li Z, Sharp TE, Polhemus DJ, Carnal J, Moles KH, Tao YX, Elrod J, Pfeilschifter J, Beck KF, Lefer DJ.
    J Am Heart Assoc; 2020 Oct 20; 9(19):e017544. PubMed ID: 32990120
    [Abstract] [Full Text] [Related]

  • 20. SKF38393 prevents high glucose (HG)-induced endothelial dysfunction by inhibiting the effects of HG on cystathionine γ-lyase/hydrogen sulfide activity and via a RhoA/ROCK1 pathway.
    Chang GQ, Bai SZ, Sun FQ, Wu R, Wei C, Wen X, Xi YX, Hao JH, Zaid A, Li HZ.
    Front Biosci (Landmark Ed); 2022 Feb 11; 27(2):49. PubMed ID: 35226992
    [Abstract] [Full Text] [Related]

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