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Journal Abstract Search

377 related items for PubMed ID: 25937236

  • 1. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
    Wang F, Yang Z, Liu Y, Ma L, Wu Y, He L, Shao M, Yu K, Wu W, Pu Y, Nie C, Chen L.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3337-50. PubMed ID: 25937236
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
    Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Bertolasi V, Cancellieri M, Brancale A, Hamel E, Castagliuolo I, Consolaro F, Porcù E, Basso G, Viola G.
    J Med Chem; 2014 Aug 14; 57(15):6795-808. PubMed ID: 25025853
    [Abstract] [Full Text] [Related]

  • 3. Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes.
    Lee HY, Chang CY, Lai MJ, Chuang HY, Kuo CC, Chang CY, Chang JY, Liou JP.
    Bioorg Med Chem; 2015 Aug 01; 23(15):4230-4236. PubMed ID: 26160020
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of novel millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Yang Z, Wu W, Wang J, Liu L, Li L, Yang J, Wang G, Cao D, Zhang R, Tang M, Wen J, Zhu J, Xiang W, Wang F, Ma L, Xiang M, You J, Chen L.
    J Med Chem; 2014 Oct 09; 57(19):7977-89. PubMed ID: 25208345
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E.
    J Med Chem; 2007 May 03; 50(9):2273-7. PubMed ID: 17419607
    [Abstract] [Full Text] [Related]

  • 6. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
    Lee HY, Chang JY, Nien CY, Kuo CC, Shih KH, Wu CH, Chang CY, Lai WY, Liou JP.
    J Med Chem; 2011 Dec 22; 54(24):8517-25. PubMed ID: 22060033
    [Abstract] [Full Text] [Related]

  • 7. SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.
    Yan W, Yang T, Yang J, Wang T, Yu Y, Wang Y, Chen Q, Bai P, Li D, Ye H, Qiu Q, Zhou Y, Hu Y, Yang S, Wei Y, Li W, Chen L.
    Cell Physiol Biochem; 2018 Dec 22; 47(2):489-504. PubMed ID: 29794416
    [Abstract] [Full Text] [Related]

  • 8. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
    Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N.
    J Med Chem; 2016 Sep 22; 59(18):8422-40. PubMed ID: 27538123
    [Abstract] [Full Text] [Related]

  • 11. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 12. Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
    Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Porcù E, Basso G, Viola G.
    J Med Chem; 2012 Jun 14; 55(11):5433-45. PubMed ID: 22578111
    [Abstract] [Full Text] [Related]

  • 13. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
    Romagnoli R, Oliva P, Salvador MK, Manfredini S, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2021 Mar 15; 214():113229. PubMed ID: 33550186
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.
    Li W, Sun H, Xu F, Shuai W, Liu J, Xu S, Yao H, Ma C, Zhu Z, Xu J.
    Bioorg Chem; 2019 Apr 15; 85():49-59. PubMed ID: 30599412
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A, Balakrishna M, Nayak VL, Shaik TB, Faazil S, Nimbarte VD.
    ChemMedChem; 2014 Dec 15; 9(12):2766-80. PubMed ID: 25313981
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents.
    Hamze A, Giraud A, Messaoudi S, Provot O, Peyrat JF, Bignon J, Liu JM, Wdzieczak-Bakala J, Thoret S, Dubois J, Brion JD, Alami M.
    ChemMedChem; 2009 Nov 15; 4(11):1912-24. PubMed ID: 19790205
    [Abstract] [Full Text] [Related]

  • 17. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 15; 7(4):680-93. PubMed ID: 22311585
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and structure-activity relationships of N-methyl-5,6,7-trimethoxylindoles as novel antimitotic and vascular disrupting agents.
    Zhao DG, Chen J, Du YR, Ma YY, Chen YX, Gao K, Hu BR.
    J Med Chem; 2013 Feb 28; 56(4):1467-77. PubMed ID: 23360369
    [Abstract] [Full Text] [Related]

  • 19. BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities.
    Hu CB, Chen CP, Yeh TK, Song JS, Chang CY, Chuu JJ, Tung FF, Ho PY, Chen TW, Lin CH, Wang MH, Chang KY, Huang CL, Lin HL, Li WT, Hwang DR, Chern JH, Hwang LL, Chang JY, Chao YS, Chen CT.
    Cancer Sci; 2011 Jan 28; 102(1):182-91. PubMed ID: 21040217
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors.
    Shuai W, Li X, Li W, Xu F, Lu L, Yao H, Yang L, Zhu H, Xu S, Zhu Z, Xu J.
    Eur J Med Chem; 2020 Jul 01; 197():112308. PubMed ID: 32339853
    [Abstract] [Full Text] [Related]

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