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566 related items for PubMed ID: 25944913
1. Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells. Tan B, Dong S, Shepard RL, Kays L, Roth KD, Geeganage S, Kuo MS, Zhao G. J Biol Chem; 2015 Jun 19; 290(25):15812-15824. PubMed ID: 25944913 [Abstract] [Full Text] [Related]
2. Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. Tan B, Young DA, Lu ZH, Wang T, Meier TI, Shepard RL, Roth K, Zhai Y, Huss K, Kuo MS, Gillig J, Parthasarathy S, Burkholder TP, Smith MC, Geeganage S, Zhao G. J Biol Chem; 2013 Feb 01; 288(5):3500-11. PubMed ID: 23239881 [Abstract] [Full Text] [Related]
3. CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. Grozio A, Sociali G, Sturla L, Caffa I, Soncini D, Salis A, Raffaelli N, De Flora A, Nencioni A, Bruzzone S. J Biol Chem; 2013 Sep 06; 288(36):25938-25949. PubMed ID: 23880765 [Abstract] [Full Text] [Related]
4. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer. Ju HQ, Zhuang ZN, Li H, Tian T, Lu YX, Fan XQ, Zhou HJ, Mo HY, Sheng H, Chiao PJ, Xu RH. Cancer Lett; 2016 Aug 28; 379(1):1-11. PubMed ID: 27233476 [Abstract] [Full Text] [Related]
5. EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells. Mutz CN, Schwentner R, Aryee DNT, Bouchard EDJ, Mejia EM, Hatch GM, Kauer MO, Katschnig AM, Ban J, Garten A, Alonso J, Banerji V, Kovar H. Oncotarget; 2017 Apr 11; 8(15):24679-24693. PubMed ID: 28160567 [Abstract] [Full Text] [Related]
6. NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms. Zhang XQ, Lu JT, Jiang WX, Lu YB, Wu M, Wei EQ, Zhang WP, Tang C. Neuroscience; 2015 Apr 16; 291():230-40. PubMed ID: 25684751 [Abstract] [Full Text] [Related]
7. Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway. Wang LF, Wang XN, Huang CC, Hu L, Xiao YF, Guan XH, Qian YS, Deng KY, Xin HB. Lipids Health Dis; 2017 Apr 27; 16(1):82. PubMed ID: 28449683 [Abstract] [Full Text] [Related]
9. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells. Schuster S, Penke M, Gorski T, Gebhardt R, Weiss TS, Kiess W, Garten A. Biochem Biophys Res Commun; 2015 Mar 06; 458(2):334-40. PubMed ID: 25656579 [Abstract] [Full Text] [Related]
10. Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition. Cea M, Cagnetta A, Fulciniti M, Tai YT, Hideshima T, Chauhan D, Roccaro A, Sacco A, Calimeri T, Cottini F, Jakubikova J, Kong SY, Patrone F, Nencioni A, Gobbi M, Richardson P, Munshi N, Anderson KC. Blood; 2012 Oct 25; 120(17):3519-29. PubMed ID: 22955917 [Abstract] [Full Text] [Related]
12. Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level. Ye C, Qi L, Li X, Wang J, Yu J, Zhou B, Guo C, Chen J, Zheng S. Cell Commun Signal; 2020 Jan 31; 18(1):16. PubMed ID: 32005247 [Abstract] [Full Text] [Related]
13. Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD+-Sirt1 signaling. Pi C, Yang Y, Sun Y, Wang H, Sun H, Ma M, Lin L, Shi Y, Li Y, Li Y, He X. Aging (Albany NY); 2019 Jun 07; 11(11):3505-3522. PubMed ID: 31175267 [Abstract] [Full Text] [Related]
14. The sodium phosphate cotransporter family and nicotinamide phosphoribosyltransferase contribute to the daily oscillation of plasma inorganic phosphate concentration. Miyagawa A, Tatsumi S, Takahama W, Fujii O, Nagamoto K, Kinoshita E, Nomura K, Ikuta K, Fujii T, Hanazaki A, Kaneko I, Segawa H, Miyamoto KI. Kidney Int; 2018 May 07; 93(5):1073-1085. PubMed ID: 29398136 [Abstract] [Full Text] [Related]
15. NAMPT suppresses glucose deprivation-induced oxidative stress by increasing NADPH levels in breast cancer. Hong SM, Park CW, Kim SW, Nam YJ, Yu JH, Shin JH, Yun CH, Im SH, Kim KT, Sung YC, Choi KY. Oncogene; 2016 Jul 07; 35(27):3544-54. PubMed ID: 26568303 [Abstract] [Full Text] [Related]
17. Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer. Kudo K, Nomura M, Sakamoto Y, Ito S, Morita M, Kawai M, Yamashita Y, Ito K, Yamada H, Shima H, Yaegashi N, Tanuma N. FEBS Lett; 2020 May 07; 594(9):1379-1388. PubMed ID: 31950503 [Abstract] [Full Text] [Related]
18. Genomic and tumor biological aspects of the anticancer nicotinamide phosphoribosyltransferase inhibitor FK866 in resistant human colorectal cancer cells. Ogino Y, Sato A, Uchiumi F, Tanuma SI. Genomics; 2019 Dec 07; 111(6):1889-1895. PubMed ID: 30582964 [Abstract] [Full Text] [Related]
19. Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer. Pan JH, Zhou H, Zhu SB, Huang JL, Zhao XX, Ding H, Qin L, Pan YL. J Cell Physiol; 2019 Apr 07; 234(4):4385-4395. PubMed ID: 30191976 [Abstract] [Full Text] [Related]