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Journal Abstract Search

345 related items for PubMed ID: 25957661

  • 1. Synthesis of aryl dihydrothiazol acyl shikonin ester derivatives as anticancer agents through microtubule stabilization.
    Lin HY, Li ZK, Bai LF, Baloch SK, Wang F, Qiu HY, Wang X, Qi JL, Yang RW, Wang XM, Yang YH.
    Biochem Pharmacol; 2015 Jul 15; 96(2):93-106. PubMed ID: 25957661
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.
    Sun WX, Han HW, Yang MK, Wen ZL, Wang YS, Fu JY, Lu YT, Wang MY, Bao JX, Lu GH, Qi JL, Wang XM, Lin HY, Yang YH.
    Bioorg Med Chem; 2019 Dec 01; 27(23):115153. PubMed ID: 31648877
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of heterocyclic carboxylic acyl shikonin derivatives.
    Wang XM, Lin HY, Kong WY, Guo J, Shi J, Huang SC, Qi JL, Yang RW, Gu HW, Yang YH.
    Chem Biol Drug Des; 2014 Mar 01; 83(3):334-43. PubMed ID: 24118825
    [Abstract] [Full Text] [Related]

  • 4. A potent anticancer agent of shikonin derivative targeting tubulin.
    Baloch SK, Ma L, Xu GH, Bai LF, Zhao H, Tang CY, Pang YJ, Yang RW, Wang XM, Lu GH, Yang YH.
    Chirality; 2015 Mar 01; 27(3):274-80. PubMed ID: 25663187
    [Abstract] [Full Text] [Related]

  • 5. Design, Synthesis, and Biological Evaluation of Chalcone-Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization.
    Qiu HY, Wang F, Wang X, Sun WX, Qi JL, Pang YJ, Yang RW, Lu GH, Wang XM, Yang YH.
    ChemMedChem; 2017 Mar 07; 12(5):399-406. PubMed ID: 28211616
    [Abstract] [Full Text] [Related]

  • 6. Design and characterization of α-lipoic acyl shikonin ester twin drugs as tubulin and PDK1 dual inhibitors.
    Lin HY, Han HW, Sun WX, Yang YS, Tang CY, Lu GH, Qi JL, Wang XM, Yang YH.
    Eur J Med Chem; 2018 Jan 20; 144():137-150. PubMed ID: 29268130
    [Abstract] [Full Text] [Related]

  • 7. Novel shikonin derivatives targeting tubulin as anticancer agents.
    Guo J, Chen XF, Liu J, Lin HY, Han HW, Liu HC, Huang SC, Shahla BK, Kulek A, Qi JL, Wang XM, Ling LJ, Yang YH.
    Chem Biol Drug Des; 2014 Nov 20; 84(5):603-15. PubMed ID: 24797889
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
    Shao YY, Yin Y, Lian BP, Leng JF, Xia YZ, Kong LY.
    Eur J Med Chem; 2020 Mar 15; 190():112105. PubMed ID: 32035399
    [Abstract] [Full Text] [Related]

  • 9. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 10. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A, Balakrishna M, Nayak VL, Shaik TB, Faazil S, Nimbarte VD.
    ChemMedChem; 2014 Dec 01; 9(12):2766-80. PubMed ID: 25313981
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of novel benzo[c]acridine-diones as potential anticancer agents and tubulin polymerization inhibitors.
    Behbahani FS, Tabeshpour J, Mirzaei S, Golmakaniyoon S, Tayarani-Najaran Z, Ghasemi A, Ghodsi R.
    Arch Pharm (Weinheim); 2019 Jun 13; 352(6):e1800307. PubMed ID: 31012156
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
    Padmaja P, Koteswara Rao G, Indrasena A, Subba Reddy BV, Patel N, Shaik AB, Reddy N, Dubey PK, Bhadra MP.
    Org Biomol Chem; 2015 Feb 07; 13(5):1404-14. PubMed ID: 25467166
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G, Liu W, Fan M, He M, Li Y, Peng Z.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):1694-1702. PubMed ID: 34309466
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 01; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 18. Biochemical characterization and molecular dynamic simulation of β-sitosterol as a tubulin-binding anticancer agent.
    Mahaddalkar T, Suri C, Naik PK, Lopus M.
    Eur J Pharmacol; 2015 Aug 05; 760():154-62. PubMed ID: 25912799
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, cytotoxic evaluation and molecular docking study of 2-alkylthio-4-(2,3,4-trimethoxyphenyl)-5-aryl-thiazoles as tubulin polymerization inhibitors.
    Salehi M, Amini M, Ostad SN, Riazi GH, Assadieskandar A, Shafiei B, Shafiee A.
    Bioorg Med Chem; 2013 Dec 15; 21(24):7648-54. PubMed ID: 24238904
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
    Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):147-52. PubMed ID: 23200248
    [Abstract] [Full Text] [Related]

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