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Journal Abstract Search

402 related items for PubMed ID: 25957813

  • 1. Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit.
    Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA.
    Neuropharmacology; 2015 Dec; 99():273-84. PubMed ID: 25957813
    [Abstract] [Full Text] [Related]

  • 2. Rare human nicotinic acetylcholine receptor α4 subunit (CHRNA4) variants affect expression and function of high-affinity nicotinic acetylcholine receptors.
    McClure-Begley TD, Papke RL, Stone KL, Stokes C, Levy AD, Gelernter J, Xie P, Lindstrom J, Picciotto MR.
    J Pharmacol Exp Ther; 2014 Mar; 348(3):410-20. PubMed ID: 24385388
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  • 3. Contribution of position alpha4S336 on functional expression and up-regulation of alpha4beta2 neuronal nicotinic receptors.
    López-Hernández GY, Biaggi-Labiosa NM, Torres-Cintrón A, Ortiz-Acevedo A, Lasalde-Dominicci JA.
    Cell Mol Neurobiol; 2009 Feb; 29(1):41-53. PubMed ID: 18818999
    [Abstract] [Full Text] [Related]

  • 4. Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site.
    Shimomura M, Yokota M, Ihara M, Akamatsu M, Sattelle DB, Matsuda K.
    Mol Pharmacol; 2006 Oct; 70(4):1255-63. PubMed ID: 16868180
    [Abstract] [Full Text] [Related]

  • 5. Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors.
    Olsen JA, Ahring PK, Kastrup JS, Gajhede M, Balle T.
    J Biol Chem; 2014 Sep 05; 289(36):24911-21. PubMed ID: 24982426
    [Abstract] [Full Text] [Related]

  • 6. Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2* receptor expression and clustering.
    Zambrano CA, Escobar D, Ramos-Santiago T, Bollinger I, Stitzel J.
    Biochem Pharmacol; 2019 Jan 05; 159():64-73. PubMed ID: 30414940
    [Abstract] [Full Text] [Related]

  • 7. Roles of nicotinic acetylcholine receptor β subunit cytoplasmic loops in acute desensitization and single-channel features.
    Liu Q, Kuo YP, Shen J, Lukas RJ, Wu J.
    Neuroscience; 2015 Mar 19; 289():315-23. PubMed ID: 25536046
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  • 9. Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.
    Lucero LM, Weltzin MM, Eaton JB, Cooper JF, Lindstrom JM, Lukas RJ, Whiteaker P.
    J Biol Chem; 2016 Jan 29; 291(5):2444-59. PubMed ID: 26644472
    [Abstract] [Full Text] [Related]

  • 10. Roles for nicotinic acetylcholine receptor subunit large cytoplasmic loop sequences in receptor expression and function.
    Kuo YP, Xu L, Eaton JB, Zhao L, Wu J, Lukas RJ.
    J Pharmacol Exp Ther; 2005 Jul 29; 314(1):455-66. PubMed ID: 15833891
    [Abstract] [Full Text] [Related]

  • 11. Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC.
    Norleans J, Wang J, Kuryatov A, Leffler A, Doebelin C, Kamenecka TM, Lindstrom J.
    J Biol Chem; 2019 Aug 09; 294(32):12132-12145. PubMed ID: 31221718
    [Abstract] [Full Text] [Related]

  • 12. Cyclic AMP-dependent protein kinase (PKA) and protein kinase C phosphorylate sites in the amino acid sequence corresponding to the M3/M4 cytoplasmic domain of alpha4 neuronal nicotinic receptor subunits.
    Wecker L, Guo X, Rycerz AM, Edwards SC.
    J Neurochem; 2001 Feb 09; 76(3):711-20. PubMed ID: 11158241
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  • 15. Identification of three cAMP-dependent protein kinase (PKA) phosphorylation sites within the major intracellular domain of neuronal nicotinic receptor alpha4 subunits.
    Guo X, Wecker L.
    J Neurochem; 2002 Jul 09; 82(2):439-47. PubMed ID: 12124445
    [Abstract] [Full Text] [Related]

  • 16. Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy.
    Weltzin MM, Lindstrom JM, Lukas RJ, Whiteaker P.
    Neuropharmacology; 2016 Mar 09; 102():158-73. PubMed ID: 26561946
    [Abstract] [Full Text] [Related]

  • 17. Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms.
    Weltzin MM, George AA, Lukas RJ, Whiteaker P.
    PLoS One; 2019 Mar 09; 14(3):e0213143. PubMed ID: 30845161
    [Abstract] [Full Text] [Related]

  • 18. An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors.
    Wang J, Kuryatov A, Sriram A, Jin Z, Kamenecka TM, Kenny PJ, Lindstrom J.
    J Biol Chem; 2015 May 29; 290(22):13907-18. PubMed ID: 25869137
    [Abstract] [Full Text] [Related]

  • 19. The additional ACh binding site at the α4(+)/α4(-) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization.
    Benallegue N, Mazzaferro S, Alcaino C, Bermudez I.
    Br J Pharmacol; 2013 Sep 29; 170(2):304-16. PubMed ID: 23742319
    [Abstract] [Full Text] [Related]

  • 20. Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm.
    Shao XM, Tan W, Xiu J, Puskar N, Fonck C, Lester HA, Feldman JL.
    J Neurosci; 2008 Jan 09; 28(2):519-28. PubMed ID: 18184794
    [Abstract] [Full Text] [Related]

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