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352 related items for PubMed ID: 25960253

  • 1. Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.
    Janočková J, Plšíková J, Kašpárková J, Brabec V, Jendželovský R, Mikeš J, Kovaľ J, Hamuľaková S, Fedoročko P, Kuča K, Kožurková M.
    Eur J Pharm Sci; 2015 Aug 30; 76():192-202. PubMed ID: 25960253
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  • 4. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
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  • 5. Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.
    Yao BL, Mai YW, Chen SB, Xie HT, Yao PF, Ou TM, Tan JH, Wang HG, Li D, Huang SL, Gu LQ, Huang ZS.
    Eur J Med Chem; 2015 Mar 06; 92():540-53. PubMed ID: 25599951
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  • 6. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Zhang W, Zhang B, Zhang W, Yang T, Wang N, Gao C, Tan C, Liu H, Jiang Y.
    Eur J Med Chem; 2016 Jun 30; 116():59-70. PubMed ID: 27060757
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  • 7. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S, Vandenberghe I, Robin M, Annereau JP, Créancier L, Pique V, Galy JP, Kruczynski A, Barret JM, Bailly C.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1863-72. PubMed ID: 17391647
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  • 8. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT, Woo H, Jeong HM, Khadka DB, Yang SH, Zhao C, Jin Y, Lee ES, Youl Lee K, Kwon Y, Cho WJ.
    Eur J Med Chem; 2014 Jul 23; 82():181-94. PubMed ID: 24904965
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  • 9. New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds.
    Salem OM, Vilková M, Janočková J, Jendželovský R, Fedoročko P, Žilecká E, Kašpárková J, Brabec V, Imrich J, Kožurková M.
    Int J Biol Macromol; 2016 May 23; 86():690-700. PubMed ID: 26861825
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  • 11. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L, Marzaro G, Ferrarese A, Gia O, Chilin A.
    Eur J Med Chem; 2014 Apr 22; 77():103-9. PubMed ID: 24631729
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  • 12. Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Li D, Yuan Z, Chen S, Zhang C, Song L, Gao C, Chen Y, Tan C, Jiang Y.
    Bioorg Med Chem; 2017 Jul 01; 25(13):3437-3446. PubMed ID: 28511910
    [Abstract] [Full Text] [Related]

  • 13. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    Khadka DB, Tran GH, Shin S, Nguyen HT, Cao HT, Zhao C, Jin Y, Van HT, Chau MV, Kwon Y, Le TN, Cho WJ.
    Eur J Med Chem; 2015 Oct 20; 103():69-79. PubMed ID: 26334499
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.
    Deane FM, O'Sullivan EC, Maguire AR, Gilbert J, Sakoff JA, McCluskey A, McCarthy FO.
    Org Biomol Chem; 2013 Feb 28; 11(8):1334-44. PubMed ID: 23314103
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  • 15. Synthesis and biological activities of topopyrones.
    Zaleski PA, Maini R, Leiris SJ, Elban MA, Hecht SM.
    J Nat Prod; 2012 Apr 27; 75(4):577-85. PubMed ID: 22462811
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  • 16. Synthesis, DNA binding and topoisomerase I inhibition activity of thiazacridine and imidazacridine derivatives.
    Lafayette EA, Vitalino de Almeida SM, Pitta MG, Carneiro Beltrão EI, da Silva TG, Olímpio de Moura R, Pitta Ida R, de Carvalho LB, de Lima Mdo C.
    Molecules; 2013 Dec 06; 18(12):15035-50. PubMed ID: 24322489
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  • 17. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
    Park S, Thapa Magar TB, Kadayat TM, Lee HJ, Bist G, Shrestha A, Lee ES, Kwon Y.
    Eur J Med Chem; 2017 Feb 15; 127():318-333. PubMed ID: 28068603
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  • 18. 3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents.
    Plsikova J, Janovec L, Koval J, Ungvarsky J, Mikes J, Jendzelovsky R, Fedorocko P, Imrich J, Kristian P, Kasparkova J, Brabec V, Kozurkova M.
    Eur J Med Chem; 2012 Nov 15; 57():283-95. PubMed ID: 23072739
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  • 19. Synthesis of benzo-annulated tryptanthrins and their biological properties.
    Liang JL, Park SE, Kwon Y, Jahng Y.
    Bioorg Med Chem; 2012 Aug 15; 20(16):4962-7. PubMed ID: 22819942
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  • 20. Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study.
    Krochtová K, Halečková A, Janovec L, Blizniaková M, Kušnírová K, Kožurková M.
    Molecules; 2023 Jan 30; 28(3):. PubMed ID: 36770975
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