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Journal Abstract Search

352 related items for PubMed ID: 25960253

  • 21. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM, Song C, Shin S, Magar TB, Bist G, Shrestha A, Thapa P, Na Y, Kwon Y, Lee ES.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3499-512. PubMed ID: 26022080
    [Abstract] [Full Text] [Related]

  • 22. Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs.
    Salerno S, Da Settimo F, Taliani S, Simorini F, La Motta C, Fornaciari G, Marini AM.
    Curr Med Chem; 2010 Jul 01; 17(35):4270-90. PubMed ID: 20939813
    [Abstract] [Full Text] [Related]

  • 23. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R, Jun KY, Kadayat TM, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES.
    Eur J Med Chem; 2016 May 04; 113():228-45. PubMed ID: 26945111
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  • 24. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    Abdel-Aziz M, Park SE, Abuo-Rahma Gel-D, Sayed MA, Kwon Y.
    Eur J Med Chem; 2013 Nov 04; 69():427-38. PubMed ID: 24090914
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  • 25. Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa U, Thapa P, Karki R, Yun M, Choi JH, Jahng Y, Lee E, Jeon KH, Na Y, Ha EM, Cho WJ, Kwon Y, Lee ES.
    Eur J Med Chem; 2011 Aug 04; 46(8):3201-9. PubMed ID: 21601964
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  • 26. 3-[(E)-(acridin-9'-ylmethylidene)amino]-1-substituted thioureas and their biological activity.
    Bečka M, Vilková M, Salem O, Kašpárková J, Brabec V, Kožurková M.
    Spectrochim Acta A Mol Biomol Spectrosc; 2017 Jun 05; 180():234-241. PubMed ID: 28315620
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  • 27. Interaction of cholinesterase modulators with DNA and their cytotoxic activity.
    Janockova J, Gulasova Z, Plsikova J, Musilek K, Kuca K, Mikes J, Culka L, Fedorocko P, Kozurkova M.
    Int J Biol Macromol; 2014 Mar 05; 64():53-62. PubMed ID: 24296409
    [Abstract] [Full Text] [Related]

  • 28. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
    Li PH, Jiang H, Zhang WJ, Li YL, Zhao MC, Zhou W, Zhang LY, Tang YD, Dong CZ, Huang ZS, Chen HX, Du ZY.
    Eur J Med Chem; 2018 Feb 10; 145():498-510. PubMed ID: 29335211
    [Abstract] [Full Text] [Related]

  • 29. Design and synthesis of heterobimetallic topoisomerase I and II inhibitor complexes: in vitro DNA binding, interaction with 5'-GMP and 5'-TMP and cleavage studies.
    Arjmand F, Muddassir M.
    J Photochem Photobiol B; 2010 Oct 05; 101(1):37-46. PubMed ID: 20638859
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  • 30. Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
    Gouveia RG, Ribeiro AG, Segundo MÂSP, de Oliveira JF, de Lima MDCA, de Lima Souza TRC, de Almeida SMV, de Moura RO.
    Bioorg Med Chem; 2018 Dec 01; 26(22):5911-5921. PubMed ID: 30420325
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  • 31. Potentiation of the antitumor effect of 11-keto-β-boswellic acid by its 3-α-hexanoyloxy derivative.
    Chashoo G, Singh SK, Mondhe DM, Sharma PR, Andotra SS, Shah BA, Taneja SC, Saxena AK.
    Eur J Pharmacol; 2011 Oct 15; 668(3):390-400. PubMed ID: 21821018
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  • 32. Assessment of DNA-binding affinity of cholinesterase reactivators and electrophoretic determination of their effect on topoisomerase I and II activity.
    Janockova J, Zilecka E, Kasparkova J, Brabec V, Soukup O, Kuca K, Kozurkova M.
    Mol Biosyst; 2016 Aug 16; 12(9):2910-20. PubMed ID: 27412811
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  • 33. Novel indolizino[8,7-b]indole hybrids as anti-small cell lung cancer agents: Regioselective modulation of topoisomerase II inhibitory and DNA crosslinking activities.
    Chang SM, Christian W, Wu MH, Chen TL, Lin YW, Suen CS, Pidugu HB, Detroja D, Shah A, Hwang MJ, Su TL, Lee TC.
    Eur J Med Chem; 2017 Feb 15; 127():235-249. PubMed ID: 28064078
    [Abstract] [Full Text] [Related]

  • 34. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P, Kadayat TM, Park S, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES.
    Bioorg Chem; 2016 Jun 15; 66():145-59. PubMed ID: 27174797
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  • 35. 3-chloromethylene-6-fluorothiochroman-4-one, A novel DNA Topoisomerase poison.
    Wang Y, Chen J, Shen R, Yang C, Ma Z, Liu Y.
    Pak J Pharm Sci; 2016 Nov 15; 29(6 Suppl):2377-2383. PubMed ID: 28167481
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  • 36. New spiro-acridines: DNA interaction, antiproliferative activity and inhibition of human DNA topoisomerases.
    Almeida SM, Lafayette EA, Silva WL, Lima Serafim V, Menezes TM, Neves JL, Ruiz AL, Carvalho JE, Moura RO, Beltrão EI, Carvalho Júnior LB, Lima MD.
    Int J Biol Macromol; 2016 Nov 15; 92():467-475. PubMed ID: 27435006
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  • 37. A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase I & II inhibition.
    Chashoo G, Singh SK, Sharma PR, Mondhe DM, Hamid A, Saxena A, Andotra SS, Shah BA, Qazi NA, Taneja SC, Saxena AK.
    Chem Biol Interact; 2011 Jan 15; 189(1-2):60-71. PubMed ID: 21056033
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  • 38. Topoisomerase I/II inhibition by a novel naphthoquinone containing a modified anthracycline ring system.
    Kennedy S, DiCesare JC, Sheaff RJ.
    Biochem Biophys Res Commun; 2011 Apr 29; 408(1):94-8. PubMed ID: 21458415
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  • 39. Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
    Konkoľová E, Hudáčová M, Hamuľaková S, Jendželovský R, Vargová J, Ševc J, Fedoročko P, Kožurková M.
    Molecules; 2021 Feb 20; 26(4):. PubMed ID: 33672694
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  • 40. Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
    Christodoulou MS, Calogero F, Baumann M, García-Argáez AN, Pieraccini S, Sironi M, Dapiaggi F, Bucci R, Broggini G, Gazzola S, Liekens S, Silvani A, Lahtela-Kakkonen M, Martinet N, Nonell-Canals A, Santamaría-Navarro E, Baxendale IR, Dalla Via L, Passarella D.
    Eur J Med Chem; 2015 Mar 06; 92():766-75. PubMed ID: 25626146
    [Abstract] [Full Text] [Related]

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