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Journal Abstract Search


129 related items for PubMed ID: 2597180

  • 1. Catalytic effect of serum albumin on the o-rearrangement of N-sulfooxy-2-acetylaminofluorene, a potential hepatocarcinogen in the rat, to nonmutagenic sulfuric acid esters of o-amidofluorenols.
    Smith BA, Gutmann HR, Springfield JR.
    Biochem Pharmacol; 1989 Nov 15; 38(22):3987-94. PubMed ID: 2597180
    [Abstract] [Full Text] [Related]

  • 2. Effect of bovine serum albumin on the extent of ortho rearrangement of N-(sulfooxy)-2-fluorenylacetamide and of enzymatically activated N-hydroxy-2-fluorenylacetamide and on the binding of reactive esters to nucleic acids.
    Kolanczyk RC, Gutmann HR, Rutks IR.
    Chem Res Toxicol; 1992 Nov 15; 5(2):274-9. PubMed ID: 1643258
    [Abstract] [Full Text] [Related]

  • 3. The catalytic effect of bovine serum albumin on the ortho rearrangement of the potential ultimate carcinogen, N-(sulfooxy)-2-(acetylamino)fluorene, generated enzymatically from N-hydroxy-2-(acetylamino)fluorene and evidence for substrate specificity of the enzymatic sulfonation of arylhydroxamic acids.
    Kolanczyk RC, Rutks IR, Gutmann HR.
    Chem Res Toxicol; 1991 Nov 15; 4(2):187-94. PubMed ID: 1782347
    [Abstract] [Full Text] [Related]

  • 4. Solvolysis and metabolic degradation, by rat liver, of the ultimate carcinogen, N-sulfonoxy-2-acetylaminofluorene.
    Smith BA, Springfield JR, Gutmann HR.
    Mol Pharmacol; 1987 Apr 15; 31(4):438-45. PubMed ID: 3574289
    [Abstract] [Full Text] [Related]

  • 5. Interaction of the synthetic ultimate carcinogens, N-sulfonoxy- and N-acetoxy-2-acetylaminofluorene, and of enzymatically activated N-hydroxy-2-acetylaminofluorene with nucleophiles.
    Smith BA, Springfield JR, Gutmann HR.
    Carcinogenesis; 1986 Mar 15; 7(3):405-11. PubMed ID: 3512117
    [Abstract] [Full Text] [Related]

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  • 7. Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells.
    Glowinski IB, Sanderson ND, Hayashi S, Thorgeirsson SS.
    Cancer Res; 1984 Mar 15; 44(3):1098-104. PubMed ID: 6692396
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  • 9. N-sulfoöxy-2-aminofluorene is the major ultimate electrophilic and carcinogenic metabolite of N-hydroxy-2-acetylaminofluorene in the livers of infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.
    Lai CC, Miller JA, Miller EC, Liem A.
    Carcinogenesis; 1985 Jul 15; 6(7):1037-45. PubMed ID: 3860305
    [Abstract] [Full Text] [Related]

  • 10. Reaction product inactivation of aryl sulfotransferase IV following electrophilic substitution by the sulfuric acid ester of N-hydroxy-2-acetylaminofluorene.
    Ringer DP, Norton TR, Self RR.
    Carcinogenesis; 1992 Jan 15; 13(1):107-12. PubMed ID: 1733562
    [Abstract] [Full Text] [Related]

  • 11. Correlation between clastogenicity and promotion activity in liver carcinogenesis by N-hydroxy-2-acetylaminofluorene, N-hydroxy-4'-fluoro-4-acetylaminobiphenyl and N-hydroxy-4-acetylaminobiphenyl.
    van de Poll ML, van der Hulst DA, Tates AD, Meerman JH.
    Carcinogenesis; 1990 Feb 15; 11(2):333-9. PubMed ID: 2302760
    [Abstract] [Full Text] [Related]

  • 12. Effect of glutathione depletion on the hepatotoxicity and covalent binding rat liver macromolecules of N-hydroxy-2-acetylaminofluorene.
    Meerman JH, Tijdens RB.
    Cancer Res; 1985 Mar 15; 45(3):1132-9. PubMed ID: 2578873
    [Abstract] [Full Text] [Related]

  • 13. New 9-stubstituted 3-N,O-diacetylhydroxylaminofluorenes: enhanced electrophilicity and mutagenicity. Derivatives of fluorene. 38.
    Cole CA, Pan HL, Fletcher TL.
    Cancer Lett; 1980 Mar 15; 9(1):61-6. PubMed ID: 7370977
    [Abstract] [Full Text] [Related]

  • 14. Role of sulfation in the formation of DNA adducts from N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Inhibition of N-acetylated aminofluorene adduct formation by pentachlorophenol.
    Meerman JH, Beland FA, Mulder GJ.
    Carcinogenesis; 1981 Mar 15; 2(5):413-6. PubMed ID: 7273322
    [Abstract] [Full Text] [Related]

  • 15. Self-catalyzed irreversible inactivation of rat hepatic aryl sulfotransferase IV by N-hydroxy-2-acetylaminofluorene.
    Mangold BL, Erickson J, Lohr C, McCann DJ, Mangold JB.
    Carcinogenesis; 1990 Sep 15; 11(9):1563-7. PubMed ID: 2401045
    [Abstract] [Full Text] [Related]

  • 16. Formation of DNA adducts from N-acetoxy-2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene in rat hemopoietic tissues in vivo.
    Vu VT, Grantham PH, Roller PP, Hankins WD, Wirth PJ, Thorgeirsson SS.
    Cancer Res; 1986 Jan 15; 46(1):233-8. PubMed ID: 3940194
    [Abstract] [Full Text] [Related]

  • 17. Aminofluorene-DNA adduct formation in Salmonella typhimurium exposed to the carcinogen N-hydroxy-2-acetylaminofluorene.
    Beranek DT, White GL, Heflich RH, Beland FA.
    Proc Natl Acad Sci U S A; 1982 Sep 15; 79(17):5175-8. PubMed ID: 6752940
    [Abstract] [Full Text] [Related]

  • 18. Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts.
    Lai CC, Miller EC, Miller JA, Liem A.
    Carcinogenesis; 1987 Mar 15; 8(3):471-8. PubMed ID: 3815742
    [Abstract] [Full Text] [Related]

  • 19. The role of N-sulfation in the N-hydroxy-2-acetylaminofluorene-mediated outgrowth of diethylnitrosamine-initiated hepatocytes to gamma-glutamyltranspeptidase-positive foci in male rat liver.
    Kroese ED, van de Poll ML, Mulder GJ, Meerman JH.
    Carcinogenesis; 1988 Nov 15; 9(11):1953-8. PubMed ID: 2902938
    [Abstract] [Full Text] [Related]

  • 20. Covalent binding of 2-acetylaminofluorene, 2-aminofluorene, and N-hydroxy-2-acetylaminofluorene to rat liver nuclear DNA and protein in vivo and in vitro.
    Stout DL, Hemminki K, Becker FF.
    Cancer Res; 1980 Oct 15; 40(10):3579-84. PubMed ID: 7438044
    [Abstract] [Full Text] [Related]


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