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Journal Abstract Search

137 related items for PubMed ID: 25982078

  • 1. Design, synthesis, and biological evaluation of a series of alkoxy-3-indolylacetic acids as peroxisome proliferator-activated receptor γ/δ agonists.
    Gim HJ, Li H, Jeong JH, Lee SJ, Sung MK, Song MY, Park BH, Oh SJ, Ryu JH, Jeon R.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3322-36. PubMed ID: 25982078
    [Abstract] [Full Text] [Related]

  • 2. A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
    Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.
    Eur J Pharmacol; 2008 Apr 14; 584(1):192-201. PubMed ID: 18346728
    [Abstract] [Full Text] [Related]

  • 3. Pharmacological profile of a novel, non-TZD PPARgamma agonist.
    Chen X, Osborne MC, Rybczynski PJ, Zeck R, Yang M, Xu J, Zhou L, Cryan E, Tang Y, Demarest KT.
    Diabetes Obes Metab; 2005 Sep 14; 7(5):536-46. PubMed ID: 16050946
    [Abstract] [Full Text] [Related]

  • 4. The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo.
    Li YY, Wu HS, Tang L, Feng CR, Yu JH, Li Y, Yang YS, Yang B, He QJ.
    Pharmacol Res; 2007 Oct 14; 56(4):335-43. PubMed ID: 17889553
    [Abstract] [Full Text] [Related]

  • 5. Sulfonylthiadiazoles with an unusual binding mode as partial dual peroxisome proliferator-activated receptor (PPAR) γ/δ agonists with high potency and in vivo efficacy.
    Keil S, Matter H, Schönafinger K, Glien M, Mathieu M, Marquette JP, Michot N, Haag-Diergarten S, Urmann M, Wendler W.
    ChemMedChem; 2011 Apr 04; 6(4):633-53. PubMed ID: 21400663
    [Abstract] [Full Text] [Related]

  • 6. KDT501, a derivative from hops, normalizes glucose metabolism and body weight in rodent models of diabetes.
    Konda VR, Desai A, Darland G, Grayson N, Bland JS.
    PLoS One; 2014 Apr 04; 9(1):e87848. PubMed ID: 24498211
    [Abstract] [Full Text] [Related]

  • 7. P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.
    Chen W, Zhou XB, Liu HY, Xu C, Wang LL, Li S.
    Br J Pharmacol; 2009 Jul 04; 157(5):724-35. PubMed ID: 19422369
    [Abstract] [Full Text] [Related]

  • 8. Design, Synthesis, and Biological Evaluation of Thiazolidine-2,4-dione Conjugates as PPAR-γ Agonists.
    Nazreen S, Alam MS, Hamid H, Shahar Yar M, Dhulap A, Alam P, Pasha MA, Bano S, Alam MM, Haider S, Kharbanda C, Ali Y, Pillai K.
    Arch Pharm (Weinheim); 2015 Jun 04; 348(6):421-32. PubMed ID: 25900064
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of a novel class of dual PPARgamma/delta agonists.
    Gonzalez IC, Lamar J, Iradier F, Xu Y, Winneroski LL, York J, Yumibe N, Zink R, Montrose-Rafizadeh C, Etgen GJ, Broderick CL, Oldham BA, Mantlo N.
    Bioorg Med Chem Lett; 2007 Feb 15; 17(4):1052-5. PubMed ID: 17129725
    [Abstract] [Full Text] [Related]

  • 10. Design and synthesis of alkoxyindolyl-3-acetic acid analogs as peroxisome proliferator-activated receptor-γ/δ agonists.
    Gim HJ, Li H, Lee E, Ryu JH, Jeon R.
    Bioorg Med Chem Lett; 2013 Jan 15; 23(2):513-7. PubMed ID: 23265886
    [Abstract] [Full Text] [Related]

  • 11. Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models.
    Kanda S, Nakashima R, Takahashi K, Tanaka J, Ogawa J, Ogata T, Yachi M, Araki K, Ohsumi J.
    J Pharmacol Sci; 2009 Oct 15; 111(2):155-66. PubMed ID: 19809220
    [Abstract] [Full Text] [Related]

  • 12. LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.
    Gilardi F, Giudici M, Mitro N, Maschi O, Guerrini U, Rando G, Maggi A, Cermenati G, Laghezza A, Loiodice F, Pochetti G, Lavecchia A, Caruso D, De Fabiani E, Bamberg K, Crestani M.
    J Biol Chem; 2014 Mar 07; 289(10):6908-6920. PubMed ID: 24451380
    [Abstract] [Full Text] [Related]

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  • 14. Peroxisome proliferator-activated receptor (PPAR)-gamma positively controls and PPARalpha negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels.
    Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G.
    Mol Pharmacol; 2009 Aug 07; 76(2):414-24. PubMed ID: 19483106
    [Abstract] [Full Text] [Related]

  • 15. PAM-1616, a selective peroxisome proliferator-activated receptor γ modulator with preserved anti-diabetic efficacy and reduced adverse effects.
    Kim MK, Chae YN, Choi SH, Moon HS, Son MH, Bae MH, Choi HH, Hur Y, Kim E, Park YH, Park CS, Kim JG, Lim JI, Shin CY.
    Eur J Pharmacol; 2011 Jan 15; 650(2-3):673-81. PubMed ID: 20974124
    [Abstract] [Full Text] [Related]

  • 16. Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice.
    Loffler M, Bilban M, Reimers M, Waldhäusl W, Stulnig TM.
    J Pharmacol Exp Ther; 2006 Feb 15; 316(2):797-804. PubMed ID: 16260581
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  • 20. Design and synthesis of benzoxazole containing indole analogs as peroxisome proliferator-activated receptor-γ/δ dual agonists.
    Gim HJ, Cheon YJ, Ryu JH, Jeon R.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):3057-61. PubMed ID: 21482466
    [Abstract] [Full Text] [Related]

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