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Journal Abstract Search

181 related items for PubMed ID: 25989889

  • 1. Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide.
    Matsunaga N, Suzuki K, Nakanishi T, Ogawa M, Imawaka H, Tamai I.
    Drug Metab Pharmacokinet; 2015 Apr; 30(2):142-8. PubMed ID: 25989889
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  • 3. Glucuronidation and subsequent biliary excretion of mycophenolic acid in rat sandwich-cultured hepatocytes.
    Tetsuka K, Gerst N, Tamura K, Masters JN.
    Drug Metab Pharmacokinet; 2014 Apr; 29(2):129-34. PubMed ID: 24025987
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  • 5. MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood.
    Berthier J, Benmameri M, Sauvage FL, Fabre G, Chantemargue B, Arnion H, Marquet P, Trouillas P, Picard N, Saint-Marcoux F.
    Xenobiotica; 2021 Jan; 51(1):105-114. PubMed ID: 32820679
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  • 7. Impact of calcineurin inhibitors on urinary excretion of mycophenolic acid and its glucuronide in kidney transplant recipients.
    Naito T, Mino Y, Otsuka A, Ushiyama T, Ito T, Ozono S, Kagawa Y, Kawakami J.
    J Clin Pharmacol; 2009 Jun; 49(6):710-8. PubMed ID: 19451405
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  • 8. Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats.
    Kobayashi M, Saitoh H, Kobayashi M, Tadano K, Takahashi Y, Hirano T.
    J Pharmacol Exp Ther; 2004 Jun; 309(3):1029-35. PubMed ID: 14978191
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  • 9. Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney.
    Wolff NA, Burckhardt BC, Burckhardt G, Oellerich M, Armstrong VW.
    Nephrol Dial Transplant; 2007 Sep; 22(9):2497-503. PubMed ID: 17526543
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  • 10. Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients.
    Colom H, Lloberas N, Andreu F, Caldés A, Torras J, Oppenheimer F, Sanchez-Plumed J, Gentil MA, Kuypers DR, Brunet M, Ekberg H, Grinyó JM.
    Kidney Int; 2014 Jun; 85(6):1434-43. PubMed ID: 24402086
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  • 11. Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3.
    Uwai Y, Motohashi H, Tsuji Y, Ueo H, Katsura T, Inui K.
    Biochem Pharmacol; 2007 Jun 30; 74(1):161-8. PubMed ID: 17462604
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  • 12. Characterization of intestinal absorption and enterohepatic circulation of mycophenolic Acid and its 7-O-glucuronide in rats.
    Saitoh H, Kobayashi M, Oda M, Nakasato K, Kobayashi M, Tadano K.
    Drug Metab Pharmacokinet; 2006 Oct 30; 21(5):406-13. PubMed ID: 17072094
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  • 13. Hepatic Disposition of Gemfibrozil and Its Major Metabolite Gemfibrozil 1-O-β-Glucuronide.
    Kimoto E, Li R, Scialis RJ, Lai Y, Varma MV.
    Mol Pharm; 2015 Nov 02; 12(11):3943-52. PubMed ID: 26378985
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  • 14. Inhibitory effect of ciprofloxacin on β-glucuronidase-mediated deconjugation of mycophenolic acid glucuronide.
    Kodawara T, Masuda S, Yano Y, Matsubara K, Nakamura T, Masada M.
    Biopharm Drug Dispos; 2014 Jul 02; 35(5):275-83. PubMed ID: 24615849
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  • 15. Development of Improved Dosing Regimens for Mycophenolate Mofetil Based on Population Pharmacokinetic Analyses in Adults with Lupus Nephritis.
    Abd Rahman AN, Tett SE, Abdul Gafor HA, McWhinney BC, Staatz CE.
    Eur J Drug Metab Pharmacokinet; 2017 Dec 02; 42(6):993-1004. PubMed ID: 28536776
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  • 16. Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.
    Hesselink DA, van Hest RM, Mathot RA, Bonthuis F, Weimar W, de Bruin RW, van Gelder T.
    Am J Transplant; 2005 May 02; 5(5):987-94. PubMed ID: 15816878
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  • 17. Role of Mrp2 in the hepatic disposition of mycophenolic acid and its glucuronide metabolites: effect of cyclosporine.
    Westley IS, Brogan LR, Morris RG, Evans AM, Sallustio BC.
    Drug Metab Dispos; 2006 Feb 02; 34(2):261-6. PubMed ID: 16272406
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  • 18. Mycophenolic acid and mycophenolic acid glucuronide pharmacokinetics in pediatric liver transplant recipients: effect of cyclosporine and tacrolimus comedication.
    Brown NW, Aw MM, Mieli-Vergani G, Dhawan A, Tredger JM.
    Ther Drug Monit; 2002 Oct 02; 24(5):598-606. PubMed ID: 12352931
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  • 19. Mycophenolic acid glucuronide is transported by multidrug resistance-associated protein 2 and this transport is not inhibited by cyclosporine, tacrolimus or sirolimus.
    Patel CG, Ogasawara K, Akhlaghi F.
    Xenobiotica; 2013 Mar 02; 43(3):229-35. PubMed ID: 22934787
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  • 20. Pharmacokinetics of mycophenolic acid and its phenolic-glucuronide and ACYl glucuronide metabolites in stable thoracic transplant recipients.
    Ting LS, Partovi N, Levy RD, Riggs KW, Ensom MH.
    Ther Drug Monit; 2008 Jun 02; 30(3):282-91. PubMed ID: 18520599
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