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111 related items for PubMed ID: 25991719

  • 1. Enhanced expression of epithelial sodium channels causes salt-induced hypertension in mice through inhibition of the α2-isoform of Na+, K+-ATPase.
    Leenen FH, Hou X, Wang HW, Ahmad M.
    Physiol Rep; 2015 May; 3(5):. PubMed ID: 25991719
    [Abstract] [Full Text] [Related]

  • 2. Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.
    Van Huysse JW, Amin MS, Yang B, Leenen FH.
    Hypertension; 2012 Sep; 60(3):691-6. PubMed ID: 22802227
    [Abstract] [Full Text] [Related]

  • 3. Hypertension from chronic central sodium chloride in mice is mediated by the ouabain-binding site on the Na,K-ATPase α₂-isoform.
    Van Huysse JW, Dostanic I, Lingrel JB, Hou X, Wu H.
    Am J Physiol Heart Circ Physiol; 2011 Nov; 301(5):H2147-53. PubMed ID: 21856907
    [Abstract] [Full Text] [Related]

  • 4. Enhanced pressor response to increased CSF sodium concentration and to central ANG I in heterozygous alpha2 Na+ -K+ -ATPase knockout mice.
    Hou X, Theriault SF, Dostanic-Larson I, Moseley AE, Lingrel JB, Wu H, Dean S, Van Huysse JW.
    Am J Physiol Regul Integr Comp Physiol; 2009 May; 296(5):R1427-38. PubMed ID: 19244589
    [Abstract] [Full Text] [Related]

  • 5. Sodium transport in the choroid plexus and salt-sensitive hypertension.
    Amin MS, Reza E, Wang H, Leenen FH.
    Hypertension; 2009 Oct; 54(4):860-7. PubMed ID: 19635991
    [Abstract] [Full Text] [Related]

  • 6. Low efficiency of functional translation of ouabain-resistant α2-Na(+),K(+)-ATPase mRNA in C7-MDCK epithelial cells.
    Akimova OA, Van Huysse J, Tremblay J, Orlov SN.
    Can J Physiol Pharmacol; 2012 Jan; 90(1):83-8. PubMed ID: 22188474
    [Abstract] [Full Text] [Related]

  • 7. Brain amiloride-sensitive Phe-Met-Arg-Phe-NH(2)--gated Na(+) channels and Na(+)-induced sympathoexcitation and hypertension.
    Huang BS, Leenen FH.
    Hypertension; 2002 Feb; 39(2 Pt 2):557-61. PubMed ID: 11882607
    [Abstract] [Full Text] [Related]

  • 8. The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension.
    Leenen FH.
    Biochim Biophys Acta; 2010 Dec; 1802(12):1132-9. PubMed ID: 20230892
    [Abstract] [Full Text] [Related]

  • 9. Effects of central sodium on epithelial sodium channels in rat brain.
    Wang HW, Amin MS, El-Shahat E, Huang BS, Tuana BS, Leenen FH.
    Am J Physiol Regul Integr Comp Physiol; 2010 Jul; 299(1):R222-33. PubMed ID: 20427723
    [Abstract] [Full Text] [Related]

  • 10. Endogenous brain Na pumps, brain ouabain-like substance and the alpha2 isoform in salt-dependent hypertension.
    Van Huysse JW.
    Pathophysiology; 2007 Dec; 14(3-4):213-20. PubMed ID: 17980562
    [Abstract] [Full Text] [Related]

  • 11. Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway.
    Gille T, Randrianarison-Pellan N, Goolaerts A, Dard N, Uzunhan Y, Ferrary E, Hummler E, Clerici C, Planès C.
    Am J Respir Cell Mol Biol; 2014 Mar; 50(3):526-37. PubMed ID: 24093724
    [Abstract] [Full Text] [Related]

  • 12. Systemic hypertension: the roles of salt, vascular Na+/K+ ATPase and the endogenous glycosides, ouabain and marinobufagenin.
    Hauck C, Frishman WH.
    Cardiol Rev; 2012 Mar; 20(3):130-8. PubMed ID: 22183064
    [Abstract] [Full Text] [Related]

  • 13. An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in mice.
    Minegishi S, Ishigami T, Kino T, Chen L, Nakashima-Sasaki R, Araki N, Yatsu K, Fujita M, Umemura S.
    Sci Rep; 2016 Jun 03; 6():27137. PubMed ID: 27256588
    [Abstract] [Full Text] [Related]

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  • 15. Pivotal role of α2 Na+ pumps and their high affinity ouabain binding site in cardiovascular health and disease.
    Blaustein MP, Chen L, Hamlyn JM, Leenen FH, Lingrel JB, Wier WG, Zhang J.
    J Physiol; 2016 Nov 01; 594(21):6079-6103. PubMed ID: 27350568
    [Abstract] [Full Text] [Related]

  • 16. Eplerenone-Resistant Salt-Sensitive Hypertension in Nedd4-2 C2 KO Mice.
    Kino T, Ishigami T, Murata T, Doi H, Nakashima-Sasaki R, Chen L, Sugiyama M, Azushima K, Wakui H, Minegishi S, Tamura K.
    Int J Mol Sci; 2017 Jun 11; 18(6):. PubMed ID: 28604611
    [Abstract] [Full Text] [Related]

  • 17. An Isoform of Nedd4-2 Plays a Pivotal Role in Electrophysiological Cardiac Abnormalities.
    Minegishi S, Ishigami T, Kawamura H, Kino T, Chen L, Nakashima-Sasaki R, Doi H, Azushima K, Wakui H, Chiba Y, Tamura K.
    Int J Mol Sci; 2017 Jun 14; 18(6):. PubMed ID: 28613240
    [Abstract] [Full Text] [Related]

  • 18. NEDD4-2 and salt-sensitive hypertension.
    Rizzo F, Staub O.
    Curr Opin Nephrol Hypertens; 2015 Mar 14; 24(2):111-6. PubMed ID: 25602517
    [Abstract] [Full Text] [Related]

  • 19. Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.
    Lorenz JN, Dostanic-Larson I, Shull GE, Lingrel JB.
    J Am Soc Nephrol; 2006 Sep 14; 17(9):2457-63. PubMed ID: 16870707
    [Abstract] [Full Text] [Related]

  • 20. The central role of the brain in salt-sensitive hypertension.
    Huang BS, Amin MS, Leenen FH.
    Curr Opin Cardiol; 2006 Jul 14; 21(4):295-304. PubMed ID: 16755197
    [Abstract] [Full Text] [Related]

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