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127 related items for PubMed ID: 2600079

  • 1. Inactivation of monoamine oxidase by 3,3-dimethyl analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenyl-2,3-dihydropyridinium ion. Dramatic effect of beta-mercaptoethanol on substrate turnover and enzyme inactivation.
    Hiebert CK, Sayre LM, Silverman RB.
    J Biol Chem; 1989 Dec 25; 264(36):21516-21. PubMed ID: 2600079
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  • 2. Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines.
    Krueger MJ, McKeown K, Ramsay RR, Youngster SK, Singer TP.
    Biochem J; 1990 May 15; 268(1):219-24. PubMed ID: 2344359
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  • 3. Reversible inhibition and mechanism-based irreversible inactivation of monoamine oxidases by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Singer TP, Salach JI, Crabtree D.
    Biochem Biophys Res Commun; 1985 Mar 15; 127(2):707-12. PubMed ID: 3872126
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  • 4. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A.
    Basma AN, Heikkila RE, Nicklas WJ, Giovanni A, Geller HM.
    J Neurochem; 1990 Sep 15; 55(3):870-7. PubMed ID: 2384758
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  • 5. Deuterium isotope effect measurements on the interactions of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidase B.
    Ottoboni S, Caldera P, Trevor A, Castagnoli N.
    J Biol Chem; 1989 Aug 15; 264(23):13684-8. PubMed ID: 2788162
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  • 6. Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases.
    Singer TP, Salach JI, Castagnoli N, Trevor A.
    Biochem J; 1986 May 01; 235(3):785-9. PubMed ID: 3489461
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  • 7. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
    Herraiz T, Arán VJ, Guillén H.
    Free Radic Res; 2009 Oct 01; 43(10):975-84. PubMed ID: 19669997
    [Abstract] [Full Text] [Related]

  • 8. Studies on the 1-methyl-4-phenyl-2,3-dihydropyridinium species 2,3-MPDP+, the monoamine oxidase catalyzed oxidation product of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Peterson LA, Caldera PS, Trevor A, Chiba K, Castagnoli N.
    J Med Chem; 1985 Oct 01; 28(10):1432-6. PubMed ID: 3876442
    [Abstract] [Full Text] [Related]

  • 9. Involvement of hepatic aldehyde oxidase in conversion of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+) to 1-methyl-4-phenyl-5,6-dihydro-2-pyridone.
    Yoshihara S, Ohta S.
    Arch Biochem Biophys; 1998 Dec 01; 360(1):93-8. PubMed ID: 9826433
    [Abstract] [Full Text] [Related]

  • 10. 1-Methyl-4-phenyl-2,3-dihydropyridinium is transformed by ubiquinone to the selective nigrostriatal toxin 1-methyl-4-phenylpyridinium.
    Shi H, Noguchi N, Xu Y, Niki E.
    FEBS Lett; 1999 Nov 19; 461(3):196-200. PubMed ID: 10567696
    [Abstract] [Full Text] [Related]

  • 11. Mutagenicity of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and its metabolites.
    Cashman JR.
    Toxicology; 1987 Feb 19; 43(2):173-82. PubMed ID: 2949395
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  • 13. Metabolic studies on the nigrostriatal toxin MPTP and its MAO B generated dihydropyridinium metabolite MPDP+.
    Wu E, Shinka T, Caldera-Munoz P, Yoshizumi H, Trevor A, Castagnoli N.
    Chem Res Toxicol; 1988 Feb 19; 1(3):186-94. PubMed ID: 2979730
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  • 18. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Pretorius A, Ogunrombi MO, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8813-7. PubMed ID: 18799315
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  • 19. Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.
    Herraiz T, Guillén H.
    Food Chem Toxicol; 2011 Aug 01; 49(8):1773-81. PubMed ID: 21554916
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