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Journal Abstract Search

127 related items for PubMed ID: 2600079

  • 41. Photoinactivation of B-type monoamine oxidase by a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite.
    Buckman TD, Eiduson S.
    J Biol Chem; 1985 Oct 05; 260(22):11899-902. PubMed ID: 3876335
    [Abstract] [Full Text] [Related]

  • 42. Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Chiba K, Peterson LA, Castagnoli KP, Trevor AJ, Castagnoli N.
    Drug Metab Dispos; 1985 Oct 05; 13(3):342-7. PubMed ID: 2861994
    [Abstract] [Full Text] [Related]

  • 43. Activation and deactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by cytochrome P450 enzymes and flavin-containing monooxygenases in common marmosets (Callithrix jacchus).
    Uehara S, Uno Y, Inoue T, Murayama N, Shimizu M, Sasaki E, Yamazaki H.
    Drug Metab Dispos; 2015 May 05; 43(5):735-42. PubMed ID: 25735838
    [Abstract] [Full Text] [Related]

  • 44. Further insight into the mode of action of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Gessner W, Brossi A, Shen RS, Abell CW.
    FEBS Lett; 1985 Apr 22; 183(2):345-8. PubMed ID: 3872811
    [Abstract] [Full Text] [Related]

  • 45. Mechanism-based inactivation of mitochondrial monoamine oxidase by N-(1-methylcyclopropyl)benzylamine.
    Silverman RB, Yamasaki RB.
    Biochemistry; 1984 Mar 13; 23(6):1322-32. PubMed ID: 6712946
    [Abstract] [Full Text] [Related]

  • 46. Processing of MPTP by monoamine oxidases: implications for molecular toxicology.
    Trevor AJ, Singer TP, Ramsay RR, Castagnoli N.
    J Neural Transm Suppl; 1987 Mar 13; 23():73-89. PubMed ID: 3295117
    [Abstract] [Full Text] [Related]

  • 47. Characterization of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) binding sites in C57BL/6 mouse brain: mutual effects of monoamine oxidase inhibitors and sigma ligands on MPTP and sigma binding sites.
    Itzhak Y, Mash D, Zhang SH, Stein I.
    Mol Pharmacol; 1991 Mar 13; 39(3):385-93. PubMed ID: 1848660
    [Abstract] [Full Text] [Related]

  • 48. Toxicity of the 1-methyl-4-phenyl-2,3-dihydropyridinium and 1-methyl-4-phenylpyridinium species in primary cultures of mouse astrocytes.
    Wu EY, Langston JW, Di Monte DA.
    J Pharmacol Exp Ther; 1992 Jul 13; 262(1):225-30. PubMed ID: 1625201
    [Abstract] [Full Text] [Related]

  • 49. Production and disposition of 1-methyl-4-phenylpyridinium in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    Glia; 1992 Jul 13; 5(1):48-55. PubMed ID: 1311704
    [Abstract] [Full Text] [Related]

  • 50. Inhibition of acetylcholinesterase by the neurotoxicant, 1-methyl-4-phenyl-2,3-dihydropyridinium ion.
    Zang LY, Misra HP.
    Arch Biochem Biophys; 1996 Dec 01; 336(1):147-50. PubMed ID: 8951045
    [Abstract] [Full Text] [Related]

  • 51. Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Naiman N, Rollema H, Johnson E, Castagnoli N.
    Chem Res Toxicol; 1990 Dec 01; 3(2):133-8. PubMed ID: 2130940
    [Abstract] [Full Text] [Related]

  • 52. Studies on 1,2,3,6-tetrahydropyridine derivatives as potential monoamine oxidase inactivators.
    Hall L, Murray S, Castagnoli K, Castagnoli N.
    Chem Res Toxicol; 1992 Dec 01; 5(5):625-33. PubMed ID: 1446001
    [Abstract] [Full Text] [Related]

  • 53. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues. Inactivation of monoamine oxidase by conformationally rigid analogues of N,N-dimethylcinnamylamine.
    Hiebert CK, Silverman RB.
    J Med Chem; 1988 Aug 01; 31(8):1566-70. PubMed ID: 3260955
    [Abstract] [Full Text] [Related]

  • 54. Design, synthesis, and biological evaluation of novel 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine analogs of MPTP.
    Zhao Z, Dalvie D, Naiman N, Castagnoli K, Castagnoli N.
    J Med Chem; 1992 Nov 13; 35(23):4473-8. PubMed ID: 1447747
    [Abstract] [Full Text] [Related]

  • 55. Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP as monoamine oxidase A and B substrates.
    Kalgutkar AS, Castagnoli K, Hall A, Castagnoli N.
    J Med Chem; 1994 Apr 01; 37(7):944-9. PubMed ID: 8151621
    [Abstract] [Full Text] [Related]

  • 56. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.
    Youngster SK, Nicklas WJ, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun 01; 249(3):829-35. PubMed ID: 2786565
    [Abstract] [Full Text] [Related]

  • 57. Oxidation of 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine, a 1-amino analog of MPTP, by type A and B monoamine oxidase.
    Umeda M, Aoyama S, Kaiya T, Kohda K, Maruyama W, Naoi M.
    J Neural Transm (Vienna); 1998 Jun 01; 105(10-12):1253-64. PubMed ID: 9928894
    [Abstract] [Full Text] [Related]

  • 58. Pharmacological properties of the MPTP analog trans-1-methyl-4-[4-dimethylaminophenylethenyl]-1,2,3,6-tetrahydropyridine and its pyridinium metabolite in mouse brain synaptosomes: a potential visual marker for substrates of MPTP-induced neurotoxicity.
    Klein BG, Kirby ML, Freeborn ER, Bloomquist JR.
    Prog Neuropsychopharmacol Biol Psychiatry; 2001 Apr 01; 25(3):591-608. PubMed ID: 11370999
    [Abstract] [Full Text] [Related]

  • 59. Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP.
    Salach JI, Singer TP, Castagnoli N, Trevor A.
    Biochem Biophys Res Commun; 1984 Dec 14; 125(2):831-5. PubMed ID: 6335034
    [Abstract] [Full Text] [Related]

  • 60. Deprenyl antagonizes acute lethality of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Fuller RW, Hemrick-Luecke SK, Perry KW.
    J Pharmacol Exp Ther; 1988 Nov 14; 247(2):531-5. PubMed ID: 3141609
    [Abstract] [Full Text] [Related]

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