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351 related items for PubMed ID: 26008232

  • 1. Perfringolysin O: The Underrated Clostridium perfringens Toxin?
    Verherstraeten S, Goossens E, Valgaeren B, Pardon B, Timbermont L, Haesebrouck F, Ducatelle R, Deprez P, Wade KR, Tweten R, Van Immerseel F.
    Toxins (Basel); 2015 May 14; 7(5):1702-21. PubMed ID: 26008232
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  • 2. The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells.
    Verherstraeten S, Goossens E, Valgaeren B, Pardon B, Timbermont L, Vermeulen K, Schauvliege S, Haesebrouck F, Ducatelle R, Deprez P, Van Immerseel F.
    Vet Res; 2013 Jun 19; 44(1):45. PubMed ID: 23782465
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  • 3. Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy.
    Shepard LA, Heuck AP, Hamman BD, Rossjohn J, Parker MW, Ryan KR, Johnson AE, Tweten RK.
    Biochemistry; 1998 Oct 13; 37(41):14563-74. PubMed ID: 9772185
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  • 4. Non-toxic perfringolysin O and α-toxin derivatives as potential vaccine candidates against bovine necrohaemorrhagic enteritis.
    Verherstraeten S, Goossens E, Valgaeren B, Pardon B, Timbermont L, Haesebrouck F, Ducatelle R, Deprez P, Van Immerseel F.
    Vet J; 2016 Nov 13; 217():89-94. PubMed ID: 27810219
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  • 5. Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis.
    Goossens E, Verherstraeten S, Valgaeren BR, Pardon B, Timbermont L, Schauvliege S, Rodrigo-Mocholí D, Haesebrouck F, Ducatelle R, Deprez PR, Van Immerseel F.
    BMC Vet Res; 2016 Jun 13; 12(1):101. PubMed ID: 27297520
    [Abstract] [Full Text] [Related]

  • 6. Phospholipid hydrolysis caused by Clostridium perfringens α-toxin facilitates the targeting of perfringolysin O to membrane bilayers.
    Moe PC, Heuck AP.
    Biochemistry; 2010 Nov 09; 49(44):9498-507. PubMed ID: 20886855
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  • 7. Immunogenic and neutralization efficacy of recombinant perfringolysin O of Clostridium perfringens and its C-terminal receptor-binding domain in a murine model.
    Singh A, Rawat P, Choudhury D, Dixit A.
    Immunol Res; 2022 Apr 09; 70(2):240-255. PubMed ID: 35032316
    [Abstract] [Full Text] [Related]

  • 8. Effects of Clostridium perfringens alpha-toxin (PLC) and perfringolysin O (PFO) on cytotoxicity to macrophages, on escape from the phagosomes of macrophages, and on persistence of C. perfringens in host tissues.
    O'Brien DK, Melville SB.
    Infect Immun; 2004 Sep 09; 72(9):5204-15. PubMed ID: 15322015
    [Abstract] [Full Text] [Related]

  • 9. R468A mutation in perfringolysin O destabilizes toxin structure and induces membrane fusion.
    Kulma M, Kacprzyk-Stokowiec A, Kwiatkowska K, Traczyk G, Sobota A, Dadlez M.
    Biochim Biophys Acta Biomembr; 2017 Jun 09; 1859(6):1075-1088. PubMed ID: 28263714
    [Abstract] [Full Text] [Related]

  • 10. Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy.
    Dang TX, Hotze EM, Rouiller I, Tweten RK, Wilson-Kubalek EM.
    J Struct Biol; 2005 Apr 09; 150(1):100-8. PubMed ID: 15797734
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  • 13. Enhanced production of phospholipase C and perfringolysin O (alpha and theta toxins) in a gatifloxacin-resistant strain of Clostridium perfringens.
    Rafii F, Park M, Bryant AE, Johnson SJ, Wagner RD.
    Antimicrob Agents Chemother; 2008 Mar 09; 52(3):895-900. PubMed ID: 18160514
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  • 17. The presence of differentiated C2C12 muscle cells enhances toxin production and growth by Clostridium perfringens type A strain ATCC3624.
    Li J, Sayeed S, McClane BA.
    Virulence; 2024 Dec 09; 15(1):2388219. PubMed ID: 39192628
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  • 18. Crucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study.
    Kacprzyk-Stokowiec A, Kulma M, Traczyk G, Kwiatkowska K, Sobota A, Dadlez M.
    J Biol Chem; 2014 Oct 10; 289(41):28738-52. PubMed ID: 25164812
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  • 19. Modifications in perfringolysin O domain 4 alter the cholesterol concentration threshold required for binding.
    Johnson BB, Moe PC, Wang D, Rossi K, Trigatti BL, Heuck AP.
    Biochemistry; 2012 Apr 24; 51(16):3373-82. PubMed ID: 22482748
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  • 20. Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene.
    Awad MM, Bryant AE, Stevens DL, Rood JI.
    Mol Microbiol; 1995 Jan 24; 15(2):191-202. PubMed ID: 7746141
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