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193 related items for PubMed ID: 26025967

  • 1. Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit.
    Weltzin MM, Schulte MK.
    J Pharmacol Exp Ther; 2015 Aug; 354(2):184-94. PubMed ID: 26025967
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological characterization of the allosteric modulator desformylflustrabromine and its interaction with alpha4beta2 neuronal nicotinic acetylcholine receptor orthosteric ligands.
    Weltzin MM, Schulte MK.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):917-26. PubMed ID: 20516140
    [Abstract] [Full Text] [Related]

  • 3. Desformylflustrabromine (dFBr), a positive allosteric modulator of the α4β2 nicotinic receptor modulates the hypnotic response to ethanol.
    DeCristofano L, Decker S, Schulte MK, Suryanarayanan A.
    Alcohol; 2021 Jun 01; 93():35-44. PubMed ID: 33652092
    [Abstract] [Full Text] [Related]

  • 4. Allosteric modulator Desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid(1-42) peptide.
    Pandya A, Yakel JL.
    J Mol Neurosci; 2011 Sep 01; 45(1):42-7. PubMed ID: 21424792
    [Abstract] [Full Text] [Related]

  • 5. Allosteric modulation of alpha4beta2 nicotinic acetylcholine receptors by HEPES.
    Weltzin MM, Huang Y, Schulte MK.
    Eur J Pharmacol; 2014 Jun 05; 732():159-68. PubMed ID: 22732654
    [Abstract] [Full Text] [Related]

  • 6. Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms.
    Hamouda AK, Bautista MR, Akinola LS, Alkhlaif Y, Jackson A, Carper M, Toma WB, Garai S, Chen YC, Thakur GA, Fowler CD, Damaj MI.
    Neuropharmacology; 2021 Jun 01; 190():108568. PubMed ID: 33878302
    [Abstract] [Full Text] [Related]

  • 7. Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.
    Wang ZJ, Deba F, Mohamed TS, Chiara DC, Ramos K, Hamouda AK.
    J Biol Chem; 2017 Jun 16; 292(24):9988-10001. PubMed ID: 28446611
    [Abstract] [Full Text] [Related]

  • 8. LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor.
    Deba F, Ali HI, Tairu A, Ramos K, Ali J, Hamouda AK.
    Sci Rep; 2018 Jan 19; 8(1):1249. PubMed ID: 29352227
    [Abstract] [Full Text] [Related]

  • 9. Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain.
    Bagdas D, Ergun D, Jackson A, Toma W, Schulte MK, Damaj MI.
    Eur J Pain; 2018 Jan 19; 22(1):84-93. PubMed ID: 28809075
    [Abstract] [Full Text] [Related]

  • 10. des-Formylflustrabromine (dFBr): A Structure-Activity Study on Its Ability To Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors.
    Dukat M, Jain A, German N, Ferrara-Pontoriero R, Huang Y, Ma Y, Schulte MK, Glennon RA.
    ACS Chem Neurosci; 2018 Dec 19; 9(12):2984-2996. PubMed ID: 30028943
    [Abstract] [Full Text] [Related]

  • 11. Positive allosteric modulation of α4β2 nicotinic acetylcholine receptors as a new approach to smoking reduction: evidence from a rat model of nicotine self-administration.
    Liu X.
    Psychopharmacology (Berl); 2013 Nov 19; 230(2):203-13. PubMed ID: 23712602
    [Abstract] [Full Text] [Related]

  • 12. Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor.
    Hamouda AK, Wang ZJ, Stewart DS, Jain AD, Glennon RA, Cohen JB.
    Mol Pharmacol; 2015 Jul 19; 88(1):1-11. PubMed ID: 25870334
    [Abstract] [Full Text] [Related]

  • 13. Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms.
    Weltzin MM, George AA, Lukas RJ, Whiteaker P.
    PLoS One; 2019 Jul 19; 14(3):e0213143. PubMed ID: 30845161
    [Abstract] [Full Text] [Related]

  • 14. Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine.
    German N, Kim JS, Jain A, Dukat M, Pandya A, Ma Y, Weltzin M, Schulte MK, Glennon RA.
    J Med Chem; 2011 Oct 27; 54(20):7259-67. PubMed ID: 21905680
    [Abstract] [Full Text] [Related]

  • 15. Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.
    Hamouda AK, Deba F, Wang ZJ, Cohen JB.
    Mol Pharmacol; 2016 May 27; 89(5):575-84. PubMed ID: 26976945
    [Abstract] [Full Text] [Related]

  • 16. Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats.
    Nikiforuk A, Litwa E, Krawczyk M, Popik P, Arias H.
    Pharmacol Rep; 2020 Jun 27; 72(3):589-599. PubMed ID: 32207091
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of desformylflustrabromine and its evaluation as an alpha4beta2 and alpha7 nACh receptor modulator.
    Kim JS, Padnya A, Weltzin M, Edmonds BW, Schulte MK, Glennon RA.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4855-60. PubMed ID: 17604168
    [Abstract] [Full Text] [Related]

  • 18. Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.
    Lucero LM, Weltzin MM, Eaton JB, Cooper JF, Lindstrom JM, Lukas RJ, Whiteaker P.
    J Biol Chem; 2016 Jan 29; 291(5):2444-59. PubMed ID: 26644472
    [Abstract] [Full Text] [Related]

  • 19. Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy.
    Weltzin MM, Lindstrom JM, Lukas RJ, Whiteaker P.
    Neuropharmacology; 2016 Mar 29; 102():158-73. PubMed ID: 26561946
    [Abstract] [Full Text] [Related]

  • 20. Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats.
    Deba F, Ramos K, Vannoy M, Munoz K, Akinola LS, Damaj MI, Hamouda AK.
    Molecules; 2020 Jun 25; 25(12):. PubMed ID: 32630476
    [Abstract] [Full Text] [Related]

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