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Journal Abstract Search

360 related items for PubMed ID: 26037925

  • 1. Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
    Pällmann N, Braig M, Sievert H, Preukschas M, Hermans-Borgmeyer I, Schweizer M, Nagel CH, Neumann M, Wild P, Haralambieva E, Hagel C, Bokemeyer C, Hauber J, Balabanov S.
    J Biol Chem; 2015 Jul 24; 290(30):18343-60. PubMed ID: 26037925
    [Abstract] [Full Text] [Related]

  • 2. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
    Park JH, Dias CA, Lee SB, Valentini SR, Sokabe M, Fraser CS, Park MH.
    Protein Eng Des Sel; 2011 Mar 24; 24(3):301-9. PubMed ID: 21131325
    [Abstract] [Full Text] [Related]

  • 3. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
    Park MH.
    J Biochem; 2006 Feb 24; 139(2):161-9. PubMed ID: 16452303
    [Abstract] [Full Text] [Related]

  • 4. Protein-protein-interaction network organization of the hypusine modification system.
    Sievert H, Venz S, Platas-Barradas O, Dhople VM, Schaletzky M, Nagel CH, Braig M, Preukschas M, Pällmann N, Bokemeyer C, Brümmendorf TH, Pörtner R, Walther R, Duncan KE, Hauber J, Balabanov S.
    Mol Cell Proteomics; 2012 Nov 24; 11(11):1289-305. PubMed ID: 22888148
    [Abstract] [Full Text] [Related]

  • 5. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
    Wolff EC, Kang KR, Kim YS, Park MH.
    Amino Acids; 2007 Aug 24; 33(2):341-50. PubMed ID: 17476569
    [Abstract] [Full Text] [Related]

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  • 7. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    Preukschas M, Hagel C, Schulte A, Weber K, Lamszus K, Sievert H, Pällmann N, Bokemeyer C, Hauber J, Braig M, Balabanov S.
    PLoS One; 2012 Aug 24; 7(8):e43468. PubMed ID: 22927971
    [Abstract] [Full Text] [Related]

  • 8. Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment.
    Park MH, Kar RK, Banka S, Ziegler A, Chung WK.
    Amino Acids; 2022 Apr 24; 54(4):485-499. PubMed ID: 34273022
    [Abstract] [Full Text] [Related]

  • 9. Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.
    Kar RK, Hanner AS, Starost MF, Springer D, Mastracci TL, Mirmira RG, Park MH.
    J Biol Chem; 2021 Nov 24; 297(5):101333. PubMed ID: 34688659
    [Abstract] [Full Text] [Related]

  • 10. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
    Schultz CR, Geerts D, Mooney M, El-Khawaja R, Koster J, Bachmann AS.
    Biochem J; 2018 Jan 31; 475(2):531-545. PubMed ID: 29295892
    [Abstract] [Full Text] [Related]

  • 11. The Many Faces of Hypusinated eIF5A: Cell Context-Specific Effects of the Hypusine Circuit and Implications for Human Health.
    Nakanishi S, Cleveland JL.
    Int J Mol Sci; 2024 Jul 26; 25(15):. PubMed ID: 39125743
    [Abstract] [Full Text] [Related]

  • 12. Marked elevation of hypusine formation activity on eukaryotic initiation factor 5A in v-HA-RAS transformed mouse NIH3T3 cells.
    Chen ZP, Chen KY.
    Cancer Lett; 1997 May 19; 115(2):235-41. PubMed ID: 9149130
    [Abstract] [Full Text] [Related]

  • 13. Interaction of eukaryotic initiation factor 5A with the human immunodeficiency virus type 1 Rev response element RNA and U6 snRNA requires deoxyhypusine or hypusine modification.
    Liu YP, Nemeroff M, Yan YP, Chen KY.
    Biol Signals; 1997 May 19; 6(3):166-74. PubMed ID: 9285100
    [Abstract] [Full Text] [Related]

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  • 15. The deoxyhypusine synthase mutant dys1-1 reveals the association of eIF5A and Asc1 with cell wall integrity.
    Galvão FC, Rossi D, Silveira Wda S, Valentini SR, Zanelli CF.
    PLoS One; 2013 May 19; 8(4):e60140. PubMed ID: 23573236
    [Abstract] [Full Text] [Related]

  • 16. Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.
    Nakanishi S, Cleveland JL.
    Amino Acids; 2016 Oct 19; 48(10):2353-62. PubMed ID: 27357307
    [Abstract] [Full Text] [Related]

  • 17. Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine.
    Park MH, Wolff EC, Smit-McBride Z, Hershey JW, Folk JE.
    J Biol Chem; 1991 May 05; 266(13):7988-94. PubMed ID: 1850732
    [Abstract] [Full Text] [Related]

  • 18. Functional significance of eIF5A and its hypusine modification in eukaryotes.
    Park MH, Nishimura K, Zanelli CF, Valentini SR.
    Amino Acids; 2010 Feb 05; 38(2):491-500. PubMed ID: 19997760
    [Abstract] [Full Text] [Related]

  • 19. Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.
    Nishimura K, Lee SB, Park JH, Park MH.
    Amino Acids; 2012 Feb 05; 42(2-3):703-10. PubMed ID: 21850436
    [Abstract] [Full Text] [Related]

  • 20. Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts.
    Chen ZP, Chen KY.
    J Cell Physiol; 1997 Mar 05; 170(3):248-54. PubMed ID: 9066781
    [Abstract] [Full Text] [Related]

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