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Journal Abstract Search

571 related items for PubMed ID: 26041293

  • 1. Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis.
    Wang Y, Sun Y, Wu A, Xu S, Pan R, Zeng C, Jin X, Ge X, Shi Z, Ahola T, Chen Y, Guo D.
    J Virol; 2015 Aug; 89(16):8416-27. PubMed ID: 26041293
    [Abstract] [Full Text] [Related]

  • 2. Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.
    Lugari A, Betzi S, Decroly E, Bonnaud E, Hermant A, Guillemot JC, Debarnot C, Borg JP, Bouvet M, Canard B, Morelli X, Lécine P.
    J Biol Chem; 2010 Oct 22; 285(43):33230-33241. PubMed ID: 20699222
    [Abstract] [Full Text] [Related]

  • 3. Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
    Chen Y, Su C, Ke M, Jin X, Xu L, Zhang Z, Wu A, Sun Y, Yang Z, Tien P, Ahola T, Liang Y, Liu X, Guo D.
    PLoS Pathog; 2011 Oct 22; 7(10):e1002294. PubMed ID: 22022266
    [Abstract] [Full Text] [Related]

  • 4. Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2'-O-methyltransferase activity of nsp10/nsp16 complex.
    Ke M, Chen Y, Wu A, Sun Y, Su C, Wu H, Jin X, Tao J, Wang Y, Ma X, Pan JA, Guo D.
    Virus Res; 2012 Aug 22; 167(2):322-8. PubMed ID: 22659295
    [Abstract] [Full Text] [Related]

  • 5. Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.
    Aouadi W, Blanjoie A, Vasseur JJ, Debart F, Canard B, Decroly E.
    J Virol; 2017 Mar 01; 91(5):. PubMed ID: 28031370
    [Abstract] [Full Text] [Related]

  • 6. Structural and functional insights into the 2'-O-methyltransferase of SARS-CoV-2.
    Deng J, Gong F, Li Y, Tan X, Liu X, Yang S, Chen X, Wang H, Liu Q, Shen C, Zhou L, Chen Y.
    Virol Sin; 2024 Aug 01; 39(4):619-631. PubMed ID: 38969340
    [Abstract] [Full Text] [Related]

  • 7. Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.
    Menachery VD, Yount BL, Josset L, Gralinski LE, Scobey T, Agnihothram S, Katze MG, Baric RS.
    J Virol; 2014 Apr 01; 88(8):4251-64. PubMed ID: 24478444
    [Abstract] [Full Text] [Related]

  • 8. Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.
    Case JB, Ashbrook AW, Dermody TS, Denison MR.
    J Virol; 2016 Aug 15; 90(16):7248-7256. PubMed ID: 27252528
    [Abstract] [Full Text] [Related]

  • 9. Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes.
    Bouvet M, Lugari A, Posthuma CC, Zevenhoven JC, Bernard S, Betzi S, Imbert I, Canard B, Guillemot JC, Lécine P, Pfefferle S, Drosten C, Snijder EJ, Decroly E, Morelli X.
    J Biol Chem; 2014 Sep 12; 289(37):25783-96. PubMed ID: 25074927
    [Abstract] [Full Text] [Related]

  • 10. SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3.
    Schindewolf C, Lokugamage K, Vu MN, Johnson BA, Scharton D, Plante JA, Kalveram B, Crocquet-Valdes PA, Sotcheff S, Jaworski E, Alvarado RE, Debbink K, Daugherty MD, Weaver SC, Routh AL, Walker DH, Plante KS, Menachery VD.
    J Virol; 2023 Feb 28; 97(2):e0153222. PubMed ID: 36722972
    [Abstract] [Full Text] [Related]

  • 11. Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales.
    Zeng C, Wu A, Wang Y, Xu S, Tang Y, Jin X, Wang S, Qin L, Sun Y, Fan C, Snijder EJ, Neuman BW, Chen Y, Ahola T, Guo D.
    J Virol; 2016 Aug 01; 90(15):6675-6685. PubMed ID: 27170751
    [Abstract] [Full Text] [Related]

  • 12. Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses.
    Lu Y, Cai H, Lu M, Ma Y, Li A, Gao Y, Zhou J, Gu H, Li J, Gu J.
    J Virol; 2020 Jul 30; 94(16):. PubMed ID: 32461321
    [Abstract] [Full Text] [Related]

  • 13. Natural evidence of coronaviral 2'-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding.
    Deng J, Yang S, Li Y, Tan X, Liu J, Yu Y, Ding Q, Fan C, Wang H, Chen X, Liu Q, Guo X, Gong F, Zhou L, Chen Y.
    Signal Transduct Target Ther; 2024 May 29; 9(1):140. PubMed ID: 38811528
    [Abstract] [Full Text] [Related]

  • 14.
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  • 15. N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition.
    Pan R, Kindler E, Cao L, Zhou Y, Zhang Z, Liu Q, Ebert N, Züst R, Sun Y, Gorbalenya AE, Perlman S, Thiel V, Chen Y, Guo D.
    mBio; 2022 Feb 22; 13(1):e0366221. PubMed ID: 35073761
    [Abstract] [Full Text] [Related]

  • 16. Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.
    Chen Y, Cai H, Pan J, Xiang N, Tien P, Ahola T, Guo D.
    Proc Natl Acad Sci U S A; 2009 Mar 03; 106(9):3484-9. PubMed ID: 19208801
    [Abstract] [Full Text] [Related]

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  • 18. Reconstitution of RNA cap methylation reveals different features of SARS-CoV-2 and SARS-CoV methyltransferases.
    He M, Cao L, Liu L, Jin X, Zheng B, Liu X, Zhuang J, Zhang F, Yang Z, Ji Y, Xu T, Huang S, Chen J, Xie L, Li K, Hou P, Pan J, Guo D, Li C.
    J Med Virol; 2024 Feb 03; 96(2):e29411. PubMed ID: 38285434
    [Abstract] [Full Text] [Related]

  • 19. Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase.
    Benoni R, Krafcikova P, Baranowski MR, Kowalska J, Boura E, Cahová H.
    Viruses; 2021 Aug 30; 13(9):. PubMed ID: 34578302
    [Abstract] [Full Text] [Related]

  • 20. Optimizing peptide inhibitors of SARS-Cov-2 nsp10/nsp16 methyltransferase predicted through molecular simulation and machine learning.
    Hamre JR, Jafri MS.
    Inform Med Unlocked; 2022 Aug 30; 29():100886. PubMed ID: 35252541
    [Abstract] [Full Text] [Related]

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