These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Targeting pancreatic cancer with a G-quadruplex ligand. Gunaratnam M, de la Fuente M, Hampel SM, Todd AK, Reszka AP, Schätzlein A, Neidle S. Bioorg Med Chem; 2011 Dec 01; 19(23):7151-7. PubMed ID: 22041170 [Abstract] [Full Text] [Related]
4. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands. Collie GW, Promontorio R, Hampel SM, Micco M, Neidle S, Parkinson GN. J Am Chem Soc; 2012 Feb 08; 134(5):2723-31. PubMed ID: 22280460 [Abstract] [Full Text] [Related]
5. A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line. Gunaratnam M, Collie GW, Reszka AP, Todd AK, Parkinson GN, Neidle S. Bioorg Med Chem; 2018 Jul 15; 26(11):2958-2964. PubMed ID: 29724653 [Abstract] [Full Text] [Related]
6. A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells. Ahmed AA, Marchetti C, Ohnmacht SA, Neidle S. Sci Rep; 2020 Jul 22; 10(1):12192. PubMed ID: 32699225 [Abstract] [Full Text] [Related]
10. Design and synthesis of dual functional NBD-fluorophore-incorporated naphthalene diimide derivatives as G-quadruplex ligands. Zhang X, Li Y, Chen Y, Liu Z, Li Z, Wang Z, Wang Y, Liu M. Bioorg Med Chem Lett; 2024 Oct 01; 111():129903. PubMed ID: 39053704 [Abstract] [Full Text] [Related]
13. Chelerythrine down regulates expression of VEGFA, BCL2 and KRAS by arresting G-Quadruplex structures at their promoter regions. Jana J, Mondal S, Bhattacharjee P, Sengupta P, Roychowdhury T, Saha P, Kundu P, Chatterjee S. Sci Rep; 2017 Jan 19; 7():40706. PubMed ID: 28102286 [Abstract] [Full Text] [Related]
14. The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer. Ahmed AA, Greenhalf W, Palmer DH, Williams N, Worthington J, Arshad T, Haider S, Alexandrou E, Guneri D, Waller ZAE, Neidle S. Molecules; 2023 Mar 07; 28(6):. PubMed ID: 36985425 [Abstract] [Full Text] [Related]