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288 related items for PubMed ID: 26085680

  • 1. TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway.
    Bergstrøm B, Aune MH, Awuh JA, Kojen JF, Blix KJ, Ryan L, Flo TH, Mollnes TE, Espevik T, Stenvik J.
    J Immunol; 2015 Aug 01; 195(3):1100-11. PubMed ID: 26085680
    [Abstract] [Full Text] [Related]

  • 2. Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling.
    Moen SH, Ehrnström B, Kojen JF, Yurchenko M, Beckwith KS, Afset JE, Damås JK, Hu Z, Yin H, Espevik T, Stenvik J.
    Front Immunol; 2019 Aug 01; 10():1209. PubMed ID: 31214180
    [Abstract] [Full Text] [Related]

  • 3. Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages.
    Ehrnström B, Beckwith KS, Yurchenko M, Moen SH, Kojen JF, Lentini G, Teti G, Damås JK, Espevik T, Stenvik J.
    Front Immunol; 2017 Aug 01; 8():1243. PubMed ID: 29042860
    [Abstract] [Full Text] [Related]

  • 4. IRAK4 kinase activity controls Toll-like receptor-induced inflammation through the transcription factor IRF5 in primary human monocytes.
    Cushing L, Winkler A, Jelinsky SA, Lee K, Korver W, Hawtin R, Rao VR, Fleming M, Lin LL.
    J Biol Chem; 2017 Nov 10; 292(45):18689-18698. PubMed ID: 28924041
    [Abstract] [Full Text] [Related]

  • 5. Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes.
    Cervantes JL, La Vake CJ, Weinerman B, Luu S, O'Connell C, Verardi PH, Salazar JC.
    J Leukoc Biol; 2013 Dec 10; 94(6):1231-41. PubMed ID: 23906644
    [Abstract] [Full Text] [Related]

  • 6. TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes.
    Eigenbrod T, Pelka K, Latz E, Kreikemeyer B, Dalpke AH.
    J Immunol; 2015 Aug 01; 195(3):1092-9. PubMed ID: 26101323
    [Abstract] [Full Text] [Related]

  • 7. Toll-like receptor 2-dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival.
    Musilova J, Mulcahy ME, Kuijk MM, McLoughlin RM, Bowie AG.
    J Biol Chem; 2019 Nov 08; 294(45):17031-17042. PubMed ID: 31558608
    [Abstract] [Full Text] [Related]

  • 8. CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.
    Yang C, Bachu M, Du Y, Brauner C, Yuan R, Ah Kioon MD, Chesi G, Barrat FJ, Ivashkiv LB.
    Nat Commun; 2022 Jun 14; 13(1):3426. PubMed ID: 35701499
    [Abstract] [Full Text] [Related]

  • 9. FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.
    Hoepel W, Newling M, Vogelpoel LTC, Sritharan L, Hansen IS, Kapsenberg ML, Baeten DLP, Everts B, den Dunnen J.
    Front Immunol; 2019 Jun 14; 10():739. PubMed ID: 31024565
    [Abstract] [Full Text] [Related]

  • 10. Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta.
    Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ, Radolf JD, Salazar JC.
    Proc Natl Acad Sci U S A; 2011 Mar 01; 108(9):3683-8. PubMed ID: 21321205
    [Abstract] [Full Text] [Related]

  • 11. Interferon regulatory factor 5 and nuclear factor kappa-B exhibit cooperating but also divergent roles in the regulation of pro-inflammatory cytokines important for the development of TH1 and TH17 responses.
    Stein T, Wollschlegel A, Te H, Weiss J, Joshi K, Kinzel B, Billich A, Guntermann C, Lehmann JCU.
    FEBS J; 2018 Aug 01; 285(16):3097-3113. PubMed ID: 29971953
    [Abstract] [Full Text] [Related]

  • 12. Possible role of Toll-like receptor-2 in the intracellular survival of Staphylococcus aureus in murine peritoneal macrophages: involvement of cytokines and anti-oxidant enzymes.
    Bishayi B, Bandyopadhyay D, Majhi A, Adhikary R.
    Scand J Immunol; 2014 Aug 01; 80(2):127-43. PubMed ID: 24846691
    [Abstract] [Full Text] [Related]

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  • 14. An alternative model for type I interferon induction downstream of human TLR2.
    Oosenbrug T, van de Graaff MJ, Haks MC, van Kasteren S, Ressing ME.
    J Biol Chem; 2020 Oct 16; 295(42):14325-14342. PubMed ID: 32796029
    [Abstract] [Full Text] [Related]

  • 15. Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages.
    Schilling D, Thomas K, Nixdorff K, Vogel SN, Fenton MJ.
    J Immunol; 2002 Nov 15; 169(10):5874-80. PubMed ID: 12421970
    [Abstract] [Full Text] [Related]

  • 16. Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.
    Krüger A, Oldenburg M, Chebrolu C, Beisser D, Kolter J, Sigmund AM, Steinmann J, Schäfer S, Hochrein H, Rahmann S, Wagner H, Henneke P, Hornung V, Buer J, Kirschning CJ.
    EMBO Rep; 2015 Dec 15; 16(12):1656-63. PubMed ID: 26545385
    [Abstract] [Full Text] [Related]

  • 17. TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages.
    Odoardi N, Kourko O, Petes C, Basta S, Gee K.
    J Innate Immun; 2021 Dec 15; 13(6):345-358. PubMed ID: 34058746
    [Abstract] [Full Text] [Related]

  • 18. TRAM is required for TLR2 endosomal signaling to type I IFN induction.
    Stack J, Doyle SL, Connolly DJ, Reinert LS, O'Keeffe KM, McLoughlin RM, Paludan SR, Bowie AG.
    J Immunol; 2014 Dec 15; 193(12):6090-102. PubMed ID: 25385819
    [Abstract] [Full Text] [Related]

  • 19. The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
    Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT.
    J Biol Chem; 2005 Apr 29; 280(17):17005-12. PubMed ID: 15695821
    [Abstract] [Full Text] [Related]

  • 20. Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta.
    Salazar JC, Duhnam-Ems S, La Vake C, Cruz AR, Moore MW, Caimano MJ, Velez-Climent L, Shupe J, Krueger W, Radolf JD.
    PLoS Pathog; 2009 May 29; 5(5):e1000444. PubMed ID: 19461888
    [Abstract] [Full Text] [Related]

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