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352 related items for PubMed ID: 26124132

  • 1. Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice.
    Yuan CC, Muthu P, Kazmierczak K, Liang J, Huang W, Irving TC, Kanashiro-Takeuchi RM, Hare JM, Szczesna-Cordary D.
    Proc Natl Acad Sci U S A; 2015 Jul 28; 112(30):E4138-46. PubMed ID: 26124132
    [Abstract] [Full Text] [Related]

  • 2. Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM.
    Yadav S, Yuan CC, Kazmierczak K, Liang J, Huang W, Takeuchi LM, Kanashiro-Takeuchi RM, Szczesna-Cordary D.
    J Mol Med (Berl); 2019 Jul 28; 97(7):1033-1047. PubMed ID: 31101927
    [Abstract] [Full Text] [Related]

  • 3. In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain.
    Muthu P, Liang J, Schmidt W, Moore JR, Szczesna-Cordary D.
    Arch Biochem Biophys; 2014 Jun 15; 552-553():29-39. PubMed ID: 24374283
    [Abstract] [Full Text] [Related]

  • 4. Phosphomimetic-mediated in vitro rescue of hypertrophic cardiomyopathy linked to R58Q mutation in myosin regulatory light chain.
    Yadav S, Kazmierczak K, Liang J, Sitbon YH, Szczesna-Cordary D.
    FEBS J; 2019 Jan 15; 286(1):151-168. PubMed ID: 30430732
    [Abstract] [Full Text] [Related]

  • 5. Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation.
    Liang J, Kazmierczak K, Veerasammy M, Yadav S, Takeuchi L, Kanashiro-Takeuchi R, Szczesna-Cordary D.
    Cytoskeleton (Hoboken); 2024 Dec 15; 81(12):806-814. PubMed ID: 38494592
    [Abstract] [Full Text] [Related]

  • 6. The effect of myosin RLC phosphorylation in normal and cardiomyopathic mouse hearts.
    Muthu P, Kazmierczak K, Jones M, Szczesna-Cordary D.
    J Cell Mol Med; 2012 Apr 15; 16(4):911-9. PubMed ID: 21696541
    [Abstract] [Full Text] [Related]

  • 7. Malignant familial hypertrophic cardiomyopathy D166V mutation in the ventricular myosin regulatory light chain causes profound effects in skinned and intact papillary muscle fibers from transgenic mice.
    Kerrick WG, Kazmierczak K, Xu Y, Wang Y, Szczesna-Cordary D.
    FASEB J; 2009 Mar 15; 23(3):855-65. PubMed ID: 18987303
    [Abstract] [Full Text] [Related]

  • 8. Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin.
    Yuan CC, Kazmierczak K, Liang J, Ma W, Irving TC, Szczesna-Cordary D.
    Proc Natl Acad Sci U S A; 2022 Feb 22; 119(8):. PubMed ID: 35177471
    [Abstract] [Full Text] [Related]

  • 9. Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.
    Huang W, Liang J, Kazmierczak K, Muthu P, Duggal D, Farman GP, Sorensen L, Pozios I, Abraham TP, Moore JR, Borejdo J, Szczesna-Cordary D.
    J Mol Cell Cardiol; 2014 Sep 22; 74():318-29. PubMed ID: 24992035
    [Abstract] [Full Text] [Related]

  • 10. Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart.
    Muthu P, Mettikolla P, Calander N, Luchowski R, Gryczynski I, Gryczynski Z, Szczesna-Cordary D, Borejdo J.
    J Mol Cell Cardiol; 2010 May 22; 48(5):989-98. PubMed ID: 19914255
    [Abstract] [Full Text] [Related]

  • 11. Hypertrophic cardiomyopathy associated E22K mutation in myosin regulatory light chain decreases calcium-activated tension and stiffness and reduces myofilament Ca2+ sensitivity.
    Zhang J, Wang L, Kazmierczak K, Yun H, Szczesna-Cordary D, Kawai M.
    FEBS J; 2021 Aug 22; 288(15):4596-4613. PubMed ID: 33548158
    [Abstract] [Full Text] [Related]

  • 12. The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice.
    Szczesna-Cordary D, Guzman G, Zhao J, Hernandez O, Wei J, Diaz-Perez Z.
    J Cell Sci; 2005 Aug 15; 118(Pt 16):3675-83. PubMed ID: 16076902
    [Abstract] [Full Text] [Related]

  • 13. Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice.
    Abraham TP, Jones M, Kazmierczak K, Liang HY, Pinheiro AC, Wagg CS, Lopaschuk GD, Szczesna-Cordary D.
    Cardiovasc Res; 2009 Apr 01; 82(1):84-92. PubMed ID: 19150977
    [Abstract] [Full Text] [Related]

  • 14. Functional comparison of phosphomimetic S15D and T160D mutants of myosin regulatory light chain exchanged in cardiac muscle preparations of HCM and WT mice.
    Kazmierczak K, Liang J, Gomez-Guevara M, Szczesna-Cordary D.
    Front Cardiovasc Med; 2022 Apr 01; 9():988066. PubMed ID: 36204565
    [Abstract] [Full Text] [Related]

  • 15. Discrete effects of A57G-myosin essential light chain mutation associated with familial hypertrophic cardiomyopathy.
    Kazmierczak K, Paulino EC, Huang W, Muthu P, Liang J, Yuan CC, Rojas AI, Hare JM, Szczesna-Cordary D.
    Am J Physiol Heart Circ Physiol; 2013 Aug 15; 305(4):H575-89. PubMed ID: 23748425
    [Abstract] [Full Text] [Related]

  • 16. Phosphorylation Mimetic of Myosin Regulatory Light Chain Mitigates Cardiomyopathy-Induced Myofilament Impairment in Mouse Models of RCM and DCM.
    Kazmierczak K, Liang J, Maura LG, Scott NK, Szczesna-Cordary D.
    Life (Basel); 2023 Jun 28; 13(7):. PubMed ID: 37511838
    [Abstract] [Full Text] [Related]

  • 17. Mavacamten decreases maximal force and Ca2+ sensitivity in the N47K-myosin regulatory light chain mouse model of hypertrophic cardiomyopathy.
    Awinda PO, Watanabe M, Bishaw Y, Huckabee AM, Agonias KB, Kazmierczak K, Szczesna-Cordary D, Tanner BCW.
    Am J Physiol Heart Circ Physiol; 2021 Feb 01; 320(2):H881-H890. PubMed ID: 33337957
    [Abstract] [Full Text] [Related]

  • 18. Myosin regulatory light chain phosphorylation enhances cardiac β-myosin in vitro motility under load.
    Karabina A, Kazmierczak K, Szczesna-Cordary D, Moore JR.
    Arch Biochem Biophys; 2015 Aug 15; 580():14-21. PubMed ID: 26116789
    [Abstract] [Full Text] [Related]

  • 19. Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain.
    Huang W, Kazmierczak K, Zhou Z, Aguiar-Pulido V, Narasimhan G, Szczesna-Cordary D.
    Arch Biochem Biophys; 2016 Jul 01; 601():121-32. PubMed ID: 26906074
    [Abstract] [Full Text] [Related]

  • 20. Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients.
    Szczesna-Cordary D, Jones M, Moore JR, Watt J, Kerrick WG, Xu Y, Wang Y, Wagg C, Lopaschuk GD.
    FASEB J; 2007 Dec 01; 21(14):3974-85. PubMed ID: 17606808
    [Abstract] [Full Text] [Related]

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